Rileywinters3812
Biological, genetic and psychosocial factors may play a role in the aetiology of bipolar mood disorder (BPD). BPD episodes might be triggered by isotretinoin, a retinoid derivative of vitamin A with a role in cellular proliferation and differentiation. Due to its association with depression, suicidal ideation and suicide attempts, American Food and Drug Administration (FDA) issued a placement of a label warning for isotretionin. Personal or family history of psychiatric disorders was emphasized in the literature for the risk of mood episodes following isotretionin treatment. Here we aim to present the case of an 18- year old young male adult, without personal or family history of a psychiatric disorder, who developed psychotic mania within the first week of isoretinoin which was prescribed for acne vulgaris. Psychotic mania symptoms receded within one week after starting olanzapine (10 mg/day). We believe this case is significant in demonstrating the occurence of a manic episode after isoretinoin in individuals lacking a personal or family history of psychiatric diagnoses.Avoidant/Restrictive food intake disorder (ARFID) is a diagnostic category that is included in the DSM 5 (American Psychiatric Association- APA 2013) and proposed by the ICD11 (The World Health Organisation-WHO 2019). Very few ARFID cases have been reported to date. This report aims to present the case of a 25-year-old female who was diagnosed with ARFID and thereby to discuss the challenges in diagnosing and managing the case.
This review article discusses the multi-dimensional and complex pattern of filicide from a psychodynamic perspective with reference to the recent publications. Creating awareness to filicide among professionals will help to the correct assessment of the cases, recognition of and intervention on filicide before the act, and the development of preventive mechanisms.
Published articles between January 1960 and March 2020 were searched using the keywords 'filicide, infanticide, neonaticide, mother/ parent/ maternal/ paternal, psychodynamics' in the Google Scholar, EBSCHO-HOST, Science-Direct, PubMed and Web of Science databases.
The term filicide refers to the murder of the offspring by the parent. Although it is a common belief that the children are murdered boy strangers, the reported figures may not be representing the truth. No families are detected in one fourth of all murdered infants within the first 24 hours. The death of abondoned children are classified as 'due to natural causes'. Some murders mige'. However it is crucial to elucidate the psychodinamic background on violence and discuss the risk factors, triggers, background dynamics and psychopathologies underlying this phenomenon.
The Observable Social Cognition-A Rating Scale (OSCARS) is an eight-item, interview-based psychometric tool that was developed by Healey et al. (2015) for evaluating social cognition with respect to the theory of mind, emotion perception, and attributional style in schizophrenia. The aim of this study is to determine the validity and reliability of the Turkish version of the scale.
The study was conducted with 50 patients with schizophrenia and schizoaffective disorder and 50 relatives of these patients using the OSCARS, the Face Emotion Discrimination/Identification Test (FEDT/FEIT), the Positive and Negative Symptoms Scale (PANSS), the Global Assessment of Functioning (GAF) and the Dokuz Eylül Theory of Mind Index (DEZIKO). The validity of the OSCARS was assessed by exploratory factor analysis and concurrent validity analysis, the reliability was demonstrated by the internal consistency coefficient, item-total item correlation, and test-retest comparisons.
The Cronbach's alpha coefficient of the OSCARS-TR was 0.83. Explanatory factor analysis yielded a 2-factor structure explaining 64.2% of the total variance of the scale. The total score of the OSCARSTR correlated significantly with the DEZIKO (r=-0.49), the GAF (r=- 0.50), the PANSS (r=0.54) and the FEDT (r=-0.29) total scores but not with the FEIT scores. The total scores of the OSCARS-TR completed by the patients and by the relatives of the patients correlated with statistical significance (r=0.93). The test-retest reliability coefficient of OSCARS-TR was 0.95.
The results demonstrated the validity and the reliability of the OSCARS-TR. The scale can be easily implemented on an interview basis as an appropriate tool for evaluating social cognition.
The results demonstrated the validity and the reliability of the OSCARS-TR. The scale can be easily implemented on an interview basis as an appropriate tool for evaluating social cognition.
The aim of this study is to adapt Perceived Devaluation- Discrimination (PDD) scale for Turkish language and culture.
Participants from clinical and community populations were included in the study. https://www.selleckchem.com/products/d-ap5.html The community sample consisted of 145 healthy individuals from the general community and the clinical sample consisted of 85 individuals with chronic psychiatric disorders. Psychometric properties of the Turkish version of PDD were assessed in the general community and clinical samples. Exploratory factor analysis, confirmatory factor analysis, internal consistency analysis, convergent and discriminant validity analyses were conducted.
As a result of exploratory factor analysis, a two-factor structure for PDD emerged in both the general community and clinical samples. Confirmatory factor analysis also supported the two-factor structure in both samples. These factors were named as Perceived Discrimination and Negative Evaluation and Perceived Acceptance and Non-negative Evaluation subscales. Cronbach's alpha values for PDD were 0.76 in the general community sample and 0.79 in the clinical sample. Alpha values of PDD subscales ranged between 0.72 and 0.77 in both samples. While convergent and discriminant validity tests provided partial support for construct validity of PDD in the general community sample, the convergent validity tests conducted with the clinical sample provided evidence for validity of PDD.
Based on the results of the present study, it has been demonstrated that the Turkish version of PDD is reliable and valid and can be used with community and clinical samples to measure perceived devaluation and discrimination.
Based on the results of the present study, it has been demonstrated that the Turkish version of PDD is reliable and valid and can be used with community and clinical samples to measure perceived devaluation and discrimination.
In this study, the retinal nerve fiber layer (RNFL) thicknesses were compared between adult attention deficit hyperactivity disorder (ADHD) cases and healthy controls.
The study included adults diagnosed with ADHD based on the DSM-5 criteria and age and gender matched healthy controls. Spectral area optical coherence tomography (OCT) was performed on the 52 eyes of 26 participants with ADHD and the 52 eyes of the 26 healthy control individuals.
Comparing the data on the 52 eyes of 26 ADHD participants and the 52 eyes of 26 healthy control participants indicated that the central macular thickness (CMT) and the RNFL thicknesses, the ganglion cell complex (GCC), the mean inner macular ring (MIRAVG) and the mean outer macular ring (MOR-AVG) thicknesses were significantly lower in the ADHD group.
This is the first study in the literature on the RNFL thickness in adult ADHD patients. Our findings demonstrated that RNFL thickness is lower in ADHD cases as the unmyelinated axons are reduced in ADHD. Hence, the quantitative and reproducible nature of Spectral Domain-OCT thickness measurements can be used as biomarkers to monitor disease progression in ADHD cases.
This is the first study in the literature on the RNFL thickness in adult ADHD patients. Our findings demonstrated that RNFL thickness is lower in ADHD cases as the unmyelinated axons are reduced in ADHD. Hence, the quantitative and reproducible nature of Spectral Domain-OCT thickness measurements can be used as biomarkers to monitor disease progression in ADHD cases.
In this study, we aimed to investigate whether there is a fast decay in the iconic memory of patients with Obsessive Compulsive Disorder (OCD) compared to healthy individuals by taking into consideration the clinical OCD subtypes.
The study included 74 patients diagnosed with OCD on the basis of the DSM 5 criteria and 63 healthy individuals. The OCD patients were grouped as washers, checkers, both washers and checkers, and non-washers and non-checkers. All participants took a partial report test (PRT) to compare iconic memory performance between the healthy control group and the OCD group as a whole and in OCD subgroups.
Loss of iconic memory did not differ between OCD group and the controls. The iconic memory scores, expressed as the d' values, at specified time points correlated negatively with age and positively with education duration in all groups. When the subgroup data were analyzed by controlling for age, the d1'value showing formation of iconic information was lower in the washers subgroup in comparison to the checkers subgroup and the nonwashers and non-checkers subgroup. The d7' value was also lower in the washers subgroup than in the the non-washers and non-checkers subgroup and the healthy control group. The iconic decay rate of the washers subgroup between the time points d6' and d7' was significantly higher in comparison to the healthy control group. The scores of OCD patients on the washing subscale of the Maudsley Obsessive Compulsive Inventory (MOCI) showed negative correlations with the iconic memory scores at all time points.
This study showed that washer OCD patients may have impaired iconic formation and fast iconic decay, which could significantly affect the amount of information transferred to visual memory.
This study showed that washer OCD patients may have impaired iconic formation and fast iconic decay, which could significantly affect the amount of information transferred to visual memory.
In this study, we aimed to investigate the Neurexin 3 gene (NRXN3) polymorphisms in the rs 221473, rs 221497, rs1004212 and rs11624704 regions in relation to nicotine use disorder (NUD) in the Turkish population.
Power analysis indicated that the NUD group and the control group of this study should each comprise 200 participants in the 18-65 year age range. The NUD group consisted of individuals without a psychiatric first axis disorder except for NUD, mental retardation, past head trauma or a neurological disorder, who had smoked minimally10 cigarettes per day for at least 1 year. The control group included individuals without a serious chronic physical illness, a previous psychiatric disorder or mental retardation and who responded "no" to the question "have you ever smoked?" A sociodemographic questionnaire and the Fageström nicotine dependence scale (FNDS) for the NUD group were utilized. Venous blood samples of all participants were taken into tubes containing EDTA (ethylene daimine tetra acetic acid) for DNA extraction. Duplex fluorescence melting curve analysis was used for genotype detection and differentiation.
The individuals carrying the AC allele and the AG allele at the rs11624704 and the rs1004212 regions respectively had a high risk of being addicted to cigarettes.
This is first study investigating the relationship of the NRXN3 gene and nicotine addiction in the Turkish population. It was observed that the risk of NUD in the Turkish population may be related to the Neurexin gene.
This is first study investigating the relationship of the NRXN3 gene and nicotine addiction in the Turkish population. It was observed that the risk of NUD in the Turkish population may be related to the Neurexin gene.
