Knowlesmcguire2923

5; 95% CI 2.42-289.4; p=0.007).

IVF-ET affects the antenatal diagnosis of PAS using MRI.

IVF-ET affects the antenatal diagnosis of PAS using MRI.

To evaluate the role of histogram analysis of apparent diffusion coefficient (ADC) maps from diffusion-weighted imaging (DWI) in the differentiation of follicular thyroid carcinoma (FTC) from follicular adenoma (FA) in nodules indeterminate on ultrasound-guided core needle biopsy (USCNB).

This study was performed with institutional review board approval. Seventeen patients who were planned to undergo diagnostic lobectomy for an indeterminate thyroid nodule (atypical of unknown significance/follicular lesion of undetermined significance [AUS/FLUS] or suspicious for follicular neoplasm/follicular neoplasm [SFN]) on USCNB were enrolled prospectively. All patients underwent DWI on the day before surgery. Histogram parameters were derived from ADC values obtained from the whole extent of the tumours. The parameters were compared with the final diagnosis based on histopathological examination after surgery. The accuracy of the parameters in differentiating FTC from FA was evaluated using receiver operating characteristic (ROC) curve analysis.

Twelve patients were confirmed as having FA and five patients as having FTC. Histogram parameters including the 10

(ADC

), 25

(ADC

), and 50

(ADC

) percentiles of the ADC values were significantly lower in FA than in FTC (p < 0.05, all). ROC curve analysis revealed that ADC

resulted in the highest AUC (0.867; confidence interval, 0.616-0.980), with a cut-off value of 0.352×10

mm

/s.

Histogram parameters from ADC maps could differentiate FTC from FA effectively in indeterminate nodules on USCNB, with ADC

being the most promising parameter.

Histogram parameters from ADC maps could differentiate FTC from FA effectively in indeterminate nodules on USCNB, with ADC25 being the most promising parameter.With growing strain on mental health services, greenspace interventions could be a promising addition to current health and social care provisions as they have the potential to be widely accessible for people within their own communities and used alongside a variety of treatment plans. Despite promising progress in greenspace research, the underlying mechanisms and processes of greenspace interventions are still unclear. Without knowing these it is impossible to understand why programmes work and how best to replicate them. To address this gap this review uses realist methodology to synthesise the international evidence for greenspace interventions for mental health in both clinical and non-clinical populations. Forty-nine full text articles are included in the review and the underlying contexts, mechanisms, and outcomes of the interventions identified and refined into an original overriding theory under three themes of Nature, Individual Self, and Social Self. The interaction of these three factors represents a new conceptual framework for greenspace interventions for mental health and shows what works, for whom, and in what circumstances. The findings of this review are not only theoretically novel but they also have practical relevance for those designing such interventions including the provision of recommendations on how to optimise, tailor and implement existing interventions.Foreclosure sales permitted investors to purchase large volumes of low-cost residential properties after the last financial crisis, reshaping patterns of property ownership in low-income housing markets across the US. This study links post-foreclosure property acquisitions by investor landlords to subsequent lead poisoning cases among children under age six living in Detroit, Michigan. We find that the odds of exhibiting elevated blood lead levels (≥5 μg/dL) are higher for children living in investor-owned homes purchased through tax foreclosure sale. These findings highlight the potential for property speculation in post-foreclosure housing markets to exacerbate severe and racialized burdens of excess lead toxicity in low-income communities.Health researchers increasingly recognize the influence of spatial stigma, or negative reputation of place, as a social determinant of health. Drawing from a New Haven-based cohort study (n = 251), we assessed the relationships between spatial stigma, self-rated health, and psychological distress using generalized estimating equation models. Adjusting for neighborhood-level poverty and racial composition, those who perceived living in spatially stigmatized neighborhoods were significantly more likely to report severe psychological distress compared to those that did not perceive their neighborhoods to be stigmatized (B = 1.09, CI 0.31, 1.87). Our findings contribute to a growing body of literature that suggests that socially constructed meanings of place may influence health.We designed a retrospective cohort study for exploring the impact of municipality-level income inequality, based on the Gini 1986, 2004 indices, on all-cause old-age mortality among the older Swedish population during 2005-2009. We controlled for the confounding effects of individual and regional correlates and the lag effects of inequality by using multilevel logistic regression. The effects of income inequality were not consistent across age cohorts and, among the youngest cohorts, were negligible. This study reiterates that individual-level economics rather than the immediate or lagged effects of income inequality matter more for old-age mortality, even after controlling for individual and regional factors.Various factors have been associated with the ongoing high prevalence of malaria in Ghana. Among these are poor sanitation, low socioeconomic status (SES), building construction and other proximate micro environmental risks, and individual behaviors. What makes the curbing of malaria more challenging, is that for many of the most impacted areas there is little data for modeling or predictions, which are needed, as risk is not homogenous at the sub-neighborhood scale. In this study we use available local surveillance data combined with novel on-the-ground fine scale environmental data collection, to gain an initial understanding of malaria risk for the Teshie township of Accra, Ghana. Mapped environmental risk factors include open drains, stagnant water and trash. Overlaid onto these were clinical data of reported malaria cases collected between 2012 and 2016 at LEKMA hospital. We then enrich these maps with local context using a new method for malaria research, spatial video geonarratives (SVGs). These SVGs provide insights into the underlying spatial-social patterns of risks, to reveal where traditional data collection is lacking, and how and where to develop local intervention strategies.This study examines (1) the association between the neighborhood social environment and obesity among adolescents, (2) whether physical activity, screen time, and short sleep mediates this association, and (3) examine sex differences. Participants (n = 12,692; age 11-19 years old) came from Waves I and II of the National Longitudinal Study of Adolescent to Adult Health. Neighborhood social disorganization and socioeconomic status (NSES) measures were associated with obesity adjusting for sex, race, age, parental education, and urbanicity. Screen time mediated NSES and obesity. Very short sleep duration ( less then 6 h) mediated social disorganization and obesity among females only. Findings suggest improving neighborhood social conditions may reduce the risk for obesity.In this exploratory sequential mixed-methods study, interviews with 125 adults aged 55-92 (mean age 71) living in the Minneapolis (Minnesota) metropolitan area suggested that eateries, including coffee shops and fast-food restaurants, represent popular neighborhood destinations for older adults and sources of wellbeing. TPX0046 Thematic analysis of how older adults perceived and utilized local eateries included sites of familiarity and comfort; physical and economic accessibility; sociability with friends, family, staff, and customers; and entertainment (e.g., destinations for outings and walks, free newspapers to read). To test the hypothesis that these sites, and the benefits they confer, are associated with cognitive welfare, we analyzed data from urban and suburban community-dwelling participants in the Reasons for Geographic And Racial Differences in Stroke (REGARDS) study, a national racially diverse sample of older Americans followed since 2003 (n = 16,404, average age at assessment 72 years). Results from multilevel linear regression models of these data demonstrated a positive association between kernel density of local eateries and cognitive functioning, which corroborated qualitative findings. Taken together, these results complicate our understanding of casual eatery settings as possible sites of wellbeing through social interaction and leisure activities. Results prompt further research investigating whether and how retail food environments can serve as community spaces for older adults that may help buffer against cognitive decline.This paper explores how a peer-and street-based naloxone distribution program (Bmore POWER) reshapes narratives and practices around drug use and harm reduction in an urban context with an enduring opioid epidemic. Data collection included observations of Bmore POWER outreach events and interviews with peers. Bmore POWER members create a sense of community responsibility around overdose prevention and reconfigure overdose hotspots from places of ambivalence to places of grassroots action. It expands a harm reduction approach to Black communities that have not traditionally embraced it and that have been underserved by drug treatment programs. Policy makers should consider ways to use peers grounded in specific communities to expand other aspects of harm reduction, such as syringe and support services.The ability to move about the community safely and easily plays a key role in the lives of people who use mobility devices. This study explored how personal characteristics, mobility device use, transportation, and environmental factors affected the size of their activity spaces (i.e., daily path area). Seventy-eight people who used manual wheelchairs, power wheelchairs, scooters, walkers, canes, and/or crutches tracked their movements in the community using a geographical positioning system device over a 7-day period. Participating in productive activities, walkability, the interaction between access to a vehicle and walkability, seasonality, and location helped to explain 43% of the variability in daily path area. The type of mobility device used and years using a device were associated with activity space size in bivariate analysis but not significantly significant in the regression model. The findings underscore the complex challenges that people who use mobility devices face moving about the community. Implications for researchers and transportation planners are discussed.Gender-based violence can include, but is not limited to, domestic violence, intimate partner violence, rape, and intimate partner homicide. It is well-established that gender inequality is the main driver of gender-based violence. However, little work has attempted to unpack how gender-based violence perpetuates within the neighbourhood context, and whether 'liveability' attributes might intersect with gender inequality and violence. We systematically reviewed quantitative evidence examining associations between gender-based violence and several liveability neighbourhood-level factors. MEDLINE (Ovid) and Scopus databases yielded 1822 potentially relevant articles. 50 articles met inclusion criteria. Neighbourhood social capital was most consistently associated with reduced gender-based violence. Few studies examined built environment attributes (e.g. gambling venue densities, access to services). Future research is needed to more deeply examine how combinations of salutogenic or pathogenic neighbourhood attributes may reinforce or prevent violence.