Enniswilhelmsen3049

Female infertility is a multifactorial condition constituting a worldwide public health problem. The ability to reproduce is an important product of any marriage, hence infertility may exert a negative impact on physical, financial, social and emotional wellbeing of affected couples. The cornerstone to the management of any disease, including infertility, is prevention. Identifying the modifiable risk factors of female infertility will aid at prevention, early detection, and treatment of medical conditions that can threaten fertility as well as promoting healthy behaviours that can preserve it.

To explore the risk profile of infertility among Qatari women and compare risk factors distribution among primary vs. secondary infertility.

A hospital-based case control study was conducted from September 17th, 2017- February 10th, 2018. Cases (

 = 136) were enrolled from infertility clinic and controls (pregnant women,

 = 272), were enrolled from antenatal clinic, Women Hospital, Hamad Medical Corporation (Hh early referral to secondary care if required.

This study highlighted the opportunities to strengthen public health as well as hospital-based health promotion programs importantly toward behavioural-related risk factors (e.g. smoking, obesity, STIs etc.). Selleck Tofacitinib Moreover, detecting, preventing, and managing modifiable risk factors through awareness, screening and early management of chronic diseases, may contribute at reduction of incidence and severity of infertility. Such interventions can be delivered at premarital, family planning, post-natal and antenatal clinics at primary health care with early referral to secondary care if required.[This corrects the article DOI 10.1186/s40734-020-0083-0.].The current research examined the link between both normal and malevolent personality, proactive attitude, and self-perceived employability across some highly investigated (Belgium, Switzerland) and under-investigated populations of sub-Saharan Africa (e.g., Togo), considering proactive attitude as a potential mediator and self-perceived employability as an outcome. Conducting such a study in contexts which present notable differences in political organization and linguistic diversity, might contribute to enriching the literature on the relationships between personality and self-perceived employability. A sample of 968 participants aged 18 to 85 including 335 Belgians (50% women), 279 Swiss (58.1% women) and 354 Togolese (43.5% women) completed a French version of the Zuckerman-Kuhlman-Aluja Personality Questionnaire (ZKA-PQ/SF), Short Dark Triad (SD3), Proactive Attitude Scale (PAS), and Perceived Employability Scale (PES). All four instruments exhibited metric invariance but did not systematically show scalar invariance across the three countries. ZKA-PQ/SF's activity and neuroticism and SD3's narcissism dimensions predicted perceived employability, and these relations were fully or partially mediated by proactive attitude in all cultural contexts. Moreover, perceived employability was predicted by aggressiveness and psychopathy in the Swiss sample and by sensation seeking in both the Swiss and the Belgian samples. Finally, proactive attitude fully mediated between sensation seeking and employability in Belgium and partially between psychopathy and employability in Switzerland. This study illustrates that the link between personality and employability may be mediated by proactive attitude and that these links may be quite robust across cultures.[This corrects the article DOI 10.1098/rsos.200327.].[This corrects the article DOI 10.1098/rsos.181085.].The COVID-19 epidemic can probably be ended and normal life restored, perhaps quite quickly, by weekly SARS-CoV-2 RNA testing together with household quarantine and systematic contact tracing. Isolated outbreaks could then be contained by contact tracing, supplemented if necessary by temporary local reintroduction of population testing or lockdown. Leading public health experts have recommended that this should be tried in a demonstration project in which a medium-sized city introduces weekly testing and lifts lockdown completely. The idea was not considered by the groups whose predictions have guided UK policy, so we have examined the statistical case for such a study. The combination of regular testing with strict household quarantine, which was not analysed in their models, has remarkable power to reduce transmission to the community from other household members as well as providing earlier diagnosis and facilitating rapid contact tracing.[This corrects the article DOI 10.1098/rsos.200007.].[This corrects the article DOI 10.1098/rsos.191848.].Obstructed by hurdles in information extraction, handling and processing, computer-assisted sperm analysis systems have typically not considered in detail the complex flagellar waveforms of spermatozoa, despite their defining role in cell motility. Recent developments in imaging techniques and data processing have produced significantly improved methods of waveform digitization. Here, we use these improvements to demonstrate that near-complete flagellar capture is realizable on the scale of hundreds of cells, and, further, that meaningful statistical comparisons of flagellar waveforms may be readily performed with widely available tools. Representing the advent of high-fidelity computer-assisted beat-pattern analysis, we show how such a statistical approach can distinguish between samples using complex flagellar beating patterns rather than crude summary statistics. Dimensionality-reduction techniques applied to entire samples also reveal qualitatively distinct components of the beat, and a novel data-driven methodology for the generation of representative synthetic waveform data is proposed.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; initially named as 2019-nCoV) is responsible for the recent COVID-19 pandemic and polymerase chain reaction (PCR) is the current standard method for its diagnosis from patient samples. This study conducted a reassessment of published diagnostic PCR assays, including those recommended by the World Health Organization (WHO), through the evaluation of mismatches with publicly available viral sequences. An exhaustive evaluation of the sequence variability within the primer/probe target regions of the viral genome was performed using more than 17 000 viral sequences from around the world. The analysis showed the presence of mutations/mismatches in primer/probe binding regions of 7 assays out of 27 assays studied. A comprehensive bioinformatics approach for in silico inclusivity evaluation of PCR diagnostic assays of SARS-CoV-2 was validated using freely available software programs that can be applied to any diagnostic assay of choice. These findings provide potentially important information for clinicians, laboratory professionals and policy-makers.