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We propose an updated design on concentrated thermionic emission solar cells, which demonstrates a high solar-to-electricity energy conversion efficiency larger than 10% under 600 suns, by harnessing the exceptional electrical, thermal, and radiative properties of the graphene as a collector electrode. By constructing an analytical model that explicitly takes into account the non-Richardson behavior of the thermionic emission current from graphene, space charge effect in vacuum gap, and the various irreversible energy losses within the subcomponents, we perform detailed characterizations on the conversion efficiency limit and parametric optimum design of the proposed system. Under 800 suns, a maximum efficiency of 12.8% has been revealed, where the current density is 3.87 A cm-2, output voltage is 1.76 V, emitter temperature is 1707 K, and collector temperature is 352 K. Moreover, we systematically compare the peak efficiencies of various configurations combining diamond or graphene, and show that utilizing diamond films as an emitter and graphene as a collector offers the highest conversion efficiency, thus revealing the important role of graphene in achieving high-performance thermionic emission solar cells. This work thus opens up new avenues to advance the efficiency limit of thermionic solar energy conversion and the development of next-generation novel-nanomaterial-based solar energy harvesting technology.728 simulated microdosimetric lineal energy spectra (26 different ions between 1H and 238U, 28 energy points from 1 to 1000 MeV/n) were used in combination with a recently-developed biological weighting function (Parisi et al., 2020) and 571 published in vitro clonogenic survival curves in order to 1) assess prediction intervals for the in silico results by deriving an empirical indication of the experimental uncertainty from the dispersion in the in vitro hamster lung fibroblast (V79) data used for the development of the biophysical model; 2) explore the possibility of modeling the relative biological effectiveness (RBE) of the 10% clonogenic survival of asynchronized normoxic repair-competent mammalian cell lines other than the one used for the development of the model (V79); 3) investigate the predictive power of the model through a comparison between in silico results and in vitro data for 10 ions not used for the development of the model. https://www.selleckchem.com/Bcl-2.html At first, different strategies for the assessment of the in silico prediction intervals were compared. The possible sources of uncertainty responsible for the dispersion in the in vitro data were also shortly reviewed. Secondly, also because of the relevant scatter in the in vitro data, no statistically-relevant differences were found between the RBE10 of the investigated different asynchronized normoxic repair-competent mammalian cell lines. The only exception (Chinese Hamster peritoneal fibroblasts, B14FAF28), is likely due to the limited dataset (all in vitro ion data were extracted from a single publication), systematic differences in the linear energy transfer (LET) calculations for the employed very-heavy ions, and the use of reference photon survival curves extracted from a different publication. Finally, the in silico predictions for the 10 ions not used for the model development were in good agreement with the corresponding in vitro data.Recent demonstrations of metasurfaces present their great potential to implement flat and multifunctional optical elements, which are accomplished with the designs of planar optics and micro-/nano- fabrications. Integrating metasurfaces in three dimensions has manifested drastically increasing advantages in manipulating light fields by extending design freedom. However, fabricating three dimensional metasurfaces remain a tough challenge due to the lack of stereo printing protocols. Herein, we demonstrate laser nanoprinting of floated silver nanodot array in transparent hydrogel films for 3D metasurface to achieve color patterning. It is found that spatially resolved nanodots can be produced through laser induced photoreduction of silver ions and robustly anchored to the gel backbones by a focused femtosecond laser beam within a pH-responsive smart hydrogel matrix. With the aid of expansion properties of the pH-responsive hydrogel, repetitive coloration of the patterned plasmonic nanodot array over a wide spectrum range is achieved via reversible regulation of nanodot spacing from 550 to 350 nm and vice versa. This approach allows broadband 3D color-regulation in nanoscale for applications in active spectral filtering, information encryption and security tagging, etc.Anodic titanium oxide (ATO) photonic crystals (PhCs) are promising for photonics, photocatalysis, and solar cells. A refractive index modulation in ATO PhCs is caused by the modulation of porosity and, thus, the latter should be controlled precisely. The ATO cell walls etching in electrolyte solution during anodizing increases the porosity of the PhC structure and shifts the photonic band gap (PBG) position to shorter wavelengths. Until now, the ATO cell walls etching in organic based electrolytes has been associated solely with the chemical dissolution of ATO in fluoride-containing solution. Here, a significant enhancement of cell walls etching is observed when electric current flows under anodic polarization. This effect leads to the blue shift of the PBG position of ATO PhCs with the number of periods. Therefore, it is essential for the synthesis of ATO PhCs with a precise PBG position.Until now, the growth of periodic vertically aligned multi-walled carbon nanotube (VA-MWCNT) arrays was dependent on at least one lithography step during fabrication. Here, we demonstrate a lithography-free fabrication method to grow hexagonal arrays of self-standing VA-MWCNTs with tunable pitch and MWCNT size. The MWCNTs are synthesized by plasma enhanced chemical vapor deposition (PECVD) from Ni catalyst particles. Template guided dewetting of a thin Ni film on a hexagonally close-packed silica particle monolayer provides periodically distributed Ni catalyst particles as seeds for the growth of the periodic MWCNT arrays. The diameter of the silica particles directly controls the pitch of the periodic VA-MWCNT arrays from 600 nm to as small as 160 nm. The diameter and length of the individual MWCNTs can also be readily adjusted and are a function of the Ni particle size and PECVD time. This unique method of lithography-free growth of periodic VA-MWCNT arrays can be utilized for the fabrication of large-scale biomimetic materials.Radiation therapy treatments are typically planned based on a single image set, assuming that the patient's anatomy and its position relative to the delivery system remains constant during the course of treatment. Similarly, the prescription dose assumes constant biological dose-response over the treatment course. However, variations can and do occur on multiple time scales. For treatment sites with significant intra-fractional motion, geometric changes happen over seconds or minutes, while biological considerations change over days or weeks. At an intermediate timescale, geometric changes occur between daily treatment fractions. Adaptive radiation therapy is applied to consider changes in patient anatomy during the course of fractionated treatment delivery. While traditionally adaptation has been done off-line with replanning based on new CT images, online treatment adaptation based on on-board imaging has gained momentum in recent years due to advanced imaging techniques combined with treatment delivery systems. Adaptation is particularly important in proton therapy where small changes in patient anatomy can lead to significant dose perturbations due to the dose conformality and finite range of proton beams. This review summarizes the current state-of-the-art of on-line adaptive proton therapy and identifies areas requiring further research.

Epiretinal prostheses are designed to restore vision to people blinded by photoreceptor degenerative diseases by stimulating surviving retinal ganglion cells (RGCs), which carry visual signals to the brain. However, inadvertent stimulation of RGCs at their axons can result in non-focal visual percepts, limiting the quality of artificial vision. Theoretical work has suggested that axon activation can be avoided with current stimulation designed to minimize the second spatial derivative of the induced extracellular voltage along the axon. However, this approach has not been verified experimentally at the resolution of single cells.

In this work, a custom multi-electrode array (512 electrodes, 10 μm diameter, 60 μm pitch) was used to stimulate and record RGCs in macaque retina ex vivo at single-cell, single-spike resolution. RGC activation thresholds resulting from bi-electrode stimulation, which consisted of bipolar currents simultaneously delivered through two electrodes straddling an axon, were compared to activation thresholds from traditional single-electrode stimulation.

On average, across three retinal preparations, the bi-electrode stimulation strategy reduced somatic activation thresholds (~21%) while increasing axonal activation thresholds (~14%), thus favoring selective somatic activation. Furthermore, individual examples revealed rescued selective activation of somas that was not possible with any individual electrode.

This work suggests that a bi-electrode epiretinal stimulation strategy can reduce inadvertent axonal activation at cellular resolution, for high-fidelity artificial vision.

This work suggests that a bi-electrode epiretinal stimulation strategy can reduce inadvertent axonal activation at cellular resolution, for high-fidelity artificial vision.Brachytherapy is a mature treatment modality. The literature is abundant in terms of review articles and comprehensive books on the latest established as well as evolving clinical practices. The intent of this article is to part ways and look beyond the current state-of-the-art and review emerging technologies that are noteworthy and perhaps may drive the future innovations in the field. There are plenty of candidate topics that deserve a deeper look, of course, but with practical limits in this communicative platform, we explore four topics that perhaps is worthwhile to review in detail at this time. First, intensity modulated brachytherapy (IMBT) is reviewed. The IMBT takes advantage of anisotropic radiation profile generated through intelligent high-density shielding designs incorporated onto sources and applicators such to achieve high quality plans. Second, emerging applications of 3D printing (i.e., additive manufacturing) in brachytherapy are reviewed. With the advent of 3D printing, interest in this torrow's reality. The future is bright for brachytherapy.We report a systematic study of the magnetic phase diagram in the H-T plane, negative magnetization, exchange interactions and field-induced spin-flop transitions in the distorted perovskite Y1-xCexCrO3. Locked AFM and weak-FM configurations in Γ4(Gz, Fy, Ax) phase of YCrO3(S = 3/2 ground state) unlocks into the Γ2(Fz, Gy, Cx; FzR,CxR) phase of canted AFM and FM structures with the dilute substitution of Ce (x≥ 0.05). The asymmetric and symmetric exchange interactions (JAS~ 0.11 meV and JS~ 0.85 meV) between the trivalent Ce and Cr enable the positive quartic-anisotropy field (HK4~ 2.85 × 102Oe) along with the second order anisotropy field (HK2~ 5.93 × 102Oe). Unlike the pristine YCrO3compound, the Ce incorporated system exhibits a giant fourth-order anisotropy constant (K4= 1.35 × 105erg/cc) due to the asymmetric exchange interaction between the trivalent Ce-Cr which further lifts the free energy of the system and causes lag in the onset of AFM ordering showing the significant thermal hysteresis (ΔT ~ 10 K) in the field-cooled-warming measurement protocol as compared to the field-cooled-cooling mode.