Curtistodd4290

To describe a case of endogenous endophthalmitis (EE) following severe COVID-19 disease, review patient outcomes with EE following COVID-19 infection, review evidence regarding risk factors for developing EE.

Review of health records, imaging, intravitreal injection, and pars plana vitrectomy for bilateral fungal EE following severe COVID-19 disease. Literature review on outcomes in EE following COVID-19 disease.

63 year-old male with diabetes and hypertension was admitted to hospital for severe COVID-19 disease for 3 months. His stay required ICU admission, intubation, high-dose corticosteroids, tocilizumab, and was complicated by bacteremia, empyema, and fungal esophagitis. He developed floaters and bilateral vision loss (visual acuity 20/40 OD, CF OS) with vitritis 2.5 months into his stay that did not respond to intravitreal voriconazole. click here Pars plana vitrectomy was performed for both eyes, resulting in visual acuity of 20/40 OD, 20/30 OS. Vitreous cultures were positive for candida albicans. EE following COVID-19 disease has been reported in 22 patients to date, and outcomes are poor, with 40%+ of eyes legally blind (20/200 or worse). Although influenced by availability of imaging modalities and degree of training of the evaluating physician, misdiagnosis can affect ¼ of cases, delaying treatment. Age, male gender, and diabetes increase risk of severe COVID-19, which requires prolonged hospitalization, invasive catheretization, and immunosuppression, which in turn increases risk of nosocomial infection.

Low threshold for suspecting endogenous endophthalmitis in patients presenting with floaters and decreased vision following severe COVID-19 disease is necessary to ensure prompt recognition and treatment.

Low threshold for suspecting endogenous endophthalmitis in patients presenting with floaters and decreased vision following severe COVID-19 disease is necessary to ensure prompt recognition and treatment.Due to its goal-orientation, rehabilitation may be considered a future-oriented practice. As rehabilitation is increasingly recognized as contributing to dementia care it is important to explore how rehabilitation corresponds with the future orientation of older people with dementia.The aim of this study was to explore the futurework of home-dwelling people with mild to moderate dementia in the context of rehabilitation-focused municipal dementia care, that is, their thinking and practices regarding their future and how these correspond with institutionalized practices.The study was conducted as a case-study inspired by the methodology of Institutional Ethnography (IE). The study setting was two Danish municipalities sampled as a paradigmatic case. Eight older people living with early-stage dementia (mean age 78 years, age range 65-91) were strategically sampled and each interviewed recurringly within a period of six through 15 months. In total, 29 interviews were completed. An abductive analysis was subsequently conducted based on these interviews.Findings included three dimensions of futurework Extending the present state into the near future; avoiding being confronted with an anticipated future; and adjusting to decline and preparing for future losses. Based on these findings, a notion of 'ambivalent futurework' is suggested. The futurework of older people did not always correspond with the institutional arrangements in a rehabilitation-focused dementia care. Findings show that the institutional arrangements in dementia care may support as well as challenge the futurework of the participants. Paying attention to the ambivalences of older people living with dementia and recognizing the ambivalent futurework may be essential in rehabilitation-focused dementia care.Slippery liquid-infused porous surfaces (SLIPS) are an innovation that reduces droplet-solid contact line pinning and interfacial friction. Recently, it has been shown that a liquid analogue of Young's law can be deduced for the apparent contact angle of a sessile droplet on SLIPS despite there never being contact by the droplet with the underlying solid. Since contact angles on solids are used to characterize solid-liquid interfacial interactions and the wetting of a solid by a liquid, it is our hypothesis that liquid-liquid interactions and the wetting of a liquid surface by a liquid can be characterized by apparent contact angles on SLIPS. Here, we first present a theory for deducing liquid-liquid interfacial tensions from apparent contact angles. This theory is valid irrespective of whether or not a film of the infusing liquid cloaks the droplet-vapor interface. We show experimentally that liquid-liquid interfacial tensions deduced from apparent contact angles of droplets on SLIPS are in excellent agreement with values from the traditional pendant drop technique. We then consider whether the Zisman method for characterizing the wettability of a solid surface can be applied to liquid surfaces created using SLIPS. We report apparent contact angles for a homologous series of alkanes on Krytox-infused SLIPS and for water-IPA mixtures on both the Krytox-infused SLIPS and a silicone oil-infused SLIPS. The alkanes on the Krytox-infused SLIPS follow a linear relationship in the liquid form of the Zisman plot provided that the effective droplet-vapor interfacial tension is used. All three systems follow a linear relationship on a modified Zisman plot. We interpret these results using the concept of the critical surface tension (CST) for the wettability of a solid surface introduced by Zisman. In our liquid surface case, the obtained critical surface tensions were found to be lower than the infusing liquid-vapor surface tensions.Mesenteric artery dissection (D) and wall-thickening (WT) are rare vasculopathies that can lead to serious complications. This is a single center analysis of all patients evaluated for mesenteric arterial (celiac, superior (SMA) and/or inferior mesenteric (IMA)) D and/or WT from January 1, 2000, to January 31, 2020 at our hospital. Among the 101 included patients, the average age was 55.6 ± 13.6 years, mostly affecting men (62%). There were 20 celiac artery D, 8 WT, 15 D with WT, 15 SMA D, 7 WT, 8 D with WT, one IMA D, two WT, and 25 with multiple arterial involvement. Primary etiologies included segmental arterial mediolysis (SAM) (n = 17), isolated D (n = 17), localized vasculitis of the gastrointestinal tract (LVGT) (n = 16), fibromuscular dysplasia (FMD) (n = 13), extension of thoracoabdominal aortic D (n = 12), and trauma (n = 12). Most (71%) patients presented with abdominal pain. Hypertension (55%), hyperlipidemia (33%) and tobacco use (31%) were prevalent. Management included conservative (22%), medical (47%), endovascular (19%), and/or open repair (12%) with high in-hospital survival (98%) and symptom relief (73%). Our paper complements the scarce literature addressing the diagnosis and management of rare mesenteric vasculopathies. Most patients improved with conservative management, reserving endovascular or surgical interventions for symptomatic patients with more complicated presentations.

First aid training is a cost-effective way to improve public health, but the most effective methods to teach first aid are currently unclear. The aim of this research was to investigate the added value of simulated patients during first aid certification trainings.

Occupational first aid trainings organized by the Belgian Red Cross between September 2018 and August 2019 were allocated to either training with a simulated patient or regular training, for the topics "stroke" and "burns." Participants' knowledge and self-efficacy related to these topics were assessed at baseline, directly after training and after 1 year. First aid skills for "stroke" and "burns" and participant satisfaction were assessed after training. Knowledge and self-efficacy were measured via a questionnaire, and skills were assessed during a practical skills test. Data were analyzed using generalized linear mixed model analyses.

A total of 1113 participants were enrolled, 403 in the simulated patient group and 710 in the control group. First aid knowledge and self-efficacy increased strongly immediately after training. These increases did not differ between groups, nor did the level of practical skills. The simulated patient group had a significantly increased retention in first aid knowledge after 1 year, compared with control, while retention in self-efficacy did not differ. Participant satisfaction with training was similar between groups.

Using simulated patients during occupational first aid trainings for laypeople did not improve outcomes immediately after training but did improve retention of first aid knowledge after 1 year. These results support the use of simulated patients during first aid training.

Using simulated patients during occupational first aid trainings for laypeople did not improve outcomes immediately after training but did improve retention of first aid knowledge after 1 year. These results support the use of simulated patients during first aid training.

We report a novel method of intra-operative localization of a retained anterior intraocular foreign body (IOFB), using a combination of ultrasound biomicrosopy (UBM) and an insulated needle.

A retrospective case report of 56-year-old male who presented with a right eye IOFB.

On presentation, vision was decreased in the right eye to count fingers with a small subconjunctival hemorrhage but no other signs of a penetrating laceration. Orbital CT revealed an IOFB and the initial vitrectomy failed to retrieve the IOFB. Then during the subsequent vitrectomy, using an ultrasound compatible needle and a UBM, we were able to precisely locate and remove the small anterior IOFB.

Retained IOFBs can lead to severe irreversible vision loss if not promptly removed. Ancillary imaging modalities and localization techniques can help locate occult IOFBs in difficult cases.

Retained IOFBs can lead to severe irreversible vision loss if not promptly removed. Ancillary imaging modalities and localization techniques can help locate occult IOFBs in difficult cases.Unique structure and ability to control the surface termination groups of MXenes make these materials extremely promising for solid lubrication applications. Due to the challenging delamination process, the tribological properties of two-dimensional MXenes particles have been mostly investigated as additive components in the solvents working in the macrosystem, while the understanding of the nanotribological properties of mono- and few-layer MXenes is still limited. Here, we investigate the nanotribological properties of mono- and double-layer Ti3C2Tx MXenes deposited by the Langmuir-Schaefer technique on SiO2/Si substrates. The friction of all of the samples demonstrated superior lubrication properties with respect to SiO2 substrate, while the friction force of the monolayers was found to be slightly higher compared to double- and three-layer flakes, which demonstrated similar friction. The coefficient of friction was estimated to be 0.087 ± 0.002 and 0.082 ± 0.003 for mono- and double-layer flakes, respectively. The viscous regime was suggested as the dominant friction mechanism at high scanning velocities, while the meniscus forces affected by contamination of the MXenes surface were proposed to control the friction at low sliding velocities.