Mcdonoughwoodruff5500

Use of Electronic Nicotine Delivery Systems (ENDS, colloquially known as "electronic cigarettes") has increased substantially in the United States in the decade since 2010. However, currently relatively little is known regarding the documentation of ENDS use in clinical notes. With this study, we describe the development of an annotation scheme (and associated annotated corpus) consisting of 4,351 ENDS mentions derived from Department of Veterans Affairs clinical notes during the period 2010-2020. Analysis of our corpus provides important insights into ENDS documentation practices at the VA, in addition to providing a resource for the future development and validation of Natural Language Processing algorithms capable of reliably identifying ENDS-use status.Chest X-ray becomes one of the most common medical diagnoses due to its noninvasiveness. The number of chest X-ray images has skyrocketed, but reading chest X-rays still have been manually performed by radiologists, which creates huge burnouts and delays. Traditionally, radiomics, as a subfield of radiology that can extract a large number of quantitative features from medical images, demonstrates its potential to facilitate medical imaging diagnosis before the deep learning era. In this paper, we develop an end-to-end framework, ChexRadiNet, that can utilize the radiomics features to improve the abnormality classification performance. Specifically, ChexRadiNet first applies a light-weight but efficient triplet-attention mechanism to classify the chest X-rays and highlight the abnormal regions. Then it uses the generated class activation map to extract radiomic features, which further guides our model to learn more robust image features. After a number of iterations and with the help of radiomic features, our framework can converge to more accurate image regions. We evaluate the ChexRadiNet framework using three public datasets NIH ChestX-ray, CheXpert, and MIMIC-CXR. We find that ChexRadiNet outperforms the state-of-the-art on both disease detection (0.843 in AUC) and localization (0.679 in T(IoU) = 0.1). We make the code publicly available at https//github. com/bionlplab/lung_disease_detection_amia2021, with the hope that this method can facilitate the development of automatic systems with a higher-level understanding of the radiological world.Analysing electrocardiograms (ECGs) is an inexpensive and non-invasive, yet powerful way to diagnose heart disease. ECG studies using Machine Learning to automatically detect abnormal heartbeats so far depend on large, manually annotated datasets. While collecting vast amounts of unlabeled data can be straightforward, the point-by-point annotation of abnormal heartbeats is tedious and expensive. We explore the use of multiple weak supervision sources to learn diagnostic models of abnormal heartbeats via human designed heuristics, without using ground truth labels on individual data points. Our work is among the first to define weak supervision sources directly on time series data. Results show that with as few as six intuitive time series heuristics, we are able to infer high quality probabilistic label estimates for over 100,000 heartbeats with little human effort, and use the estimated labels to train competitive classifiers evaluated on held out test data.Documentation burden continues to be a critical issue in the adoption of comprehensive electronic health record systems. This case study demonstrates how the i-PARIHS framework can be applied to support the implementation of interventions in reducing documentation and EHR-related burden in a mental health context. As part of pre-adoption implementation activities for Speech Recognition Technology (SRT), a cross-sectional survey was conducted with physicians, residents, and fellows at an academic mental health hospital to explore their perceptions on SRT. Open-ended responses and follow-up interviews explored challenges and concerns on using SRT in practice. Through an analysis using the i-PARIHS framework, key considerations were mapped across the four components of the framework. This study demonstrates the value of applying well-established implementation frameworks, such as the i-PARIHS framework, in mitigating challenges related to documentation burden. Future studies should explore how implementation frameworks can be systematically embedded in addressing EHR-related burden.Objective To establish and validate mappings between primary care clinical terminologies (Read Version 2, Clinical Terms Version 3) and Phecodes. Methods We processed 123,662,421 primary care events from 230,096 UK Biobank (UKB) participants. Zeocin We assessed the validity of the primary care-derived Phecodes by conducting PheWAS analyses for seven pre-selected SNPs in the UKB and compared with estimates from BioVU. Results We mapped 92% of Read2 (n=10,834) and 91% of CTV3 (n=21,988) to 1,449 and 1,490 Phecodes. UKB PheWAS using Phecodes from primary care EHR and hospitalizations replicated all (n=22) previously-reported genotype-phenotype associations. When limiting Phecodes to primary care EHR, replication was 81% (n=18). Conclusion We introduced a first version of mappings from Read2/CTV3 to Phecodes. The reference list of diseases provided by Phecodes can be extended, enabling researchers to leverage primary care EHR for high-throughput discovery research.The development and adoption of Electronic Health Records (EHR) and health monitoring Internet of Things (IoT) Devices have enabled digitization of patient records and has also substantially transformed the healthcare delivery system in aspects such as remote patient monitoring, healthcare decision making, and medical research. However, data tends to be fragmented among health infrastructures, and prevents interoperability of medical data at the point of care. In order to address this gap, we introduce BlockIoT that uses blockchain technology to transfer previously inaccessible and centralized data from medical devices to EHR systems, which provides greater insight to providers who can, in turn, provide better outcomes for patients. This notion of interoperability of medical device data is possible through an Application Programming Interface (API), which serves as a versatile endpoint for all incoming medical device data, a distributed file system that ensures data resilience, and knowledge templates that analyze, identify, and represent medical device data to providers. Our participatory design survey on BlockIoT demonstrates that BlockIoT is a suitable system to supplement physicians' clinical practice and increases efficiency in most healthcare specialties, including cardiology, pulmonology, endocrinology, and primary care.Data sharing is necessary to address communication deficits along the transitions of care among community settings. Evidence-based practice supports home healthcare (HHC) patients to see their primary care team within the first two weeks of hospital discharge to reduce rehospitalization risk. A small subset of patient data collected at HHC admission is mandated to be transmitted to primary care, predominantly by fax. Using qualitative analysis, we assessed completeness of the United States Core Data for Interoperability (USCDI) interoperability standard, as compared to the patient data collected by the primary care team (topics) and HHC (classes) during the initial visit; and offer interoperability recommendations. Findings indicate the USCDI does not cover 74% of the 19 faxed HHC classes that mapped to the primary care topics, and 95% of the 38 not-faxed HHC classes. We offer USCDI recommendations to address these interoperability gaps.The adoption of best practices has been shown to increase performance in healthcare institutions and is consistently demanded by both patients, payers, and external overseers. Nevertheless, transferring practices between healthcare organizations is a challenging and underexplored task. In this paper, we take a step towards enabling the transfer of best practices by identifying the likely beneficial opportunities for such transfer. Specifically, we analyze the output of machine learning models trained at different organizations with the aims of (i) detecting the opportunity for the transfer of best practices, and (ii) providing a stop-gap solution while the actual transfer process takes place. We show the benefits ofthis methodology on a dataset ofmedical inpatient claims, demonstrating our abilityto identify practice gaps and to support the transfer processes that address these gaps.A wide range of datasets containing geographically distributed measures of the environment and social factors is currently available, and as low-cost sensors and other devices become increasingly used, the volume of these data will continue to grow. Because such factors influence many health outcomes, researchers with varied interests often repeat tasks related to gathering and preparing these data for studies. We created Sensor-based Analysis of Pollution in the Philadelphia Region with Information on Neighborhoods and the Environment (SAPPHIRINE), offered as a web application and R package, to integrate pollution, crime, social disadvantage, and traffic data relevant to investigators, citizen scientists, and policy makers in the Greater Philadelphia Area. SAPPHIRINE's capabilities include providing interactive maps and customizable data retrieval to aid in the visual identification of pollution and other factor hotspots, as well as hypothesis generation regarding relationships among these factors and health outcomes.The use of copy-paste in authoring clinical notes has been widely embraced by busy providers, but inappropriate copy-paste has been lambasted by critics for introducing risks related to patient safety and regulatory compliance. At an integrated academic health system with over 4,100 providers writing notes, we developed a pragmatic approach to assess the use of copy-paste. From January 1-December 31, 2020, approximately 2.3M inpatient notes and 6.6M ambulatory clinic notes were authored in our electronic health record. Of the inpatient notes, 42% used copy-paste, and 19% of overall note content was copied; in ambulatory notes, 18% used copy-paste and 12% of note content was copied. We describe an approach for including providers' copy-paste usage statistics into the ongoing professional practice evaluation process required for hospital accreditation, thereby offering individual training opportunities related to the lack of use of copy-paste or its potential overuse.The rapidly changing situation characterized by the COVID-19 pandemic highlighted a need for new epidemic modeling strategies. Due to an absence of computationally efficient models robust to paucity of reliable data, we developed NetworkSIR, a model capable of making predictions when only the approximate population density is known. We then extend NetworkSIR to capture the effect of indirect disease spread on the progression of an epidemic (EnvironmentalSIR).A comprehensive, mapped social determinants of health (SDH) taxonomy in machine readable format was developed. The framework is intended to facilitate the extraction of social risk factors (SRFs) out of electronic health record (EHR) data and categorize them by domain and determinant to facilitate interpretation. Where other SDH frameworks have been focused on data input, this framework is designed from a data extraction point of view using EHR data in conjunction with published literature, public health policy documents, and official crosswalk maps. Frameworks developed by leading public health organizations were reviewed and synthesized to create an SDH framework comprising of 97 distinct SRFs organized under 16 domains. 2,329 medical codes across three standardized medical vocabularies, 10,896 free-text diagnosis descriptors, and 25 health insurance keywords were mapped to individual SRFs in the SDH framework. The framework is available as an open-source resource in Python dictionary or JSON format.