Bakermcdonald3806

This research examined the impact of sexual orientation on heterosexuals' judgment of parental competence. Using a vignette approach, Study 1 presented participants with a lesbian, gay, or heterosexual couple who desired to have a child, either as adoptive parents or, in an additional heterosexual target condition, as biological parents. see more Study 2 presented a lesbian, gay, or heterosexual parent couple; heterosexual targets were either adoptive parents, reflecting the LG target conditions, or biological parents. Contradicting Hypothesis 1, neither target sexual orientation nor way to parenthood (with the latter varied in the heterosexual target condition only) had an impact on parental competence attributions. Confirming Hypothesis 2, participants with personal contact with lesbian and gay (LG) people provided higher ratings of LG target parental competence, mediated by positive attitudes toward homosexuality. Importantly, this mediation did not occur in the heterosexual target condition, corroborating the specificity of the intergroup contact effect.Understanding how religion and well-being are related for lesbian and bisexual women provides important context for clinical interventions. Current literature in the field diverges on whether the relationship between religious commitment and well-being is positive for those in the queer community. The current study examines whether an independent or interdependent self-construal explains the relationship between religious commitment and eudaimonic well-being (EWB) for lesbian and bisexual women. This empirical study used data from the Multi-Site University Study on Identity and Culture, a research collaboration amongst 30 colleges and universities in the United States. Findings suggest that although self-construal does not mediate the relationship between religious commitment and well-being, there are significant effects between religious commitment and EWB as well as an independent self-construal and EWB. These findings provide a deeper understanding of variables associated with greater well-being and are important for the advancement of research and practice with queer women.The synapse is a highly specialized and dynamic structure, which is involved in regulating neurotransmission. Nerve cell adhesion molecule is a kind of transmembrane protein that mediates the interaction between cells and cells, cells and extracellular matrix, and plays a role in cell recognition, metastasis, and transmembrane signal transduction. Among nerve cell adhesion molecules, Neurexins (NRXNs) and Neuroligins (NLGNs) have been focused due to the relation with autism and other neuropsychiatric diseases. The previous research discovered numerous variants in NRXNs and NLGNs reported in neurodevelopmental disorders by genomic sequencing. However, structural variants in synaptic molecules caused by genome variants still prevent us from understanding the molecular mechanism of diseases. Thus, we sought to conduct a comprehensive risk assessment of the known NRXN and NLGN gene variants by protein structure analysis. In this study, we analyzed the structural properties of the NRXN/NLGN complex by calculating free energy in residue scanning, in combination with existing risk evaluation tools to focus on candidate missense mutations. Our calculations show that five candidate missense mutations in NLGNs can reduce the stability of NLGNs and even prevent the formation of NRXN/NLGN complexes, namely R87W, R204H, R437H, R437C and R583W. In addition, we found that the affinity of the amino acid substitution (Leu593Phe) (ΔΔG(affinity)) changes the affinity of the NLGN dimer. Overall, we have identified important potential pathological variants that provide clues to biomarkers.Communicated by Ramaswamy H. Sarma.To achieve a more sustainable waste-to-energy (WTE) process, the recycling of solid waste incineration (MSWI) bottom ash (BA) has received large attention nowadays. This study investigated how WTE BA form is changed after the hydration and the impacts of WTE BA hydration on its leaching characteristics by using geometrical and leaching tests when incorporated in cement matrix for the recycling. The material composition and characteristics of anhydrous BA, hydrated BA, cement paste, Portland cement concrete (PCC), and BA-combined PCC were evaluated through scanning electron microscopy, X-ray spectroscopy and X-ray diffraction analyses. The results confirmed that the WTE BA newly formed a complex phase of hydration products in a cement matrix. Synthetic precipitation leaching procedure (SPLP) test was also conducted to investigate the leaching behaviors of alkaline components and metals of BA in the crushed BA-PCC samples. Through the leaching study, the leachability of crushed BA-combined concrete was rigorousment mixture can form new mineralogical phases of hydration products in cement matrices such as Copper Hydrogen Arsenate Hydrate and Jahnsite. A significant reduction of alkaline elements (Si, Al, and K) from crushed PCC mixed with WTE BA due to the hydration. The lowest concentrations of major alkaline elements leached from the crushed PCC containing either 10% or 20% of BA contents. The averaged leaching concentration of detected elements is substantially below the water quality guidelines (provided by U.S. EPA and WHO) except Al.After acquired brain injury (ABI) many patients suffer from persistent cognitive and emotional disturbances. The aim of this study was to investigate the treatment outcome of an integrated intervention, combining neuropsychological and cognitive behavioural therapy (nCBT), against waitlist (WL) in outpatients with ABI. Individuals seeking outpatient treatment for cognitive and emotional problems after ABI were randomly allocated to nCBT (n = 27) or WL (n = 29) and completed assessments at baseline, post-treatment/WL and at six-month follow-up. The primary outcome measures were general psychopathology and functional activity in daily life. The nCBT group showed significant improvement for general psychopathology post-treatment when compared to WL. nCBT was also superior to WL regarding the secondary outcomes, i.e., the reduction of negative affect and the improvement of quality of life. No significant differences for functional activity and community integration were observed. Significant pre-post effect sizes ranged between small for functional activity and medium for quality of life.