Wigginswestergaard5624
The dimensional deviation was estimated at 0.31% and the form deviation at 0.165 µm between the Gaussian sphere and the certified ball. Navitoclax The inspection of the manufactured surfaces revealed under-milled areas on the occlusal face, particularly on the anatomical fossae, and an irregular margin limit compared with its smooth design.
A reliable micro-CT evaluation of the dimensional accuracy of a manufactured dental prosthesis compared with the CAD model demonstrated the performance level of CAD/CAM systems. The evaluation reliability was confirmed by the estimation of prior measurement errors. This estimation is essential for the metrological analysis.
A reliable micro-CT evaluation of the dimensional accuracy of a manufactured dental prosthesis compared with the CAD model demonstrated the performance level of CAD/CAM systems. The evaluation reliability was confirmed by the estimation of prior measurement errors. This estimation is essential for the metrological analysis.
The goal of this case series was to evaluate the clinical outcome at the 2-year follow-up of immediately loaded combined screw- and conometric-retained implant-supported full-arch restorations virtually planned using digital scanning technology.
This series included 12 patients presenting hopeless teeth in the maxilla treated with computer-guided flapless implant placement. A total of 72 implants were inserted. All implants were immediately loaded with a complete-arch restoration supported by an intraorally welded framework. Digital scanning technology was used to virtually plan a combined screw and conometric retention of the frameworks. Clinical parameters were assessed at 1 week and at 1, 3, 6, 12, and 24 months follow-up.
The survival rate after 2 years was 98.6%, as one implant failed during the osseointegration period. No major prosthetic complications were observed such as issues with mobility, unscrewed abutments, disconnected conometric copings, and prosthetic fracture. Only one patient registered the chipping of a prosthesis.
Based on the results of the present study, the use of combined screw and conometric retention for fixed immediate restorations properly planned using digital scanning technology seems to be a viable treatment alternative to screw or conometric retention alone for immediately loaded rehabilitations.
Based on the results of the present study, the use of combined screw and conometric retention for fixed immediate restorations properly planned using digital scanning technology seems to be a viable treatment alternative to screw or conometric retention alone for immediately loaded rehabilitations.
The aim of the present study was to compare six different methods of in vivo color matching visual shade matching (3D-Master Linearguide shade guide) performed by 1) a novice practitioner, 2) an expert practitioner, 3) the new Rayplicker spectrometer, 4) the Trios III intraoral scanner, and 5) the Omnicam intraoral scanner compared with 6) the Easyshade V spectrophotometer, which was considered as the reference.
Color matching was performed using the 3D-Master references on the sound maxillary right central incisors of 40 subjects. The study first compared the number of colors found using each of the six methods. The references were then converted to the Commission Internationale de l'Eclairage (CIE) L*a*b* values, from which the difference ?E between either two methods ?was derived. Finally, the L* value was used to compare the luminosity measured by each of the six methods.
The Rayplicker showed the smallest ?E compared with the Easyshade V. The expert found a closer color to the Easyshade V than did the novice, and both were closer to the Easyshade V than the two intraoral scanners. The intraoral scanners showed notable differences compared with the Easyshade V. The intraoral scanners also offered a reduced choice of colors and recorded the highest luminosities compared with the other methods.
Within the limitations of this study, the color matching by the Rayplicker was closest to that of the Easyshade V. The good performance of this new device means that it is a challenging competitor for the Easyshade V. Finally, the new methods based on intraoral scanners were less reliable than the spectrophotometers and the visual shade matching.
Within the limitations of this study, the color matching by the Rayplicker was closest to that of the Easyshade V. The good performance of this new device means that it is a challenging competitor for the Easyshade V. Finally, the new methods based on intraoral scanners were less reliable than the spectrophotometers and the visual shade matching.
Hypoglycemia is a common acute complication of type 1 diabetes (T1D), which may cause seizure, loss of consciousness, temporary motor or sensory impairment. Glucagon administration is an effective way of treating severe hypoglycemia, especially in a free-living setting. Nonetheless, families have difficulties in managing severe hypoglycemia due to their anxiety and challenges in current glucagon administration techniques. The aim of the current study was to explore the associations between the parental fear of hypoglycemia (FoH) and their general anxiety level, in particular, their attitudes towards and thoughts on glucagon administration.
68 parents of children with T1D completed questionnaires assessing background and clinical information, FoH, generalised anxiety disorder (GAD) and parental anxiety for glucagon administration (PAGA).
The results show that the parents of children with T1D had anxiety and fear connected with hypoglycemia and glucagon administration. A structured and practical training on glucagon administration is therefore needed.
The results show that the parents of children with T1D had anxiety and fear connected with hypoglycemia and glucagon administration. A structured and practical training on glucagon administration is therefore needed.
An impressive percentage of biomedical advances were achieved through animal research and cell culture investigations. For drug testing and disease researches, both animal models and preclinical trials with cell cultures are extremely important, but present some limitations, such as ethical concern and inability of representing complex tissues and organs. 3D cell cultures arise providing a more realistic in vitro representation of tissues and organs. Environment and cell type in 3D cultures can represent in vivo conditions and thus provide accurate data on cell-to-cell interactions, and cultivation techniques are based on a scaffold, usually hydrogel or another polymeric material, or without scaffold, such as suspended microplates, magnetic levitation, and microplates for spheroids with ultra-low fixation coating.
This review aims at presenting an updated summary of the most common 3D cell culture models available, as well as a historical background of their establishment and possible applications.
Even though 3D culturing is incapable of replacing other current research types, they will continue to substitute some unnecessary animal experimentation, as well as complement monolayer cultures.
