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Periodontal infections are an important risk factor for systemic disease and are driven primarily by the cytokines. Migration Inhibitory Factor (MIF) is a key cytokine which mediates acute and chronic inflammation alongside, a molecular link between chronic inflammation and immune mediated conditions. Hence, the present study was carried to measure the serum MIF levels in periodontal health, disease and to correlate the levels with the clinical parameters.

Sixty subjects were divided into three groups (each group n = 20) based on the gingival index (GI), probing pocket depth (PPD), and clinical attachment level (CAL) as group I healthy; group II gingivitis; and group III chronic periodontitis. The serum MIF level was measured using quantitative sandwich enzyme immunoassay technique.

Highest level was detected in Group III with a mean of 71.8 ng/ml and the lowest in group I (6.1 ng/ml). Serum MIF levels did not correlate with the clinical parameters.

Increased serum MIF levels in chronic periodontitis patients suggest its role as an inflammatory biomarker and may have a role in inflating the systemic inflammation. Summary Serum Migration inhibitory factor can be used as an inflammatory marker for periodontal disease.

Increased serum MIF levels in chronic periodontitis patients suggest its role as an inflammatory biomarker and may have a role in inflating the systemic inflammation. Summary Serum Migration inhibitory factor can be used as an inflammatory marker for periodontal disease.

To evaluate the association of oral health literacy (OHL) with oral health behavior and oral health outcomes among dental patients in Hyderabad City.

Cross-sectional study among dental patients.

A convenience sample of 605 adults >18 years of age visiting the out-patient Department of Public Health Dentistry of Government Dental College and Hospital, Hyderabad, were recruited. The five-item scale developed by Ishikawa was used to measure communication and critical OHL. Socioeconomic status was assessed using Modified Kuppuswamy's scale and questions for oral health behavior included frequency of toothbrushing, frequency of dental visit, and reason for visit. Dentition status, periodontal status, and loss of attachment were recorded according to World Health Organisation Survey methods.

Frequency distribution was done and association between the variables and predictors (oral health behavior and oral health status) of OHL was calculated using odds ratio.

The mean age of the study population was 31.5 + 11.2 years. selleck compound None of the individuals' questions of OHL questionnaire had 50% response of strongly agree or agree. The oral health parameters of decayed and filled teeth emerged as a significant predictor for model 1 (adjusted by sex and age) and model 2 (adjusted by sex, age, and social class). Likewise, toothbrushing frequency was significantly associated with low OHL.

This study shows a high prevalence of low OHL in the study population, with decayed teeth and filled teeth and oral health behavior like toothbrushing only once as a significant predictor for low OHL.

This study shows a high prevalence of low OHL in the study population, with decayed teeth and filled teeth and oral health behavior like toothbrushing only once as a significant predictor for low OHL.

The present study was conducted to assess the clinical efficacy (against plaque and gingivitis) and antimicrobial efficacy (against gram negative, gram positive and S. mutans counts) of T. cordifolia (Guduchi).

A nonrandomized before and after trial for 21 days of intervention was performed involving 17 participants. Plaque index, gingival index were recorded and saliva samples were collected at baseline, 13

day and 22

day. Repeated measures ANOVA test was performed to compare the before and after results of the clinical parameters, i.e. score of plaque index and gingival index. Freidman's test was applied for comparison between the three intervals (for microbiological evaluation of colony counts).

There was statistically significant reduction inplaque score, gingival score, and colony forming units of gram negative organisms and S. mutans from baseline to 22

day (P = 0.001). There was no significant reduction with gram positive organisms.

This clinico-microbiological study concluded that twice rinsing of T.cordifolia decoction as mouth rinse in adjunct to scaling and routine brushing of teeth for 21 days shows anti-plaque, anti-gingivitis, and antimicrobial action against gram negative organisms and S. mutans.

This clinico-microbiological study concluded that twice rinsing of T.cordifolia decoction as mouth rinse in adjunct to scaling and routine brushing of teeth for 21 days shows anti-plaque, anti-gingivitis, and antimicrobial action against gram negative organisms and S. mutans.Cardiopulmonary resuscitation (CPR) is widely practised by healthcare professionals to revive heart beat and breathing in a patient suffering from cardiac/respiratory arrest. It is increasingly being recognized that in some patients with specific medical conditions, CPR does not alter the overall outcome of illness, and is likely to increase suffering and further deteriorate the quality of life. Do not attempt resuscitation (DNAR) as an option has been practised in many countries for such cases to avoid futile CPR and maintain dignity of the patient. The decision of DNAR should be taken by the treating physician who is well versed with the patient's medical condition, with information to the patient or her/his surrogate. While ordering DNAR on the patient's medical case record, every effort should be made to treat the underlying disease and continue optimal medical care with compassion. This policy document describes the principles for DNAR, offers an algorithm and format for its implementation, and guidance on frequently asked questions.

. Undergraduate research experience has become increasingly relevant for today's medical students, considering the professional requirements of their challenging future.

. In the mentored student project (MSP) programme at Melaka Manipal Medical College, students undertake a short-term group research project under the guidance of their mentor. After data collection and analysis, students are required to write an abstract, present a poster and also write individual reflective summaries of their research experience. We evaluated the MSP programme using reflective summaries of a batch of undergraduate medical students. Data from 41 reflective summaries were analysed using the thematic analysis approach. The learning outcomes at the third and fourth levels of the Kirkpatrick evaluation model were determined from the summaries.

. Students' reflective summaries indicated that they were satisfied with the MSP experience. In all the summaries, there was a mention of an improvement in teamwork skills through MSP.

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