Nieveshinton4116

The deep insight into the chelation mechanism was visually presented via the orbital interaction diagram. In addition, the regeneration of the spent adsorbent, adsorption column test, and acute toxicity analysis demonstrated that the synthesized material has immense potential in terms of practical usage for the treatment of toxic pollutants. These results provide a novel path for researchers to properly understand the adsorption behavior.Objective. Evaluate compliance with the maximum permissible limits for pesticide residues in food in the state of Veracruz, as well as the risk to human health due to its consumption. Materials and methods. The concentration of pesticide residues in plant products were measured for comparison with the values established as safety limits and the regulatory framework for the use of pesticides. The hazard quotient and its possible effect on health were calculated. Results. 14.8% of the samples exceeded the allowed concentration. We found banned pesticides (methamidophos, monochotophos, triazophos and chlorpyrifos) that exceeded the established references dose, which increase the risk of possible neurological, hepatotoxic and endocrine alterations in health. Conclusions. There is the presence of highly hazardous pesticides, which are prohibited by international environmental conventions due to their impact on health and the environment, which is why their elimination is necessary. The regulatory framework in Mexico must be updated and dynamic as the knowledge of the adverse health effects of pesticides advances.Objective. Estimate the prevalence of generalized anxiety disorder (GAD) from April to June 2020. Materials and methods. Repeated cross-sections design based in the Encovid-19, a series of monthly mobile surveys with representative samples of Mexico (N= 833-1 674). The questionnaire includes the GAD-2 scale, and, in July, the GAD-7 scale was added; we examined its internal validity with confirmatory factor analysis and its concurrent validity with sociodemographic variables. Using GAD-7 as criterion, we analyzed the predictive validity of the GAD-2. We estimated the monthly prevalence with the GAD-2. Results. The GAD-7 and the GAD-2 are reliable and valid. The GAD-2 has a sensitivity of 0.87 and a specificity of 0.90. SapogeninsGlycosides The monthly prevalence remains high and stable, between 30.7 and 32.6%. GAD concentrated in women, unemployed and persons with low socioeconomic status. Conclusions. GAD is a public health problem that worsened during the Covid-19 pandemic.Objective. To analyze the relationship between chronic exposures to air pollution with Covid-19 death rate in Mexican cities. Materials and methods. Ecological study in 25 Mexican cities using the report of daily Covid-19 deaths (from February to June 2020) and validated data of air pollutants, considering average concentrations in each city for the last year. Poisson regression models using generalized additive models with adjustment variables (GAM) were used. Results. A significant increase of 3.5% (95% CI 2.3-4.7) was found in Covid-19 death rate for each 1μg/m3 in annual concentration of NO2. The association with PM2.5 was not significant, with an increase of 1.8% for each 1μg/m3. Conclusions. Results suggest an association between Covid-19 mortality and chronic exposure to NO2. This first approximation of the risk associated with air pollution requires a more precise analysis, but is consistent with what was observed in other studies.Sebaceous carcinoma is an uncommon primary cutaneous neoplasm which may be associated with mismatch repair (MMR) abnormalities and sometimes with Muir-Torre syndrome. These neoplasms rarely arise in the ovary within a teratoma/ dermoid cyst. We report a sebaceous carcinoma arising in an ovarian teratoma in a 49-yr old (the 14th case reported in the literature) which exhibited loss of expression of MMR proteins MSH2 and MSH6. A germline mutation c.1102C>T was present in exon 7 of the MSH2 gene, the first report of a germline mutation associated with this tumor type. In reporting this case, we review prior reports of primary ovarian sebaceous carcinoma. We recommend that all sebaceous carcinomas of the ovary undergo immunohistochemistry for MMR proteins for investigation of possible Lynch syndrome.A 56-year-old patient with a 1-year history of stable maintenance treatment with Suboxone for opioid use disorder (OUD) was switched to a generic formulation in May of 2019. The patient reported experiencing-over the course of the following 3 months-withdrawal symptoms when switched to the Alvogen-produced generic formulation in May of 2019 and then to the Sandoz-produced version in July of that same year, she also was positive for fentanyl during that time. As a result, the buprenorphine dose was increased, and the patient was stable at this new dose using the generic versions. Blood levels pre- and post-change (not reported in previous case reports) showed maximum buprenorphine concentration being reached more quickly when the brand-name drug was used. Additionally, the area under the curve (AUC) values indicate that the generic formulation had higher exposures than the brand-name drug. Based on the clinical impact of the brand-to generic switch in this patient, further research in this area is warranted. In the meantime, clinicians should carefully monitor their patients so that, if warranted, dose adjustments can be made quickly and safely to minimize negatively impacting the OUD therapy outcomes of patients.

To assess the impact of tinnitus in fibromyalgia.

A quantitative controlled study was carried out. The 25-item Tinnitus Handicap Inventory (THI) and the Revised Fibromyalgia Impact Questionnaire (FIQR) were administered to 27 patients who fulfilled the revised diagnostic criteria for fibromyalgia of the American College of Rheumatology and to 26 healthy controls who had no history of suffering from fibromyalgia or any other rheumatological or neurological illness.

The two groups were matched for age, sex and ethnicity. The fibromyalgia patients were significantly more likely to suffer from tinnitus than the controls 16 (59.3%) of the patients suffered from tinnitus, compared with two (7.7%) of the controls (p < 0.001). The median (interquartile range) total THI score for the fibromyalgia group was 6 (44), which was significantly higher than that of 0 (0) for the control group (p < 0.001). The fibromyalgia group scored significantly higher than the control group for 24 of the 25 THI items. The total THI score across all subjects was positively correlated with the FIQR scores (rs = 0.408, p = 0.002).

Fibromyalgia is associated with a relatively high prevalence of tinnitus.

Fibromyalgia is associated with a relatively high prevalence of tinnitus.

To assess COVID-19 vaccine providers' adherence to best practices and identify knowledge and practice gaps to guide corrective actions and retraining activities in Puerto Rico.

A CDC supportive evaluation tool was modified to collect information on vaccine storage, handling, preparation, administration, and post-vaccination care. Assessment visits to COVID-19 vaccine providers in Puerto Rico were conducted a month after the availability of COVID-19 vaccines in the island.

A total 16 vaccine providers were visited, 12 (75%) administering Pfizer-BioNTech vaccine and 4 (25%) administering Moderna vaccine. All providers adhered to correct handling practices after vaccine thawing. Required resources for managing anaphylaxis on site were available in all sites. Few instances of incorrect use of retractable-needle syringes, unapproved temperature monitoring devices, and lack of recorded temperature data were observed. Corrective actions were taken during the evaluation visit.

No major deficiencies that could jeopardize vaccine viability or patient safety were found. The use of a supportive evaluation tool during assessment visits is helpful to determine needs for vaccine providers retraining and to continue the safe administration of COVID-19 vaccines in Puerto Rico.

No major deficiencies that could jeopardize vaccine viability or patient safety were found. The use of a supportive evaluation tool during assessment visits is helpful to determine needs for vaccine providers retraining and to continue the safe administration of COVID-19 vaccines in Puerto Rico.

To investigate the relationship between optic nerve sheath diameter (ONSD) and clinical and carboxyhemoglobin levels in patients with carbon monoxide poisoning.

This prospective cross-sectional study enrolled 55 consecutive adult patients with carbon monoxide poisoning. The demographic and clinical characteristics of the patients and the diameters of the optic nerve sheaths of both eyes of those patients at the time of admission and at the 6th hour after receiving 100% oxygen therapy and/or hyperbaric oxygen therapy were determined. The ages, genders, arterial blood pressure values, symptoms, carboxyhemoglobin levels, and bilateral ONSD values (measured sonographically before and after the oxygen therapy) of the patients were recorded in a data collection form.

Measurements of ONSD before and after treatment were observed significantly (P = .01). Significant decreases were observed in ONSDs after treatment (P < .05). However, no significant difference was observed between ONSDs at the time of admission and after the treatment of patients receiving 2-hour single-session hyperbaric oxygen therapy and 100% oxygen therapy with a reservoir mask (P > .05).

The changing of ONSD, which is an indirect indicator of increased intracranial pressure, is a promising method to use at emergency service for patients with carbon monoxide poisoning.

The changing of ONSD, which is an indirect indicator of increased intracranial pressure, is a promising method to use at emergency service for patients with carbon monoxide poisoning.

Strongyloidiasis is a parasitic infection classified by the World Health Organization as a neglected tropical disease. Although predominantly asymptomatic, it can become a life-threatening disease in an immunocompromised host. Epidemiologic studies in the Western Hemisphere are scarce, but even more scarce are descriptions of the natural course of this disease. Our objectives were to identify the different manifestations and outcomes of Strongyloides stercoralis infection in the Hispanic veteran population in Puerto Rico. We also discuss the importance of pursuing a timely diagnosis in high-risk patients migrating from or traveling to endemic areas, regardless of their symptomatic status.

This was a single-center, retrospective record review study involving patients diagnosed with S. stercoralis via serology, stool samples, or organ biopsies, from 2008 through 2014.

A total of 270 patients tested positive; 210 (77.8%) were asymptomatic. The mean age at diagnosis was 75.4 years old. Symptomatic patients prevent potentially fatal outcomes, especially when considering immunosuppressive drugs.

To describe the clinical features, upon initial presentation, of a cohort of patients with Vogt-Koyanagi-Harada (VKH) disease who live in Puerto Rico.

A retrospective medical record review of patients with VKH was performed. The demographic and clinical characteristics were analyzed.

Twenty-two patients who met the diagnostic criteria for VKH were identified and included in the analysis. The median age at presentation was 41 years; 68.2% were female, and all patients were Hispanics. Bilateral disease was present in 90.9% of patients, and 59.1% of patients were categorized as having probable VKH. A headache was reported in 54.5% of patients and was the most common complaint at the time of presentation; the second most common complaint was tinnitus, which was present in 22.7% of patients. Vitiligo, alopecia, and meningismus were each preset in 9.1% of patients while hearing loss and aseptic meningitis were each reported in 4.5% of patients. Seventy-seven percent of patients had either topical or systemic corticosteroid use prior to the initial encounter.