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To evaluate clinical and radiologic outcomes between bilateral decompression using the over-the-top technique (group 1) and unilateral decompression (group 2) in patients with claudication who underwent minimally invasive surgery transforaminal lumbar interbody fusion (MIS-TLIF).

We enrolled patients with claudication who underwent MIS-TLIF from January 2017 to June 2019. Visual analog scale (VAS) scores and Oswestry Disability Index (ODI), walking distance, and perioperative outcomes were compared between groups. Preoperative and 3-month postoperative magnetic resonance imaging assessed changes in canal cross-sectional area, foraminal height, and lateral recess area.

Sixty-five consecutive patients with ≥1 year of follow-up were enrolled. VAS scores and ODI were not significantly different between groups (VAS and ODI, respectively, at 1 month follow-up, P= 0.62 and 0.88; 3 months follow-up, P= 0.96 and 0.53; 6 months follow-up, P= 0.10 and 0.85; and 12 months follow-up, P= 0.10 and 0.66). Operative time and blood loss between groups was not statistically significant (P= 0.43 and P= 0.55). There was also no difference in the length of hospital stay (P= 0.24). Canal dimensions increased in each group without significant differences between groups (cross-sectional area, P= 0.92; foraminal height [approach and contralateral side, respectively], P= 0.62 and 0.66; and lateral recess area [approach and contralateral side, respectively], P= 0.68 and 0.50).

A unilateral approach with ipsilateral side direct decompression and contralateral indirect decompression in MIS-TLIF is sufficient for early clinical improvement in patients with claudication.

A unilateral approach with ipsilateral side direct decompression and contralateral indirect decompression in MIS-TLIF is sufficient for early clinical improvement in patients with claudication.

Microvascular decompression (MVD) for trigeminal neuralgia (TN) results in durable pain freedom in a large percentage of appropriately selected patients. The decision to perform MVD is based on a combination of clinical symptomatic presentation and imaging findings demonstrating neurovascular compression (NVC) with surgeons weighting these variables differently. This study sought to determine the relative importance of clinical symptomatic presentation and imaging findings of NVC in decision-making to pursue MVD for TN among North American board-certified neurosurgeons.

An online survey detailing the decision-making process involved in the workup and treatment of TN with MVD was distributed to all American Association of Neurological Surgeons registered board-certified neurosurgeons in North America.

From 3010 functional email addresses, there were 309 responses to the survey (10% response rate). AZD7545 manufacturer The majority of respondents (76%) reported only operating on patients with classic type 1 TN (T1TN) while only 32% chose to operate on patients with imaging findings of vascular compression in the absence of T1TN symptoms. In contrast to low-volume surgeons, high-volume surgeons weighed imaging evidence of vascular compression more heavily into the decision-making process to operate.

The majority of responding neurosurgeons weigh symptomatic presentation more heavily than imaging evidence of NVC when deciding on whom to perform MVD. High-volume surgeons tend to be more attentive to NVC in their decision-making to perform MVD when compared with low-volume surgeons.

The majority of responding neurosurgeons weigh symptomatic presentation more heavily than imaging evidence of NVC when deciding on whom to perform MVD. High-volume surgeons tend to be more attentive to NVC in their decision-making to perform MVD when compared with low-volume surgeons.

Anterior cervical discectomy and fusion (ACDF) can induce lordosis and improve cervical sagittal vertical axis (SVA), but multilevel ACDF may inadvertently increase cervical SVA because of insufficient lordosis induction.

Patients who underwent 1-, 2-, or ≥3-level ACDF in the subaxial spine with minimum 2-year follow up were retrospectively studied. C2-C7 Cobb angle (lordosis), cervical SVA, and T1 slope were measured preoperatively, immediately postoperatively, and at last follow-up.

Inclusion criteria were met by 127 patients. There were no differences in baseline demographics among 1-, 2-, and ≥3-level ACDF groups. Mean follow-up was 43.7 months (range, 24-142 months). Increase of cervical SVA immediately postoperatively was 1.94 mm,-1.44 mm, and 7.25 mm for 1-, 2-, and ≥3-level ACDF (P= 0.041) and at last follow-up was 2.97 mm, 0.70 mm, and 9.32 mm for 1-, 2-, and ≥3-level ACDF (P= 0.026). At last follow-up, 2-level ACDF patients had the greatest decrease in T1 slope (-0.43°) compared with increase vel ACDF, 2-level ACDF had the greatest ability to maintain lordosis. T1 slope had a significant correlation with loss of C2-C7 lordosis after ACDF.

Surgical treatment is widely used to treat patients with Hirayama disease (HD). However, postoperative follow-up with abundant samples is still scarce. This study investigated short-term to midterm clinical outcomes after anterior cervical discectomy and fusion (ACDF) among patients with HD.

We enrolled 115 patients with HD who had undergone ACDF. Radiographic parameters included cervical lordosis (CL), sagittal vertical axis, segment lordosis (SL), T1 slope (T1S), T1S minus CL, range of motion (ROM), upper/lower adjacent segment ROM, and upper adjacent SL. Electrophysiologic parameters included the maximal compound muscle action potentials (CMAPs) of abductor digit minimi and abductor pollicis brevis, the latency of the ulnar nerve F reaction, and abnormal spontaneous action potentials. link2 Clinical assessment included the selected brief-Michigan Hand Questionnaire and Odom scale.

The average age was 19.5 ± 4.5 years. The mean follow-up time was 16.35 ± 9.21 months. CL, SL, and T1S increased, whereas sagittal vertical axis and ROM decreased at the final follow-up (P < 0.001). Upper adjacent SL, upper adjacent ROM, and lower adjacent ROM were stable after ACDF (P > 0.05). The maximal CMAPs of abductor digit minimi and the latency of the ulnar nerve F reaction improved bilaterally (P < 0.05), whereas there was no significance in the maximal CMAPs of abductor pollicis brevis (P > 0.05). Abnormal spontaneous action potentials reduced remarkably. The selected brief-Michigan Hand Questionnaire score increased after surgery (P < 0.001). The Odom scale showed a ratio of 79.1% (excellent and good ratio).

This study showed favorable radiologic, electrophysiologic, and clinical outcomes after ACDF among patients with HD.

This study showed favorable radiologic, electrophysiologic, and clinical outcomes after ACDF among patients with HD.

Posterior vertebral column resection (PVCR) is a versatile technique for correction of severe and rigid spinal deformities, but the high rate of neurological complications is a major disadvantage of this procedure. This study aimed to describe a modified PVCR technique for safe treatment of severe post-tuberculous kyphotic deformity.

Four consecutive patients with severe post-tuberculous kyphosis underwent modified PVCRs. Radical removal of the posterior elements was avoided by performing laminectomy in stages, and the posterior vertebral wall and the bases of the spinous processes were maintained throughout the procedure. Perioperative clinical presentation, imaging data, and operative variables were recorded.

Desirable efficacy and clinical outcomes were obtained, including satisfactory correction rates and low estimated blood loss. Neurological status improved in all patients with preoperative neurological deficits, and no postoperative neurological complications were reported.

Modified PVCRs could prevent excessive handling or overstretching of the spinal cord, reduce bleeding, and provide more security in the correction of severe spinal deformities. Our initial experience showed that this modified procedure might be an alternative to conventional Schwab grade 6 osteotomy for the correction of severe post-tuberculous kyphotic deformity.

Modified PVCRs could prevent excessive handling or overstretching of the spinal cord, reduce bleeding, and provide more security in the correction of severe spinal deformities. Our initial experience showed that this modified procedure might be an alternative to conventional Schwab grade 6 osteotomy for the correction of severe post-tuberculous kyphotic deformity.Spontaneous spinal cerebrospinal fluid (CSF) leak is a condition that commonly presents with debilitating positional headaches. link3 Often, the cause of the leak is located in the spine. Although often cured with conservative management, including epidural blood patching, a subset of patients are refractory to this initial management. Determining the focal location of the spinal leak can, in some patients, require several imaging modalities. Treatment similarly involves multiple options, including targeted epidural blood and/or fibrin patching as well as surgical closure. In this article, we review the current literature regarding this challenging condition and present an algorithm for management.

The endoscopic endonasal approach (EEA) has been applied in the treatment of olfactory neuroblastoma (ONB). However, there is a lack of research examining the impact of EEA on locally advanced ONB. This study assessed the outcomes of EEA in patients with locally advanced ONB and its impact on the quality of life (QOL).

We retrospectively reviewed patients with Kadish stage C ONB who underwent EEA between December 2004 and October 2019 and assessed demographic data, histopathologic grade, the extent of resection, postoperative complications, and outcomes. Preoperative and postoperative QOL was assessed using the Sino-Nasal Outcome Test.

Twenty-six patients (18 men, 8 women; aged 26-79 years) were enrolled, with 12 cases of Hyams grade II and III and 1 case of grade I and IV each. In total, 25 patients received radiotherapy and 16 patients received chemotherapy, of whom 11 received preoperative neoadjuvant chemotherapy. Postoperative nasal bleeding was observed in 2 patients. The follow-up ranged from 8 to 124 months (median, 42.3 months). The 1-year and 5-year overall survival were 96.2% and 84.8%, respectively. The 1-year and 5-year disease-free survival were 76.9% each. The analysis of the postoperative Sino-Nasal Outcome Test scores showed significant improvement in certain psychological and sleep-associated domains, compared with the preoperative scores.

Our results showed that pure EEA followed by radiotherapy offered excellent outcomes in the management of selected patients with locally advanced ONB. The postoperative QOL was significantly improved. More research is required on neoadjuvant chemotherapy to establish its role.

Our results showed that pure EEA followed by radiotherapy offered excellent outcomes in the management of selected patients with locally advanced ONB. The postoperative QOL was significantly improved. More research is required on neoadjuvant chemotherapy to establish its role.Arachnoid web (AW) is a rare phenomenon that has only been described in small case reports and case series,1 most commonly presenting with upper motor neuron signs and subtle radiographic findings, such as the classically described "scalpel sign."2 In this report, we demonstrate the use of imaging and operative techniques that have not been previously shown in the literature as a video for AW. These include high-definition magnetic resonance imaging (MRI) sequences for preoperative diagnosis, use of intraoperative ultrasonography for identification of adhesions, and operative technique for AW fenestration (Video 1). The patient consented to this manuscript. A 64-year-old female patient developed progressive difficulty with balance and ambulation that particularly worsened over the last 4 months associated with tingling and numbness in the bilateral lower extremities. Physical examination revealed spastic gait and upper motor neuron signs in the lower extremities along with left foot drop. MRI revealed a chronic noncontrast-enhancing intramedullary lesion, along with a spinal cord indentation at the level T6 with an associated fiber between the cord and the posterior dura.

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