Kromanngertsen8206

A standard expectation of primordial cosmological inflation is that it dilutes all relics created before its onset to unobservable levels. We present a counterexample to this expectation by demonstrating that a network of cosmic strings diluted by inflation can regrow to a level that is potentially observable today in gravitational waves (GWs). In contrast to undiluted cosmic strings, whose primary GW signals are typically in the form of a stochastic GW background, the leading signal from a diluted cosmic string network can be distinctive bursts of GWs within the sensitivity reach of current and future GW observatories.We present a theoretical study of vortices in arrays of photon condensates. Even when interactions are negligible, as is the case in current experiments, pumping and losses can lead to a finite vortex core size. While some properties of photon condensate vortices, such as their self-acceleration and the generation of vortex pairs by a moving vortex resemble those in lasers and interacting polariton condensates far from equilibrium, in several aspects they differ from previously studied systems the vortex core size is determined by the balance between pumping and tunneling, the core appears oblate in the direction of its motion, and new vortex pairs can spontaneously nucleate in the core region.Multiloop matter-wave interferometers are essential in quantum sensing to measure the derivatives of physical quantities in time or space. Because multiloop interferometers require multiple reflections, imperfections of the matter-wave mirrors create spurious paths that scramble the signal of interest. Here, we demonstrate a method of adjustable momentum transfer that prevents the recombination of the spurious paths in a double-loop atom interferometer aimed at measuring rotation rates. We experimentally study the recombination condition of the spurious matter waves, which is quantitatively supported by a model accounting for the coherence properties of the atomic source. We finally demonstrate the effectiveness of the method in building a cold-atom gyroscope with a single-shot acceleration sensitivity suppressed by a factor of at least 50. Our study will impact the design of multiloop atom interferometers that measure a single inertial quantity.We propose a hybrid quantum-classical atomic clock where the interrogation of atoms prepared in a spin-coherent (or weakly squeezed) state is used to feed back one or more highly spin-squeezed atomic states toward their optimal phase-sensitivity point. The hybrid clock overcomes the stability of a single Ramsey clock using coherent or optimal spin-squeezed states and reaches a Heisenberg-limited stability while avoiding nondestructive measurements. When optimized with respect to the total number of particles, the protocol surpasses the state-of-the-art proposals that use Greenberger-Horne-Zeilinger or NOON states. We compare analytical predictions with numerical simulations of clock operations, including correlated 1/f local oscillator noise.Despite extensive shock wave and static compression experiments and corresponding theoretical work, consensus on the crystal structure and the melt boundary of Fe at Earth's core conditions is lacking. We present in situ x-ray diffraction measurements in laser-shock compressed Fe that establish the stability of the hexagonal-close-packed (hcp) structure along the Hugoniot through shock melting, which occurs between ∼242 to ∼247  GPa. Using previously reported hcp Fe Hugoniot temperatures, the melt temperature is estimated to be 5560(360) K at 242 GPa, consistent with several reported Fe melt curves. Extrapolation of this value suggests ∼6400  K melt temperature at Earth's inner core boundary pressure.

Patients with diabetes mellitus (DM) are susceptible to invasive fungal rhinosinusitis (IFRS). The mortality rate of IFRS varies greatly among the patients with DM.

To identify the prognostic factors for the overall survival of patients with DM and IFRS.

A retrospective study was conducted in four tertiary hospitals in Thailand, Malaysia and Myanmar. Patients diagnosed with IFRS and DM from 2008 to 2019 were identified. The outcome was the overall survival. Variables analyzed for risk factors were age, HbA1C level, ketoacidosis, white blood cell count, hyperglycemia, duration of DM, current use of diabetic medications, serum creatinine level, and the extensions of IFRS to the orbit, the cavernous sinus and intracranial cavity.

Sixty-five diabetic patients with IFRS (age 57.9 ± 13.4 years, male 60%) were identified. SS-31 clinical trial The mortality rate was 21.5%. The extensions of IFRS to the cavernous sinus (hazard ratio 5.1, 95% CI [1.4-18.2], p = 0.01) and intracranial cavity (hazard ratio 3.4, 95% CI [1.1-11.3, p = 0.05) predicted mortality. Current use of diabetic medications decreased the mortality risk (hazard ratio 0.2, 95% CI [0.1-0.9], p = 0.03). The 6-month overall survival of the patients with and without the cavernous sinus extension were 51.4% and 83.6%, (p = 0.001), with and without intracranial extension 53.3% and 88.9%, (p = 0.001), and with and without current diabetic medications 82.3% and 57.5%, respectively (p = 0.045).

The extensions of IFRS to the cavernous sinus and intracranial cavity increased the risk of death in patients with DM. Survival was primarily related to current use of diabetic medications.

The extensions of IFRS to the cavernous sinus and intracranial cavity increased the risk of death in patients with DM. Survival was primarily related to current use of diabetic medications.This systematic review aims to identify prognostic factors for the overall survival of invasive fungal rhinosinusitis (IFRS) in patients with diabetes using original data from the existing published articles. Systematic searches of Medline, EMBASE, and Cochrane Library databases were performed to include articles from 1988 to 2019 using the terms "fung*" AND "rhinosinusitis" AND "invasive" AND "diabetes OR ketoacidosis". Data from 258 diabetic patients with IFRS (mean age 55.9 years, 55.6% male, 124 studies) were extracted for data analysis. The mortality rate was 31.8%. Seven variables plasma glucose level, HbA1C, ketoacidosis, leukopenia, serum creatinine level, duration of diabetes, and the cavernous sinus extension were assessed. Univariate analysis was done for each variable and revealed that the cavernous sinus extension was a significant risk factor. Multivariable logistic regression analysis confirmed that the cavernous sinus extension independently predicted mortality in patients with diabetes (hazard ratio (HR) 2.