Jonassenfeldman5054
Tea consumption may contribute to the management of blood pressure; however, evidence from longitudinal studies is lacking. This study aimed to examine the relationship between habitual tea consumption and trajectories of systolic blood pressure in a community-based sample of Chinese adults aged 60 years or older.
A prospective cohort of 3870 participants was investigated from 2014 to 2018. Trajectories of systolic blood pressure were identified using latent mixture modeling with the Proc Traj procedure. Multiple logistic regression models were fitted to explore associations between tea consumption habits and trajectories of systolic blood pressure.
In the overall sample, participants were less likely to be habitual tea drinkers if they were in the "moderate-stable" (144.4-149.9 mm Hg), "moderate-increasing" (157.2-180.0 mm Hg), and "elevated-increasing" (184.7-209.8 mm Hg) groups as compared to those in the "low-stable" group (125.3-130.0 mm Hg). The "elevated-decreasing" group (170.7 - 167.2 mmHg) consistently showed no significant difference in the likelihood of habitual tea drinking as compared to the "low-stable" group.
This community-based prospective study indicated that habitual tea consumption was associated with relatively favorable long-term systolic blood pressure statuses.
This community-based prospective study indicated that habitual tea consumption was associated with relatively favorable long-term systolic blood pressure statuses.Rapid environmental change due to climate change impacts Inuit mental wellness by altering the relationships between people, place, livelihoods, and culture. Little is known, however, about how fluctuations in weather contribute to the experience of place and the connection to mental wellness in Inuit communities. This study aimed to characterize the importance of changes in weather among Inuit, and how these changes influence mental health and wellness in the context of climate change. Data were drawn from a community-driven and Inuit-led study in the Nunatsiavut region of Labrador, Canada. In-depth interviews (n = 116 people) were conducted between November 2012 to May 2013 in the five Nunatsiavut communities. Qualitative data were thematically analyzed using a constant comparative method. AMG 232 mw Results indicated that weather impacted mental wellness through three key pathways 1) shaping daily lived experiences including connection to place and other determinants of wellbeing; 2) altering mood and emotion on a transient basis; and 3) seasonally influencing individual and community health and wellbeing. These results demonstrate the immediate role weather has in shaping mental wellness in Nunatsiavut. In turn, this understanding of the climate-mental wellness relationship points to multiple pathways for action on climate adaptation policy and programming, and underscores the need for more culturally-specific and place-based investigations to appropriately respond to the mental health impacts of climate change.Breast cancer is the most common malignancy in women worldwide, with a relatively high proportion of patients experiencing resistance to standard treatments. Cellular immunotherapy (CI), which is based on the extraction, modification, and re-infusion of the patient's immune cells, is showing promising results in these patients. Among CI possible approaches, adoptive cell therapy (ACT) and dendritic cell (DC) vaccination are the most comprehensively explored in both primary/translational research studies and clinical trials. ACT may include the use of tumor-infiltrating lymphocytes (TILs), T cell receptor (TCR)-, or chimeric antigen receptor (CAR)-engineered T-cells. There are indications suggesting that a biomarker-based approach might be beneficial in effectively selecting breast cancer patients for CI. Here, we sought to provide the current knowledge of CI in breast cancer, focusing on candidate biomarkers, ongoing clinical trials, limitations, and immediate future perspectives.
Residential greenness may prevent overweight/obesity, but the matter has not been investigated among middle-aged and older adults in China. This study 1) assessed associations between residential greenness and markers of adiposity among middle-aged and older Chinese adults and 2) investigated physical activity, sedentary behaviours, particulate matter (PM) with a diameter of <2.5μm (PM
) concentrations, and perennial mean temperature as mediators of the associations.
We used data from the World Health Organization's Study on Global Ageing and Adult Health (SAGE) between 2007 and 2010. Overweight/obesity and abdominal obesity were measured by body mass index and waist circumference. Exposure to neighbourhood greenness was measured by the normalized difference vegetation index (NDVI). Multilevel structural equation models were fitted to investigate the associations between neighbourhood greenness, the four potential mediators, and the prevalence of overweight/obesity and central obesity.
The results sith lower odds of overweight/obesity and abdominal obesity among middle-aged and older Chinese adults. However, underlying mechanisms explaining these associations remain unclear requiring longitudinal studies and natural experiments.
Hand hygiene is an efficacious behaviour to prevent community-associated infections. Estimates of the proportion of populations who wash their hands have indicated limited compliance. While biases of self-report items for hand hygiene, such as the tendency to overestimate one's behaviour, represent a limitation, direct survey questions remain important. This study aims to compare indices of handwashing compliance based on single vs. combined handwashing attributes, i.e., its frequency, technique, and duration.
Data of a representative survey on hygiene and infection control by the German Federal Centre for Health Education were analysed. In a cross-sectional, computer-assisted telephone interview design, the resident population in Germany aged 16-85 years was surveyed in 2012. For handwashing, duration, frequency in different situations, and technique (use of soap, washing interdigital spaces, and drying hands) were self-reported. Self-reports were rated as (non-)compliant based on national recommendations and combined into single- and multi-attribute indices.
