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05; sensitivity 44.40%; specificity 84.20%), higher radiographic assessment of lung oedema score (RALES) on the day of starting NIV (p less then 0.009; sensitivity 70.40%; specificity 73.75%), higher length of NIV (p less then 0.014; sensitivity 48%; specificity 84.10%) and higher urea on the day of starting NIV (p less then 0.004; sensitivity 70.44%; specificity 73.72%) Conclusion NIV treatment in COVID-19 critically ill patients has a high failure rate. In addition to respiratory parameters, dyspnoea, higher RALES, higher length of NIV and increased urea value could predict NIV failure. These factors should be considered in treatment decision making.Aim To present a unique case of a 22-year-old male patient with symptomatic epilepsy manifestation on a background of neurocysticercosis (NCC). Methods An Indian student in Kharkiv, who lived in rural parts in India, presented with sudden episodes of seizure followed by severe headaches. Laboratory analyses and neurological status (MRI) were performed. Results Neurological status of the patient revealed nystagmus and difficulty in performing co-ordination tests. General analysis of blood showed raised eosinophil count to 8%. The MRI showed a few small conglomerating peripherally enhancing thick-walled infective granulomas in left frontal lobe with extensive surrounding oedema in the left fronto-parietal lobe. The patient was treated with albendazol, levipil, methylprednisolone and pantoprazole. Clinical symptoms and subsequent MRI showed improvement. Conclusion Neurocysticercosis is often misdiagnosed in the early stages, which leads to adverse outcomes. Although seizures are the most common clinical manifestation, it is a symptom that is not found in majority of the patients. The NCC of adult onset accompanying epileptic seizures is not well studied and a link between the helminthic invasion, epilepsy and psychiatric conditions needs to be established. This disease is potentially eradicable with wellplanned eradication programs targeting all stages of Taenia solium life cycle.Aim To measure a calibre of radial and ulnar septocutaneous perforators at the anterior forearm, and to count its number in proximal, middle and distal thirds. Methods The study was conducted on 50 fresh amputated forearms (trauma, tumours) in the period between January 2012 and December 2021. Forearms were collected from several hospitals in Belgrade, and analysed at the Institute of Anatomy, Medical School, University of Belgrade, Serbia. Injection of ink-gelatin and fine dissection of autopsy material was performed on 30 forearms, and corrosion method with injecting methyl methacrylate for 3D analysis on the other 20 forearms. Results A mean calibre of septocutaneous perforators on the radial artery was 0.53±0.46 mm (0.2-0.85). Averagely, there were 8.1 radial artery septocutaneous perforators - two perforators on the proximal third, 3.7 on the middle third, and 2.7 on the distal third. The mean calibre of ulnar artery perforators was 0.65±0.35 mm (0.18-1.8). The average number of septocutaneous perforators of the ulnar artery was 5.6; 1.2 on the proximal third, two on the middle third, and 2.2 on distal third. Conclusion Determination of the origin, calibre and spreading directions of the arterial septocutaneous perforators on the anterior forearm provide quantification of data about arborisation of radial and ulnar septocutaneous perforators at the anterior forearm. Clinical relevance of those anatomical data is in defining of safe locations and dimensions of forearm fasciocutaneous flaps in plastic surgery.Aim To explore the possibility of C-reactive protein (CRP) and haemoglobin (Hb) in prediction and risk assessment of acute kidney injury (AKI) among preterm newborns. This is believed to be closely related to the incidences of AKI, and could be the most affordable in early detection of AKI. Methods A case control study was carried out at Dr Hasan Sadikin Hospital in Bandung with a total of 112 preterms divided into two groups with and without AKI based on the neonatal KDIGO (Kidney Disease Improving Global Outcomes). CRP and creatinine serum were measured within 6 hours and at 72-96 hours after birth. The routine blood count included haemoglobin, haematocrit, leucocyte, and thrombocyte in the first 24 hours of life. Results CRP increase was the most influential factor for AKI with sensitivity of 80.6% and specificity of 60.2%. An increase in CRP >0.04 had an aOR (95% CI) of 5.64 (1.89-16.84). Haemoglobin 0.04 and level Hb less then 14.5 g/dL showed acceptable as an early warning for AKI in preterm newborns.The article is devoted to the history of the emergence and functioning of departmental medical statistics in the German states in 1800-1871. The authors, on the basis of the analysis of German historiography, identify main actors, goals, methods of administration and representation of health statistics. Starting from the specifics of German terminology concerning the umbrella term "medical statistics" ("medizinische Statistik", "Medizinalstatistik", "sanitäre Statistik", "Gesundheitsstatistik"), the authors elaborate in detail on the cases of the Bavarian and Prussian kingdoms. By the beginning of the XIX century, the mechanisms of building modern state were started up in these countries. In its functioning, it was primarily based on statistical surveys of people and territories. The gradual institutionalization of medical statistics, its complexification and enhancement are considered in the context of state bureaucratic system reforming. The analysis of historical research results permitted to generate cumulative picture of becoming and development of medical statistics in Bavaria and Prussia. The study of transformation of reporting forms allowed to see how the bureaucratic institutions, by means of statistical methods, sought to rate the "death" and "health" of population.The article analyzes the scientific and political aspects of the biography of Nikolai Konstantinovich Kulchitsky (1856-1925). He was not only the last tsarist minister of education, but also the sole medico at this high position. R788 in vitro The scientific achievements of professor histologist from Kharkov have proved to be in great demand in the XXI century not only in neuroendocrinology, but in oncology and pulmonology too. The authors analyzed the stages and conditions of the administrative career of the conservative Kulchitsky heading large educational districts during five years and two ministerial months in the beginning of 1917. He managed to do not a little for development of school hygiene and sanitation in the Kazan and Petrogad educational districts, including in conditions of the world war. The meaningful for the particular epoch the combination of medical and social aspects of activities of gifted researcher medico deserves a special attention and comprehensive study.