Clineself4722

Health-Risk Behaviours (HRBs) are significant antecedent conditions of adverse health outcomes among adolescents, and their prevention requires an in-depth understanding of associated factors. Cefodizime Like any other behaviour, HRBs may be an outcome of a complex interplay between personal and situational factors that determines our responses. Among other factors, emotional tendencies, specific behavioural patterns, and psychosocial environment may be the significant factors working at different hierarchical positions within a system and guiding human behaviours, including HRBs. Previous studies have explored the role of these specific factors in developing and maintaining HRBs, but mainly among the adult population, and no conclusive results could be observed regarding their contribution to HRBs in adolescents. The present study explored the predictability of adolescents' engagement in HRBs with regard to three representations of the mentioned factors, i.e., emotion regulation difficulties, perceived parenting practices and personality traits. A total of 723 (Males = 440) adolescents (Mage = 16.05, SD = 1.1) provided relevant information on the standardized questionnaires. Structural equation modelling was applied to test the stated hypotheses. Analysis revealed that the adolescents who reported more difficulty regulating one's emotions, perceived parenting practice as maladaptive, scored high on neuroticism and low on conscientiousness, showed more engagement in HRBs than their counterparts. Further, the findings indicated that emotion regulation difficulties and perceived parenting practices are stronger predictors of HRBs than personality traits. Interventional programs targeting HRBs among adolescents should address specific facets of emotional dysregulation and sensitise parents about their role in moderating adolescents' HRBs.The Palestinian community in Israel has experienced significant stressors historically, yet little research has assessed the strategies these individuals cope with stress. The COVID-19 pandemic provided an opportunity to assess coping resources among Palestinian adults. The present study explored the religious and personal resources adopted by Palestinians living in Israel to cope with the stress caused by the COVID-19 outbreak, and whether differences in using these resources were attributed to selective demographic variables. The sample consisted of 985 Palestinian adults, 58% of whom are women and 42% are men. Participants' ages ranged from 18 to 50 years old (M = 35.8, SD =14.48), and they were chosen using convenience sampling from the Palestinian community living in Israel. Participants completed self-report questionnaires to report on their personal resources for coping with stress. Palestinian adults who participated in this study tended to rely more on faith in God, optimism, social and family support, having the self-control and self-efficacy, as well as subjective well-being, as resources for coping caused by crises like the COVID-19 pandemic. Also, there were significant differences on these coping resources that attributed to selective demographic variables. The findings were discussed with relation to previous studies.Previous studies have revealed that adverse childhood experiences (ACEs) create a significant and lasting effect of increased anxiety. However, few studies have examined the mediating and moderating mechanisms underlying this relation. The present study aimed to explore the mediating role of self-compassion and moderating role of social support in ACEs-anxiety relationship among Chinese adolescents. In this cross-sectional study, 1,764 middle school students completed questionnaires measuring their levels of ACEs, anxiety, self-compassion (SC), and social support. Correlations of variables were computed using Pearson's r. Mediation and moderated mediation models were tested using PROCESS macro with the regression bootstrapping method. After covariates (age and gender) were controlled, results showed that (1) ACEs were positively associated with anxiety symptoms; (2) self-compassion partially mediated the ACEs-anxiety association; (3) both ACEs-anxiety and SC-anxiety relationships were moderated by social support. Specifically, social support was associated with lower anxiety, particularly among students with fewer ACEs or lower level of self-compassion. Reducing possible adversities existing in environment may help to reduce risk of anxiety for adolescents. Cultivating self-compassion is crucial for adolescents' mental health, since it may play a role in ACEs-anxiety relationship. Social support would operate as a buffer to ACEs in the relation with anxiety, under the circumstances of mild adversities, and a promoter to self-compassion in the relation with anxiety, under the circumstances of low self-compassion.This research aims to analyze brand communication and brand image as specific drivers of wine brand preference and their influence on wine consumers' intention to visit associated wineries. Specifically, this paper enhances the understanding of the roles of advertising-promotion, sponsorship-public relations, corporate social responsibility, and social media in brand communication, as well as functional, emotional and reputation components in brand image development in the context of wine tourism industry. Data was collected through a structured and self-administered questionnaire from 486 visitors to wineries in Spain. Partial least squares regression was used to evaluate the measurement model and the hypotheses. The empirical analysis shows that brand communication and brand image have similar positive effects on brand preference, and that brand image mediates the relationship between brand communication and brand preference. This research suggests implications for theory and practice relative to brand management in terms of communication and image; and it proposes insights into novel communication tools and marketing activities for the winery tourism industry. Firms should employ a holistic evaluation of brand communication to involve the whole organization, which would enhance the strategic role that brand communication plays.

The online version contains supplementary material available at 10.1007/s12144-021-02656-w.

The online version contains supplementary material available at 10.1007/s12144-021-02656-w.Parents recognize the potential benefits of technology for their young children but are wary of too much screen time and its potential deficits in terms of social engagement and physical activity. To address these concerns, related literature suggests technology usages with a blend of digital and physical learning experiences. Towards this end, we developed Kid Space, incorporating immersive computing experiences designed to engage children more actively in physical movement and social collaboration during play-based learning. The technology features an animated peer learner, Oscar, who aims to understand and respond to children's actions and utterances using extensive multimodal sensing and sensemaking technologies. To investigate student engagement during Kid Space learning experiences, an exploratory case study was designed using a formative research method with eight first-grade students. Multimodal data (audio and video) along with observational, interview, and questionnaire data were collected and analyzed. The results show that the students demonstrated high levels of engagement, less attention focused on the screen (projected wall), and more physical activity. In addition to these promising results, the study also enabled us to understand actionable insights to improve Kid Space for future deployments (e.g., the need for real-time personalization). We plan to incorporate the lessons learned from this preliminary study and deploy Kid Space with real-time personalization features for longer periods with more students.Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The global scientific community faces a significant challenge in developing targeted therapies to combat the SARS-CoV-2 infection. Computational approaches have been critical for identifying potential SARS-CoV-2 inhibitors in the face of limited resources and in this time of crisis. Main protease (Mpro) is an intriguing drug target because it processes the polyproteins required for SARS-CoV-2 replication. The application of Ayurvedic knowledge from traditional Indian systems of medicine may be a promising strategy to develop potential inhibitor for different target proteins of SARS-CoV-2. With this endeavor, we docked bioactive molecules from Triphala, an Ayurvedic formulation, against Mpro followed by molecular dynamics (MD) simulation (100 ns) to investigate their inhibitory potential against SARS-CoV-2. The top four best docked molecules (terflavin A, chebulagic acid, chebulinic acid, and corilagin) were selected for MD simulation study and the results obtained were compared to native ligand X77. From docking and MD simulation studies, the selected molecules showed promising binding affinity with the formation of stable complexes at the active binding pocket of Mpro and exhibited negative binding energy during MM-PBSA calculations, indication their strong binding affinity with the target protein. The identified bioactive molecules were further analyzed for drug-likeness by Lipinski's filter, ADMET and toxicity studies. Computational (in silico) investigations identified terflavin A, chebulagic acid, chebulinic acid, and corilagin from Triphala formulation as promising inhibitors of SARS-CoV-2 Mpro, suggesting experimental (in vitro/in vivo) studies to further explore their inhibitory mechanisms.This paper studies the problem of principal-agent with moral hazard in continuous time. The firm's cash flow is described by geometric Brownian motion (hereafter GBM). The agent affects the drift of the firm's cash flow by her hidden effort. Meanwhile, the firm rewards the agent with corresponding compensation and equity which depend on the output. The model extends dynamic optimal contract theory to an inflation environment. Firstly, the authors obtain the dynamic equation of the firm's real cash flow under inflation by using the Itô formula. Then, the authors use the martingale representation theorem to obtain agent's continuation value process. Moreover, the authors derive the Hamilton-Jacobi-Bellman (HJB) equation of investor's value process, from which the authors derive the investors' scaled value function by solving the second-order ordinary differential equation. Comparing with He[1], the authors find that inflation risk affects the agent's optimal compensation depending on the firm's position in the market.Migration plays a crucial role in epidemic spreading, and its dynamic can be studied by metapopulation model. Instead of the uniform mixing hypothesis, we adopt networked metapopulation to build the model of the epidemic spreading and the individuals' migration. In these populations, individuals are connected by contact network and populations are coupled by individuals migration. With the network mean-field and the gravity law of migration, we establish the N-seat intertwined SIR model and obtain its basic reproduction number ℛ 0 . Meanwhile, we devise a non-markov Node-Search algorithm for model statistical simulations. Through the static network migration ansatz and ℛ 0 formula, we discover that migration will not directly increase the epidemic replication capacity. But when ℛ 0 > 1 , the migration will make the susceptive population evolve from metastable state (disease-free equilibrium) to stable state (endemic equilibrium), and then increase the influence area of epidemic. Re-evoluting the epidemic outbreak in Wuhan, top 94 cities empirical data validate the above mechanism.