Thorsenhughes1879

The aim of the study was to analyze fecal volatile organic compounds in premature babies born with a weight of less than 1,500 grams in order to identify predictors of BPD. The study presents the results of the study in parallel groups, which are represented by premature babies born with a weight of less than 1500 grams. In the course of scientific work, 137 children were examined, from which stool samples were taken on the 14th and 28th days of life to detect VOCs using gas chromatography with mass spectrometry (GC/MS). The Torion T-9 GC / MS was used to separate and identify the VOCs present in the feces of the subjects. After sampling, these children were further divided into two groups group I (main) - children who realized BPD (n=89) and group II (control) - children who did not realize BPD (n=48). During the study, 28 VOCs were found in the feces of the subjects on the 14th and 28th days of life, among which the three most significant were identified, among them tetradecane, N-nitrosopyrrolidine, and trichloretene.The aim of the study is to assess the effectivity of the drug «Betargin» in complex management of patients with chronic hepatitis B (CHB) in remission of acute lymphoblastic leukemia (ALL). The research had shown the results of treatment of 41 children with CHB in remission of ALL aged from 3 to 17 years old, who were on dispensary observation in Vinnytsia Regional Children's Clinical Infectious Diseases Hospital during 2013-2017 years. Patients were devided into the following groups the comparison group (group A), which included 18 children with CHB in remission of ALL, who received basis therapy; the main group (group B) which consisted of 23 patients with CHB in remission of ALL, who got betaine arginine complex («Betargin») in addition to basis therapy. The control group was formed out of 30 healthy children. Determination of effectivity of the proposed treatment regimen was performed by studying the indicators of cholestasis, cytolysis, hepatocellular insufficiency, and lipid metabolism. To assess the linfirmed by a decrease in the level of plasma osteopontin up to 104,92 ng/ml against 178,15 ng/ml in the comparison group (p less then 0,05).Studies conducted in various departments of "Feofania" Clinical Hospital over the past 5 years, indicate the extremely widespread prevalence of arterial hypertension. According to a survey of a representative sample, the age-standardized prevalence of arterial hypertension in Feofania Clinical Hospital is 39.9% among men and 41.1% among women. Purpose of the study - to determine preventive measures for the prevalence of arterial hypertension among the cohort of medical workers of the "Feofania" Clinical Hospital. Among the complications of hypertension, the first places are occupied by lesions of the heart, blood vessels, kidneys, and brain. To reduce the number of patients with AH and its complicated forms, improve their quality of life, national measures are necessary to prevent risk factors (RF) for the development of this pathology. To date, three strategies are identified for preventive measures population-based, high-risk, and secondary prevention. 201 doctors participated, including 51 women (25.37%) ae a healthy lifestyle for the population. The prevalence of arterial hypertension and risk factors among medical workers is quite high, as in the unorganized population, while there is a low awareness of their disease and low treatment efficiency.Parenteral viral hepatitis is one of the most pressing medical and social problems, both in Ukraine and in the world, due to its high prevalence, the formation of chronic liver diseases, high risk of developing cirrhosis and hepatocellular carcinoma. The purpose of the study was to investigate the relationship between IL-4 (rs2243250), IL-10 (rs1800896) and TNFα (rs1800620), SMAD 7 (rs4939827) gene polymorphisms, and the degree of liver fibrosis to create a prognostic scale. A pilot study included 100 patients with chronic hepatitis C. Non-invasive Fibrotest, an alternative to puncture liver biopsy, was used to assess the degree of morphological changes. It has been suggested that the genotypes of СС IL-4 (rs2243250), GG TNFα (rs1800620), СС SMAD family member 7 (rs4939827) and have a protective effect on the course of chronic hepatitis C, as they are established in patients with HCV with less fibrosis. Homozygous genotypes of TT IL-4 (rs2243250), AA TNFα (rs1800620), TT SMAD family member 7 (rs4939827) have a pro-fibrotic effect on the course of chronic hepatitis C, as they are established in patients with high-fibrosis HCV. To create a prognostic scale, the projective and profibrotic genotypes of each individual patient were summarized. To simplify the summation, coding was performed each pro-fibrotic genotype was assigned a -1 point, each protective one a +1 mark, and then all genotype variants were summed together. The higher the score in a patient, the lower the likelihood of developing high-grade fibrosis. Comprehensive assessment of allelic gene polymorphism and degree of liver fibrosis allows to estimate with high degree of certainty the individual risk of disease progression, to predict the course of the disease in the early stages and to plan the tactics of patient management.Sedentary lifestyle leads to deteriorating health. This problem is especially on the rise in the era of computer technology development and increasing workplaces with inactive physical activities. Women in general are less physically active than men and more often suffer from obesity. Our goal was to study the correlation between body composition and indicators of the state of the cardiovascular system (CVS). Erdafitinib Women (42.5±5.4 years of age) of different body compositions were randomly selected. Body composition parameters were examined using Tanita BC-601 analyzer scales. CVS status was examined through endothelial function (EF) with the help of rheograph "ReoCom" (KHAI-Medica) and heart rate variability (HRV) using the electrocardiograph "CardioLab" (KHAI-Medica). The indicator of visceral fat (VF) was positively correlated with the degree of tension of regulatory systems (RS) and negatively with the indicator of endothelial function. The fat content in the extremities and torso was positively correlated with HRV, and the muscle content was negatively correlated with EF.