Baunjansen7970

Most of the newborns presented mild severity at admission, but 24% of them had SBI, thus hospitalization and close clinical observation are always necessary. Laboratory tests, such as CRP, white blood cell and neutrophils count are not good predictors of SBI. Early treatment with antibio tics for patients who meet the low-risk criteria is debatable.

To describe the socio-epidemiological characteristics of Pediatric Tuberculosis (TB) ca ses, and aspects associated with its incidence, from 2005 to 2018, in North, Central, and South Metro politan Health Services of Chile.

Descriptive study with an ecological time se ries. We studied the incidence of annual global TB and according to age, sex, location of tuberculosis, bacteriological confirmation, human immunodeficiency virus (HIV) co-infection, country of origin, and effectiveness of anti-tuberculosis therapy. In addition, a correlation analysis was made between the incidence rate and the proportion of foreign cases.

Between 2005 and 2018, 160 cases of TB were reported in children under 15, with a median age of 8 years, and 55% male. 56.2% corres ponded to Pulmonary TB, of which 65.6% were bacteriologically confirmed. The incidence rate in creased from 0.5 cases x 100,000 inhabitants in 2010, to 4.9 cases x 100,000 inhabitants in 2018. This last year concentrated 20.6% of the cases that occurred in 14 years of observation. The proportion of cases in foreign minors is still lower compared with the cases in Chilean children. A 91.3% success rate, 6.5% of cases transferred to other Services, and 2 deaths were also observed.

The results of this study show a serious epidemiological reemergence of TB. We recommend that control and eradication policies consider strategies focused on pediatric patients, aiming at actively screening for new cases and more efficient contact tracing.

The results of this study show a serious epidemiological reemergence of TB. We recommend that control and eradication policies consider strategies focused on pediatric patients, aiming at actively screening for new cases and more efficient contact tracing.

The educational level of the adult population is related to obesity, but there is little knowledge regar ding the relationship of parents' educational level with the obesity and muscle strength of Chilean pre-school children.

To describe the levels of adiposity and muscular strength of pre schoolers, according to the educational level and socio-demographic characteristics of their parents.

Descriptive, cross-sectional study with participation of pre-schoolers from kindergartens and their parents (n = 99). Variables studied were a) socio-demographic (survey with 4 items), b) anthropometry (weight, height, weight/height ratio, weight/height-z, and body mass index), c) body composition (fat mass in kg and %, muscle mass), and d) muscle strength (hand grip muscle strength). The association between the above factors and the educational level of the parents [mother or father] of "low" [Low-EL] or "high" educational level [High-EL] were analy sed.

There were significant differences between the weight/height according to the parents' educational level (father Low-EL; 0.088 ± 0.170 vs High-EL -0.060 ± 0.163, P = 0.024), and in the percentage of fat mass (father Low-EL; 30.8 ± 0.8 vs High-EL; 28.7 ± 0.9%, P = 0.040). In the rest of the obesity markers, there were no significant differences according to the parents' educational level nor in strength and muscle mass.

Pre-school children of parents with low educational level show significantly higher values of weight/height and percentage of fat mass than those peers with parents with high educational level. These findings require further and more complex research to be corroborated.

Pre-school children of parents with low educational level show significantly higher values of weight/height and percentage of fat mass than those peers with parents with high educational level. These findings require further and more complex research to be corroborated.

The treatment of acute lymphoblastic leukemia (ALL) includes the use of asparaginase (ASP), a drug associated with hypersensitivity reactions (HSR) that requires discontinuing its use.

To determine the incidence of HSR associated with ASP that require discontinuation of its use and des cribe them, and to verify if there is a relationship between HSR incidence and protocols or survival.

Retrospective study. Clinical records of all patients (1-15 years) diagnosed with ALL between January 2010 and December 2015 at the Hospital Luis Calvo Mackenna were reviewed. see more The incidence of HSR to ASP was determined and classified according to the CTCAE v5.0 severity score. We analyzed the relative risk of HSR using Fisher's test and the survival with the Kaplan-Meier estimator.

110 patients were collected. During the first treatment (ALL-IC- BFM), the incidence of HSR to L-ASP was 55%, therefore it was changed to PEG-ASP as second-line treatment, and 44% of them had HSR, and ASP should discontinued in 25% of patients. Of all the HSR to ASP, 77% were anaphylactic (CTCAE 3-5). Patients treated with augmented IB protocol were at higher risk of not completing ASP treatment due to HSR, RR 3.81 (95% CI, 1.98-7.31, p = 0.0001). Patients without HSR in ALL-IC-BFM were at lower risk of relapse, HR 0.29 (95% CI, 0.14-0.62, p = 0.0013). Considering all treatments (ALL-IC-BFM and relapse), patients who completed the ASP treatment had higher overall survival, HR 0.20 (95% CI, 0.07-0.57, p = 0.0026).

HSR to ASP that require discontinuation of treatment are frequent in children with ALL, most of them were severe anaphylactic reactions. This study suggests a better prognosis in patients without HSR to ASP.

HSR to ASP that require discontinuation of treatment are frequent in children with ALL, most of them were severe anaphylactic reactions. This study suggests a better prognosis in patients without HSR to ASP.The implications of closing educational establishments during the COVID-19 pandemic and the dis cussion about the opening of them, invite and require us to consider, from different positions and responsibilities, the changes that we must make as a society at the educational level. In this article, a group of health professionals collects information and reflects on the repercussions of returning or not to school activities, in terms of physical and emotional health and academic education. Based on what is known to be protective factors and possible threats to return, it is possible to conclude that each local reality must make its own informed decision, with the participation of all its members, seeking the common good, which favors students, protects teachers, and privileges the role of the educational system in socio-emotional learning. School is a space for containing the emotions and adaptation needs that students and their families have experienced in these uncertain times. We all have a level of responsibility in building a new civilization around these issues that link education, physical and mental health, social collaboration, and individual responsibility.