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lysis reaction, whose content is strongly dependent on the PLA/alcohol feed ratios. The products obtained from the PG reaction was selected as a potential candidate for use as the polyol starting material for preparing highly-elastic PUs. The resulting PU products show a low modulus comparable to rubber materials, with high elongation at break, which is suitable for use as toughness-enhancement agents for other polyesters, or as functional biomaterials. The materials exhibit excellent healing property, and further enhancements in the tensile strength and modulus after heat treatments.Dorzolamide hydrochloride and timolol maleate is a well-established fixed-dose combination for the treatment of glaucoma worldwide. The utilization of simulated biological fluids can give a superior understanding of the release mechanisms and practicable in vivo nature of a dosage form that can improve the predictive potential of in vitro drug release testing. No method has been reported so far for the simultaneous estimation of dorzolamide and timolol in simulated tear fluid. In the present study, a simple, precise, and accurate first-order derivative ultraviolet spectrophotometric method for the routine analysis of dorzolamide and timolol in simulated tear fluid is proposed for in vitro drug release testing. The developed method was validated as per International Conference on Harmonization guidelines Q2 (R1). First-order derivative UV spectrophotometry was successfully applied to separate the overlapping peaks of dorzolamide and timolol by measuring peak amplitude at 251.80 nm and absorbance at 295.00 nm, cular products and help to predict the in vivo performances of ophthalmic preparations.The allocation of resources between storage and somatic growth is an essential physiological phenomenon in animals. Allocation mechanisms have broad theoretical and applied implications. The real-time resource allocation patterns in animals remain to be elucidated, and there is limited understanding of the metabolic mechanisms. We investigated the resource allocation strategy of Rana omeimontis tadpoles. Their ontogenetic fat accumulation began when body weight increased to 30-50 mg, at which time storage had a high priority in resource allocation. Beyond this weight range, somatic growth accelerated but storage investment was maintained, resulting in a positive correlation between body fat index and body weight at the population level. This pattern could be explained by assuming a positive relationship between storage abundance and growth investment, and this was supported by the prioritized increment of body fat to body weight when tadpoles were provided with increased food. At the metabolic level, hepatic fat accumulation was accompanied by upregulated utilization of fat storage, and the tadpoles presented lipid-based energy metabolism. Activating the mobilization of hepatic fat storage promoted somatic growth. In short, the liver is like a reservoir with valves that regulate energy flow for downstream developmental processes. These results provide novel mechanistic insights into resource allocation.This study demonstrated that multi-walled carbon nanotubes (MWCNTs) could mitigate copper oxide nanoparticles (CuO NPs)-induced inhibition to acidogenic metabolism of propionic acid bacteria (i.e., Propionibacterium acidipropionici) by regulating carbon source utilization. CuO NPs severely inhibited the growth of P. acidipropionici, damaged its cell membrane, and down-regulated gene expressions and enzyme activities involved in acidogenic metabolism, thereby decreasing propionate production. However, although MWCNTs had a slightly negative impact on the growth and cell membrane, the gene expressions and catalytic activities were enhanced (glycolysis and pyruvate metabolism), resulting in the improved propionate production. Additionally, the gene expressions and catalytic activities of key enzymes (e.g., tpiA, pgk, PK, OTTAC, etc.) related to acidogenic metabolism were also enhanced by the co-existence of both nanomaterials, thereby promoting propionate production towards P. click here acidipropionici. This work demonstrated that the presence of MWCNTs could affect the inhibition of CuO NPs to fermentation processes via regulating carbon source utilization.Valorization of biomass to olefin or aromatics harbours tremendous practical value due to growing concerns about sustainable production of chemicals. Herein, the olefin or aromatics yields of ex-situ catalytic pyrolysis of pine can be regulated by impregnating Sn on hollow-structured ZSM-5 (M-ZSM-5) and microporous ZSM-5 catalysts in fixed-bed reactor, respectively. Results showed that Sn/ZSM-5 catalyst simultaneously increased medium acidic sites and maintained strong acidic sites, which obtained the maximum carbon yield of aromatics (33.77%) due to enhanced cracking and deoxygenation reactions. In addition, Sn boosted alkylation between olefin and aromatics, generating more alkylbenzene. In contrast, Sn/M-ZSM-5 catalyst produced the highest olefins carbon yield (12.39%) because the reduction of strong acidic sites and microporous volume inhibited the olefin aromatization. Moreover, olefins were easier to desorb from Sn/M-ZSM-5 due to the enhanced mass transfer ability, which weakened the alkylation reactions. The synergistic effect harbours great significance to manipulate the distribution of products.The implementation of anaerobic membrane bioreactor as mainstream technology would reduce the load of sidestream anaerobic digesters. This research evaluated the techno-economic implications of co-digesting sewage sludge and food waste in such wastewater treatment plants to optimise the usage of the sludge line infrastructure. Three organic loading rates (1.0, 1.5 and 2.0 kg VS m-3 d-1) and different strategies to manage the additional nutrients backload were considered. Results showed that the higher electricity revenue from co-digesting food waste offsets the additional costs of food waste acceptance infrastructure and biosolids disposal. However, the higher electricity revenue did not offset the additional costs when the nutrients backload was treated in the sidestream (partial-nitritation/anammox and struvite precipitation). Biosolids disposal was identified as the most important gross cost contributor in all the scenarios. Finally, a sensitivity analysis showed that food waste gate fee had a noticeable influence on co-digestion economic feasibility.