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74, 95%CI 1.33, 2.26; and long vs optimal, adjusted OR = 1.51, 95%CI 1.18, 1.93). When stratified by weight status, the participants with central obesity showed highest prevalence of asthma among the three sleep duration groups. With the adjustment of confounding factors, underweight and obesity grouped by waist to height ratio and conicity index remained associated with higher risk of asthma among short and long sleepers than in optimal sleepers. CONCLUSIONS Short and long sleepers with central obesity and underweight status were associated with significantly higher prevalence of asthma than optimal sleepers in Chinese adults.OBJECTIVE Sleep Apnea Syndrome (SAS) is frequently comorbid with Restless Legs Syndrome (RLS). Both disorders are associated with disturbed sleep. However, data about insomnia specific symptoms in patients suffering from both sleep disorders (SAS-RLS) are rare. METHODS In a restrospective design, we investigated 202 patients suffering from SAS and SAS-RLS. All patients underwent polysomnography, performed a vigilance test (Quatember-Maly), and completed the Regensburg Insomnia Scale (RIS), Epworth Sleepiness Scale (ESS), Beck Depression Inventory-II (BDI-II), and a Morning Questionnaire (FZN). Differences in insomnia specific symptoms between SAS and SAS-RLS were calculated using ANOVA. In a secondary analysis, the differences in daytime sleepiness and depression were analyzed. RESULTS Of 202 patients, 42 (21%) had SAS-RLS. The proportion of women (60%) with SASRLS was higher than for men (40%) while men had had a higher proportion (71%) of SAS alone compared to women (29%), p less then 0.0005. The RIS score was higher in SAS-RLS than in SAS. Envonalkib No differences were found in PSG data, ESS, BDI-II, or vigilance tests. CONCLUSIONS Patients with both disorders SAS and RLS show a higher degree of insomnia-specific symptoms than for SAS alone and may profit from additional insomnia specific treatment.Fragmented ultramafic bodies in New England were important mineral resources until the early twentieth century, yet few studies have addressed their potential to release trace metals to terrestrial and aquatic environments. Here, we evaluate the release of four trace metals (Cr, Co, Mn, and Ni) from a historic serpentine-talc "soapstone" quarry in Blandford, MA, USA. Soil pits, sediment and rock samples, and stream water samples were collected from upslope undisturbed areas, within the mine spoils and mine face, and downslope of the mine. In order to provide a bottom-up approach for understanding metal release, careful petrographic analysis, electron-dispersive spectroscopy, and wavelength-dispersive spectroscopy were employed to provide first-order insight into the mineralogy of the deposit and a determination of potential metal-bearing phases. Trace metals were primarily observed in ultramafic sheet silicates, primary Fe-oxides, and interstitial weathering-related sulfates. Bulk rock concentrations were Cr (1550 mg kg-1), Co (230 mg kg-1), Mn (1100 mg kg-1), and Ni (1960 mg kg1); Cr, Co, and Ni were elevated relative to the surrounding country rock. However, soils and sediments total concentrations were comparable to background soil concentrations Cr (119 mg kg-1), Co (73 mg kg-1), Mn (894 mg kg-1), and Ni (65 mg kg-1). Moreover,  less then  0.5% of the total concentrations were bioavailable (0.1 M ammonium acetate extraction), implying that metals are present as insoluble forms. However, ~ 20% of the total Cr, Mn, Ni, and Co concentrations were strong acid extractable, suggesting mobilization over the coming decades. Stream water concentrations of Mn and Cr were  less then  50 µg L-1, below concentrations outlined by USEPA drinking water standards, and WHO water guidelines for Ni. These results suggest that transport of Cr, Mn, Ni, and Co from the serpentine-talc as dissolved compounds or sediments is limited by retention within silicate and oxides.This study aims to evaluate available Cu and Zn levels in soil and related in soil organic matter (SOM) fractions (fulvic acids-FA, humic acids-HA, and humins-HU) after 10 years of application of pig slurry (PS) and pig deep litter (PL). Soil samples were collected from an experiment with black oat/corn succession under no-tillage in southern Brazil. The treatments consisted of fertilization of 90 and 180 kg N ha-1 applied as PS and PL from 2002 to 2012 and a control treatment without any fertilization. SOM chemical fractionation was performed in air-dried samples. Copper and Zn concentrations were analyzed in soil (total, EDTA- and CaCl2-extracted) and in SOM fractions. The amount of Cu and Zn (in mol) related to each fraction of SOM (Cu/C and Zn/C molar ratios) was established. The applications of PS and PL promoted the accumulation of total and available Cu and Zn, especially in the PL180 treatment. The highest amount of Zn was found with HU, while for Cu both HA and HU were important retention compartments. The highest Cu/CFA, Cu/CHA and Cu/CHU ratios were found with the addition of PL. Increases in Zn/C ratio were found mainly in FA fraction. The high levels of Cu and Zn obtained in the HCl-extracted SOM fraction suggest that a considerable part is bound to SOM and clay minerals with low energy. However, the SOM is an important source of metal adsorption in soils with swine manure application.Technical vehicle inspection centers are widespread in Kuwait. All vehicles should pass the test every 2 years if not older than 6 years or every 1 year for other vehicles. This study provided an insight into the data collected from test centers and the emission test utilized in Kuwait. Data were collected from test centers in the six Kuwaiti governorates. European standards were selected as limits for emission violations. Independent variables included the place of vehicle manufacture, vehicle's age, and odometer reading. A multinomial logit model was used to identify the significant predictors and determine the correlation between dependent and independent variables. Artificial neural network was employed to compare prediction estimates of neural network and multinomial logit. The findings showed that the place of vehicle's manufacture, vehicle's age, and odometer reading were significant regarding violating emission standards of carbon monoxide (CO). Asian vehicles, vehicles with more than 150,000 km mileage, and vehicles older than 15 years had a higher probability of failing the CO test compared to the place of manufacture.

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