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This case highlights the importance of an early diagnosis and a multidisciplinary approach in managing LS to minimize the mortality and long-term morbidity of this relatively rare and complicated multisystem disease.Rhabdomyolysis is caused by necrosis of muscles and leakage of intracellular contents into blood circulation. It is most commonly caused by trauma, crush injuries, drugs, toxins, immobilization, compartment syndrome, prolonged surgical procedures, and less likely by infections. Infection-related rhabdomyolysis is rare, but not uncommon, and is seen in both viral and bacterial infections. Extrapulmonary manifestations of coronavirus disease 2019 (COVID-19) include thrombotic like pulmonary emboli, acute cerebrovascular accident, myocardial infarction, cardiac arrhythmias, liver injury, gangrene, diarrhea, acute renal failure, and so on. We here describe a case of COVID-19-induced rhabdomyolysis in a 19-year-old Hispanic male presenting with muscle aches, fatigue, fevers, and no pulmonary symptoms.Abdominal epilepsy (AE) is a very rare diagnosis; it is considered to be a category of temporal lobe epilepsies and is more commonly a diagnosis of exclusion. Demographic presentation of AE is usually in the pediatric age group. However, there is recorded documentation of its occurrence even in adults. AE can present with unexplained, relentless, and recurrent gastrointestinal symptoms such as paroxysmal pain, nausea, bloating, and diarrhoea that improve with antiepileptic therapy. It is commonly linked with electroencephalography (EEG) changes in the temporal lobes along with symptoms that reflect the involvement of the central nervous system (CNS) such as altered consciousness, confusion, and lethargy. Due to the vague nature of these symptoms, there is a high chance of misdiagnosing a patient. We present the case of a 20-year-old man with AE who was misdiagnosed with psychogenic abdominal pain after undergoing multiple investigations with various hospital departments.The radio-immunization effects of radiotherapy with abscopal tumor regressions have been documented in several experimental and clinical studies. Here, we present a patient with bladder cancer and relapsed metastatic disease to the left supraclavicular/axillary area and left lung. Concurrent weekly hypofractionated radiotherapy of both areas (8Gy/fraction/week, four fractions in total) and bi-weekly immunotherapy with anti-programmed cell death protein 1 (anti-PD-1) monoclonal antibodies resulted in complete regression of the axillary metastatic masses and of the lung metastasis, three months after the onset of therapy. In CT scans, however, a sternum infiltrating mass growing proximal to the margins of the radiotherapy fields was strikingly evident, while multiple hepatic metastases also appeared. Lymphopenia during radio-immunotherapy was recorded. The current report does not confirm the abscopal effects of radio-immunotherapy and furthermore, suggests that progressive disease or even hyper-progression may occur in a subgroup of patients. Although radio-vaccination is a well-established phenomenon, it is evident that we still miss major aspects of host/tumor-immune interactions with radiation.Background Prevalence and mortality rates during the coronavirus disease 2019 (COVID-19) pandemic have varied widely across nations. This phenomenon may be partly due to regional variations in health-related behaviours, some of which may be influenced by health anxiety. A functional polymorphism of the catechol O-methyltransferase (COMT) gene, designated rs4680 or Val158Met, has been associated with anxiety-related behaviours and the so-called "worrier" phenotype. Methods In this exploratory study, an analysis of the correlation between the frequencies of the Met allele of the COMT gene across 28 countries, obtained from the public domain Allele Frequency Database (ALFRED), and the COVID-19 prevalence and mortality rates in these countries, obtained from the Johns Hopkins Medical University web-based dashboard, was carried out while controlling for population size and median age in each country. Results Allele frequencies varied widely across populations. Met allele frequency was positively correlated with COVID-19 prevalence (ρ = 0.527, p = 0.004) and mortality rate (ρ = 0.542, p = 0.003) across nations. However, this correlation was no longer significant after controlling for confounders. Conclusions These preliminary results suggest that there may be a relationship between the COMT Val158Met or rs4680 functional polymorphism and the impact of COVID-19 across nations, which could plausibly be mediated by maladaptive anxiety-related behaviours.Electrosurgery is one of the advances in the surgical field and used commonly. Modern electrosurgical units considered relatively safe. Although rare, inadvertent skin burns due to electrosurgery caused by different mechanisms were reported in the literature. https://www.selleckchem.com/products/OSI-906.html Positioning the patient in prone is required for some surgeries and utilizing this position in a proper manner is essential to avoid complications. We present a case of a 47-year-old female patient who underwent uneventful spinal surgery in a prone position. The patient complained of pain in fingers postoperatively that revealed third-degree skin burn. Plastic surgery was involved in the treatment of burns and the patient followed regularly until fully healed. This case study aims to prompt awareness among surgeons and the staff of the operation-room regarding the unintended burn of patients caused by aberrant circuit related to electrosurgery in prone position.Introduction The internet is an important source of health information, and yet the quality of the resources that patients' access can vary widely. Previous research has evaluated the quality of information for several types of cancer; however, this has not yet been done for cervical cancer beyond treatment information. The goal of this project was to systematically evaluate the quality of resources for cervical cancer information available against a range of metrics, including content breadth and accuracy, readability, and accountability. Methods An internet search was performed using the term "cervical cancer" using Google and two meta-search engines, Dogpile and Yippy. The top-100 websites returned across all three engines were evaluated using a validated structured rating tool. Results Only 32% of websites disclosed their author and only 38% used citations, while 64% of websites had been updated in the last two years. Readability was at university-level or higher for 19% of websites, and high-school level for 78%.