Valdezdahlgaard4245

In Jordan, women experience considerable levels of different types of violence. The emerging data from different countries indicate that intimate partner violence (IPV) has intensified since the COVID-19 outbreak. The main purpose of the current study is to find out whether there is any difference in the incidence of IPV during and before the COVID-19 pandemic quarantine and whether any sociodemographical factors are related to the incidence of IPV against pregnant women during quarantine. A cross-sectional, correlational design was in this study. The snowball sampling technique was adopted to select the participants, which produced a nonrepresentative sample of 215 pregnant women. The participants completed the Arabic version of the World Health Organization's Domestic Violence Questionnaire Screening Tool (DVQST). We found that women were exposed to different types of IPV before and during the quarantine. The most prevalent form of IPV was control and humiliation (n 172, 80%) and the least prevalent was sexual violence ((n 33, 15.3%), (n 24, 11.2%), respectively). However, there were statistically significant lower DVQST scores during the COVID-19 quarantine than before the quarantine. All types of IPV are significantly correlated with each other and with relationship problems (marital conflict, verbal fighting, understanding each other). While the findings are not generalizable to the general population of pregnant women in Jordan because the sample consisted only of women of high socioeconomic status due to the use of a nonprobability sampling technique, national campaigns should be developed and implemented in order to reduce IPV and change community behaviors and attitudes toward violence against women. It is also recommended that policymakers develop plans to help pregnant women during quarantine by, for example, training care providers on how to access vulnerable women.

Linn. (Pandanaceae) seed extract is known to have antioxidant activities. However, the potential hepatoprotective effect is still unclear.

To investigate the hepatoprotection aspect of

methanol extract towards paracetamol-induced rats.

Thirty male Sprague-Dawley rats were randomly divided into six equal groups one group served as the healthy control and five groups with hepatotoxicity (hepatotoxic control and 4 treatment groups). The oral treatment of paracetamol-induced hepatotoxicity of 3 g/kg using three different concentrations of

(300, 600 and 900 mg/kg), and silymarin (200 mg/kg) groups were administered once a day for 14 days. Enzyme activities and protein levels in serum were determined in rats at the end of the treatments. The histopathology of rat livers was observed under an electron microscope with 10× magnification.

significantly decreased the serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), alkaline phosphatase (ALP) and γ-glutamyl transferase (GGT) activities in induced-paracetamol rat serum (

 < 0.05). Moreover,

significantly decreased total bilirubin and direct bilirubin levels (

 < 0.05). It significantly blocked the decline of serum albumin and protein levels (

 < 0.05). Histopathological changes amplified paracetamol-induced liver damage and the hepatoprotective effect of

in the liver.

improved the hepatoprotective effect in a concentration-dependent manner by reducing related hepatic enzyme and protein markers, suggesting as a useful agent in hepatotoxicity treatment, and it can be generalized to a broader study population in different hepatotoxic animal models.

Pandanus odoratissimus improved the hepatoprotective effect in a concentration-dependent manner by reducing related hepatic enzyme and protein markers, suggesting as a useful agent in hepatotoxicity treatment, and it can be generalized to a broader study population in different hepatotoxic animal models.Introduction After chronic impairment of the right dominant hand, some individuals are able to compensate with increased performance with the intact left nondominant hand. check details This process may depend on the nondominant (right) hemisphere's ability to access dominant (left) hemisphere mechanisms. To predict or modulate patients' ability to compensate with the left hand, we must understand the neural mechanisms and connections that underpin this process. Methods We studied 17 right-handed healthy adults who underwent resting-state functional connectivity (FC) magnetic resonance imaging scans before 10 days of training on a left-hand precision drawing task. We sought to identify right-hemisphere areas where FC from left-hemisphere seeds (primary motor cortex, intraparietal sulcus [IPS], inferior parietal lobule) would predict left-hand skill learning or magnitude. Results Left-hand skill learning was predicted by convergent FC from left primary motor cortex and left IPS onto the same small region (0.31 cm3) in the right superior parietal lobule (SPL). Discussion For patients who must compensate with the left hand, the right SPL may play a key role in integrating left-hemisphere mechanisms that typically control the right hand. Our study provides the first model of how interhemispheric functional connections in the human brain may support compensation after chronic injury to the right hand.Two-thirds of newly diagnosed cases of diffuse large B-cell lymphoma (DLBCL) are cured with R-CHOP, an immunochemotherapy regimen that has been the standard of care for almost two decades. Ongoing molecular characterization of DLBCL has revealed a heterogeneous disease comprised of multiple subtypes based on putative cell of origin or somatic mutations with unique oncogenic signaling pathways. The door has been opened to the use of novel agents that target the specific molecular vulnerabilities of DLBCL, but despite this, multiple randomized studies have not identified a suitable drug 'X' to combine with R-CHOP. This report will review recent attempts to add individual novel agents to R-CHOP in the mission to improve frontline treatment for DLBCL and discuss promising ongoing studies. It will offer potential strategies to explore when designing future clinical trials, including exploiting synergy between multiple novel agents.