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Conclusions The obtained data is promising for the search of effective means of correction of anemic syndrome in patients with ankylosing spondylitis.

Introduction The lumbar lordosis angle measured by radiology under normal conditions is between 135-1400. Any deviation from the values is associated with a change in static-dynamic loads and should translate into a change in bone tissue within the lumbar-sacral border, which results from a change in the distribution of load forces acting on individual parts of the vertebral bodies. The aim To determine the relationship between individual variants of lordosis (hypolordosis, hyperlordosis, norm) and the general density of the spongy part of individual vertebral bodies and in selected zones of the lumbosacral zone (L5 / S1).

Material and methods The study group was a population of women over 50 (n = 277), it was divided into three subgroups, i.e. women with normal, shallow and deepened lordosis. In the sagittal view, the density of vertebral bodies from L1 to S1 was assessed.

Results The difference in the overall density of individual stems between normal lordosis and extreme values was significant (p≥0.05) only for the L1, L2 and S1 vertebrae, whereas in the case of an excessive lordosis angle, the density of spongy bone tissue showed significant differences for all measurement points.

Conclusions Deviations from the correct values of the lumbar lordosis angle result in a change in compressive and shear forces, which is reflected in the reconstruction of bonetissue. This can be a clue to differentiate the physiotherapy program of women reporting back pain - depending on the size of the lumbar lordosis angle.

Conclusions Deviations from the correct values of the lumbar lordosis angle result in a change in compressive and shear forces, which is reflected in the reconstruction of bonetissue. This can be a clue to differentiate the physiotherapy program of women reporting back pain - depending on the size of the lumbar lordosis angle.

The aim is to establish the features of morphological and morphometric changes in the skin of guinea pigs in erythemal, early post-erythemal and late post-erythemic periods after local ultraviolet irradiation.

Materials and methods Studies were conducted on 54 albino guinea pigs weighing 400-500 g. Ultraviolet erythema was caused by irradiation in 1 minimum erythemal dose. The control group included intact guinea pigs. After 2, 4 hours, on the 3rd, 8th, 15th, 21st, 28th day, the fragments of the irradiated skin were investigated using histochemical and morphometric methods.

Results After 2, 4 hours after irradiation, dyscirculatory changes in the skin develop. By the 3rd day of the experiment a morphological picture of acute inflammation in the epidermis and dermis develops, apoptotic keratinocytes appear (sunburn cells), which is accompanied by thickening of the epidermis and an increase in the density of fibroblasts. By the 8th day proliferative-hyperplastic and degenerative changes begin to prevail, including dystrophic nature, the thickness of the epidermis and the density of fibroblasts reach a maximum. In the long term, on the 15-28th day, dystrophic changes of the epidermis, dyskeratosis, changes in the number and structure of elastic fibers with an increase in uneven fibrosis, collagenization processes and the development of sclerotic changes, as well as a significant thickening of the epidermis, an increase in the density of fibroblasts are observed.

Conclusions The data obtained indicate pronounced morphofunctional changes in the skin in the zone of local ultraviolet irradiation observed throughout the entire observation period.

Conclusions The data obtained indicate pronounced morphofunctional changes in the skin in the zone of local ultraviolet irradiation observed throughout the entire observation period.

The aim of this work was to study the hormonal status androgen-dependent indicators of the ejaculate, spermatogram parameters and liver transaminases in the blood of the infertile males for the treatment of arginine, carnitine and betaine.

Materials and methods The parameters of spermograms, the levels of testosterone, estradiol, alanine aminotransferase and aspartate aminotransferase in the blood, and concentration of fructose in the ejaculate of 31 men with idiopathic pathospermia before and after using the L-Betargin, which contains 1 gram of arginine, 300 mg of L-carnitine and 1 gram of betaine.

Results It is shown that after treatment there is an increase of sperm concentration and their motility, increase the level of fructose in the ejaculate. It is established that the positive effect on spermatogenesis, L-Betargin associated with activation of endocrine function of the testes, improving the androgen-estrogen balance and functional state of the liver in men with infertility.

Conclusions The use of L-Betargin for a month in men with idiopathic pathospermia leads to an increase in the concentration of sperm and increase their motility, while normalizing all parameters of the spermogram.

Conclusions The use of L-Betargin for a month in men with idiopathic pathospermia leads to an increase in the concentration of sperm and increase their motility, while normalizing all parameters of the spermogram.

The aim of the present research was to investigate the rheological properties of the medicinal syrup for oral administration with glucosamine hydrochloride and levocarnitine.

Matherials and methods Coefficient of the dynamic flow (at shear rates of 3,49 and 10,3 s -1, as well as at shear rates of 27.2 and 149.0 s-1), mechanical stability, the index of destruction and restoration were studied. The rheological (structural-mechanical) properties of the samples were determined using a Rheolab QC rotary viscometer (AntonPaar, Austria) with coaxial cylinders CC27 / S-SN29766. The rheological parameters were studied at the temperature 20±0,5 °С.

Results It is established that the syrup has weakly expressed plastic viscous and thixotropic properties (the hysteresis area for the syrupis 1710.19 Pas/s). Such results characterize the system as a reopex.

Conclusions The results of the study enables classification of the research object as system with a low degree of fluidity. Such dependence is typical for systems of the Newtonian type of flow and characterizes the syrup under investigation as a weakly structured disperse system.

Conclusions The results of the study enables classification of the research object as system with a low degree of fluidity. Such dependence is typical for systems of the Newtonian type of flow and characterizes the syrup under investigation as a weakly structured disperse system.

The aim of this study was to determine the frequency of endodontic treatment in an adult Ukrainian population in relation to the age and its distribution depending on the type of the teeth.

Materials and methods A total of 435 digital panoramic radiographs of adults (aged 18 to 72 years) were examined. A tooth was qualified as root filled (endodontically treated), if radiopaque root-filling material was determined in the pulp chamber and/or in the root canals. Pearson's chi-squared test (χ2) and Spearman's rank correlation were applied for data analysis.

Results It was revealed that 82.5% of patients had previously received endodontic treatment of the teeth. The overall percentage of root filled teeth in adult dentition is 12.08%. The analysis of the rate of endodontically treated teeth in different age groups identified an increasing of treated teeth with age - from 5.2% in the youngest cohort (18-19 years old) to 24.9% in the oldest cohorts. It was revealed that 822 teeth (14.2%) on maxilla and 569 (9tment in comparison to other teeth groups.

Introduction Numerous risk factors for cardiovascular disease (CVD) are modifiable, therefore understanding their effects has a significant impact on lowering the incidence and mortality. The "Małopolska Cardiovascular Preventive Intervention Study (M-CARPI)" aims to educate the inhabitants of the voivodeship regarding preventative measures for developing CVD. The aim To examine the effectiveness of the seminars regarding preventative measures for developing CVD according to the M-CAPRI among the inhabitants of Lesser Poland.

Material and methods The seminars were carried out by a doctor with a specialization in cardiology, in the form of presentations, based on materials prepared by experts in accordance with European and Polish guidelines. Both initially and after the course, participants completed questionnaires regarding the subjects discussed.

Results The study covered 558 people (137 men, 411 women). The analysis was based on the sub-populations of retirees and non-retirees. The knowledge of risk ies to raise awareness of the importance of cardiological disease prevention. Preventive interventions are equally effective regardless of age or profession.

The aim To determine the dynamics of adaptation resources and the level of psychological safety of the personality in service members of the National Guard of Ukraine who participated in combat operations in the East of Ukraine.

Materials and methods To determine the peculiarities of military personnel adaptation to the combat activity, the "Adaptability-200" and "Disdaptability-45" methodologies were used. To determine the level of psychological safety of combatants we used "Diagnosis of psychological safety personality" and "Express diagnosis of psychological safety personality" Methodologies. TG100-115 supplier The study was carried out during 2017, with 163 military participating.

Results Being 2-3 weeks in combat conditions, 54% service members revealed high, 32% - average level of adaptability, and in 14% of them signs of non-adaptability were detected. The data of adaptation resources of combatants correlates with the results of diagnostics of psychological safety of personality in 43% of them high level, 42% - average and 15% - low level of psychological safety were revealed.

Conclusions The data obtained in the absolute majority of service members (86%) shows a good adaptability to combat conditions, and allows predicting adequate response to extreme conditions, high probability of preserving of the mental health and disability after the influence of vital factors.

Conclusions The data obtained in the absolute majority of service members (86%) shows a good adaptability to combat conditions, and allows predicting adequate response to extreme conditions, high probability of preserving of the mental health and disability after the influence of vital factors.

The aim of this study were to assess clinical (cutaneous allodynia) and neurophysiological (R2 nBR component) markers of the nociceptive trigeminal-cervical pathway sensitization in the abdominally obese patients with episodic (EM) and chronic migraine (CM).

Materials and methods It had been recorded nBR within interictal period in 79 migraineurs with EM and CM who had abdominal obesity (AO) and normal body weight (NBW).

Results Patients with EM and AO had significantly lower pain thresholds than patients with EM and NBW - 0,55 (0,34-0,63) μV vs 0,70 (0,59-1,03) μV. The mean latency of R2 nBR component was significantly decreased in patients who had EM and AO (36,59 (31,95-42,41) ms) compared to patients who had EM and NBW(46,75 (42,93-52,34) ms). It had been revealed significant increasing of the mean amplitude of the component R2 nBR in patients who had EM and AO (158 (115-197) μV) compared to patients who had EM and NBW (124 (76-144) μV). In patients who had CM and AO, it had been found direct positive correlation between the amplitude of R2 nBR and severity of cutaneous allodynia - τ=0,4 (p=0,03), as well as found negative correlation between the latency of R2 nBR and severity of cutaneous allodynia - τ=-0,44 (p=0,02) within the interictal period of migraine.