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This study examines the impact of economic and financial activities on air pollution in China using prefecture-level panel data from 2004 to 2015. Recruiting the air quality index (AQI) as a measure of overall air quality in Chinese cities, we find that industrial production, financial development, and economic integration lead to higher overall air pollution. Nevertheless, efficiency in urban planning through public transportation and population density alleviates this environmental degradation. SB715992 A closer look into the two main air pollutants in China, sulphur dioxide and dust, further highlights the complexity of the issue. link2 We find that trade openness reduces both sulphur dioxide and dust emissions, whereas financial development reduces sulphur dioxide emissions but increases dust in Chinese cities. Our findings are of particular interest to policymakers when devising environmental policies in support of sustainable economic development.Value addition of agro products improves the livelihood opportunities for rural farmers. Cold Storage is one of the techniques to improve the shelf life of agro product. With the increase in the utilization of refrigeration and air cooling using vapour compression refrigeration technology, global warming and ozone depletion due to the refrigerants have also been increased. So, to overcome this problem, several restrictions were placed on the refrigerant by the United Nations Framework Convention on Climate Change (UNFCCC). There is no way to slow down the growth of this technology, so the focus should be shown on finding an alternative. Various studies have been carried out on an alternate refrigeration system. This paper attempts to study the power quality challenges in the conventional vapour compression system. A comparative analysis of vapour compression refrigeration (VCR) and vapour absorption refrigeration (VAR), power factor analysis and temperature measurement on both technologies has also been carried out and reported.The phytoremediation potential of Myriophyllum spicatum L. has been well documented for bulk-sized heavy metals, including zinc (Zn). However, there is no information on the removal efficiencies of this aquatic macrophyte for zinc oxide nanoparticles contaminated waters. Therefore, the present study was aimed to compare the removal efficiency of M. spicatum in two different media tap water and pond water. Results were evaluated by comparing percentage (%) removal and goodness-of-fit to regression models. Plants were exposed to 0.8 and 2 ppm nano-sized Zn for 1, 4, and 7 days. The zinc concentrations were monitored using ICP-MS. The %removal in tap water ranged between 29.5 and 70.3%, and slightly higher in pond water. Modeling results confirmed that there was a strong relationship between removal performance and exposure duration. Time-dependent removal shows that %removal shows no further progress after 4 days. Our results also indicate that planktonic communities in pond water might play an important role in the fate of ZnO NPs.Treating biosolids from industrial, urban, and agricultural plants produces high amounts of water. After organic pollutants and non-essential heavy metals have been removed, these wastewaters are still rich in trace elements such as zinc (Zn), copper, or manganese (Mn) and have high conductivity and extremely variable pH. In this study, an isolated Chlorella sp. strain was grown for 21 days in nutrient solutions enriched with known amounts of Zn or Mn to obtain concentrations three (4.0 mg L-1)- and six (1.0 mg L-1)-fold higher than the basal medium levels, respectively, and over the limits permitted in aquatic environments. The green alga exhibited high tolerance to Zn and Mn, with the maximum abatement of Zn (28-30%) and Mn (60-63.5%) after 14 and 7 days of culture, respectively. Mn stimulated the growth rate and biomass production of Chlorella, which showed the highest carbon levels just in the first week. In both treatments, the nitrogen and protein contents remarkably increased. The photosynthetic pigments increased until the 14th day, with a higher extent in the Zn-enriched solution. An increasing photochemical efficiency was observed after 7 days of treatment, when the microalgae grown in Zn- and Mn-enriched solutions showed a slightly higher maximum photochemical efficiency than control. The autotrophic and controlled growth system adopted was designed to monitor the dynamic balance of Zn and Mn contents in the solutions and in the algal biomass. This system has proved to be useful in identifying the optimal nutritional conditions of the microalgae, along with the optimal temporal patterns of both metal biosorption capacity for water remediation and element bioaccumulation in the algal biomass.Immense epidemiological studies have been indicated about adverse effects of the welding fumes on the health of the welders, especially respiratory problems and other physiological disorders. The different types of welding mechanisms produce aerosols/fumes that contain different metals including chromium (Cr) and manganese (Mn). In the present study, the welders of two age groups (adolescents and adults) were selected; simultaneously the age-matched adolescents and adults belong to nonindustrial area as referents/control subjects. Biological samples (scalp hair) were collected from welders and referents, along with analyzed for Cr and Mn by electrothermal atomic absorption spectrometer, prior to acid digestion. To evaluate the occupational exposure on the health of the workers, the clinical features and biochemical parameters of selected population (exposed and non-exposed age-matched groups) were also carried out. The resulted data indicated that the concentrations of Mn and Cr were significantly higher in scalp hair samples of welders as compared to referent subjects (p  50 years, might be due to long time exposure of welding fumes contains different toxicant especially Mn in ill ventilation system of workshops.In view of the sector-wide effect of the nCOVID-19 pandemic in the USA and the probable effect on certain over-the-counter (OTC) pharmaceutical products, the current study examined potential inflation in the pharmaceutical industry arising from the pandemic-related uncertainty. In this case, the USA's producer price indexes vis-à-vis inflation of the immune-related pharmaceutical items multivitamin, vitamins nutrients and hematinic (V-N-H), other vitamins (other-V), antidepressant, and antidiabetic were examined alongside the uncertainties arising from the world pandemic and economic policy. link3 Thus, the (Diebold and Yilmaz in Int J Forecast 28(1) 57-66, 2012) result implied that the world pandemic uncertainty contributed a significantly huge shock to the examined pharmaceutical compounds, thus affirming the vulnerability of certain pharmaceuticals to pandemic-related uncertainty. The total spillover increased from 34.2% (with economic policy uncertainty) to 47.6% (when pandemic uncertainty is incorporated). In specific, there are negative net spillovers from the multivitamins, other vitamins, antidiabetic, and antidepressant especially due to high pandemic and economic policy uncertainties. However, the statistical evidence implied that higher uncertainty arising from the pandemic is responsible for the severity of shock received by the indicated pharmaceutical products as against economic policy uncertainty. Thus, a relevant policy inference is posited from the result of the study.The study deals with the effects of herbicides (metribuzin, tribenuron-methyl, fenoxaprop-P-ethyl) and fungicides (tebuconazole, epoxiconazole, azoxystrobin) applied to soil as free pesticides or as slow release formulations embedded in a biodegradable composite matrix on the structure of the soil microbial community. The matrix consisted of a natural biopolymer poly-3-hydroxybutyrate [P(3HB)] and a filler-one of the natural materials (peat, clay, and wood flour). The soil microbial community was characterized, including the major eco-trophic groups of bacteria, dominant taxa of bacteria and fungi, and primary P(3HB)-degrading microorganisms, such as Pseudomonas, Bacillus, Pseudarthrobacter, Streptomyces, Penicillium, and Talaromyces. The addition of free pesticides adversely affected the abundance of soil microorganisms; the decrease varied from 1.4 to 56.0 times for different types of pesticides. The slow release pesticide formulations, in contrast to the free pesticides, exerted a much weaker effect on soil microorganisms, no significant inhibition in the abundance of saprotrophic bacteria was observed, partly due to the positive effects of the composite matrix (polymer/natural material), which was a supplementary substrate for microorganisms. The slow release fungicide formulations, like the free fungicides, reduced the total abundance of fungi and inhibited the development of the phytopathogens Fusarium and Alternaria. Thus, slow release formulations of pesticides preserve the bioremediation potential of soil microorganisms, which are the main factor of removing xenobiotics from the biosphere.Pyrimidine analogues can be considered as prodrugs, like their natural counterparts, they have to be activated within the cell. The intracellular activation involves several metabolic steps including sequential phosphorylation to its monophosphate, diphosphate and triphosphate. The intracellularly formed nucleotides are responsible for the pharmacological effects. This review provides a comprehensive overview of the clinical studies that measured the intracellular nucleotide concentrations of pyrimidine analogues in patients with cancer. The objective was to gain more insight into the parallels between the different pyrimidine analogues considering their intracellular pharmacokinetics. For cytarabine and gemcitabine, the intracellular pharmacokinetics have been extensively studied over the years. However, for 5-fluorouracil, capecitabine, azacitidine and decitabine, the intracellular pharmacokinetics was only very minimally investigated. This is probably owing to the fact that there were no suitable bioanalytalisation is useful to achieve these concentrations.Formation of photosynthetic complexes leads to a higher demand for Fe-S clusters. We hypothesized that in the facultative phototrophic alpha-proteobacterium Rhodobacter sphaeroides expression of the isc-suf operon for Fe-S cluster formation may be increased under conditions that promote formation of photosynthetic complexes and that, vice versa, lack of the IscR regulator may also affect photosynthesis gene expression. To test this hypothesis, we monitored the activities of the isc-suf sense and anti-sense promoters under different growth conditions and in mutants which are impaired in formation of photosynthetic complexes. We also tested expression of photosynthesis genes in a mutant lacking the IscR regulator. Our results are not in agreement with a co-regulation of the Isc-Suf system and the photosynthetic apparatus at level of transcription. We provide evidence that, coordination of the systems occurs at post-transcriptional levels. Increased levels of isc-suf mRNAs under conditions promoting formation of photosynthetic complexes are due to higher RNA stability.

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