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Follicular cysts, endometrioid and periovarian cysts were found to belong to the 0 elastotype. Cysts of the corpus luteum belonged to the II elastotype on the Ueno scale. The lowest values of the stiffness index were seen in follicular and periovarian cysts, and the highest value was observed in endometrioid cysts. Our results have shown that ultrasound examination of ovarian tumors is an accurate and highly informative method.By changing the lifestyle and increasing the cancer incidence, accurate diagnosis becomes a significant medical action. Today, DNA microarray is widely used in cancer diagnosis and screening since it is able to measure gene expression levels. Analyzing them by using common statistical methods is not suitable because of the high gene expression data dimensions. So, this study aims to use new techniques to diagnose acute myeloid leukemia. In this study, the leukemia microarray gene data, contenting 22283 genes, was extracted from the Gene Expression Omnibus repository. Initial preprocessing was applied by using a normalization test and principal component analysis in Python. Then DNNs neural network designed and implemented to the data and finally results cross-validated by classifiers. The normalization test was significant (P>0.05) and the results show the PCA gene segregation potential and independence of cancer and healthy cells. The results accuracy for single-layer neural network and DNNs deep learning network with three hidden layers are 63.33 and 96.67, respectively. Using new methods such as deep learning can improve diagnosis accuracy and performance compared to the old methods. It is recommended to use these methods in cancer diagnosis and effective gene selection in various types of cancer.Although benefiting from an unprecedented technological evolution, contemporary endodontics is still characterized by the recurrence of retreatments, due to the need to solve quite frequent incidents, accidents, or even failures of primary endodontic treatment. This survey aims to assess both the etiology and the prevention methods of one of the most troublesome endodontic iatrogenies instrument separation during root canal shaping. The multifactorial nature of this occurrence entails identifying and taking into account all the causal and contributing factors. Their significant number and the possible involvement of any of them, starting with the complexity and variability of the root canals and ending with the technical specifications concerning the nickel-titanium rotary instrumentation system being used, highlight the necessity to develop valid guidelines to avert the occurring of such an upsetting situation.The study of the incidence of cryoglobulinemia is relevant in patients with an intestinal anastomotic leak. This study aims to determine a laboratory marker of the risk of small intestine anastomotic leak. The study was based on 96 patients who were subjected to resections of segments of the small intestine with the formation of intestinal anastomoses at the State Institution "Zaytsev V.T. Institute of General and Urgent Surgery of National Academy of Medical Sciences of Ukraine". Of all the operated patients, there were 55.2% women and 44.8% men. Of the 96 patients examined, cryoglobulinemia was detected in the majority - 62.5% of patients, of which 4 were later proved to have inactive hepatitis C; the remaining 38.5% had no cryoglobulinemia. According to the existing theory of the autoimmune mechanism of postoperative surgical complications formation, the revealed decrease in the level of cryoglobulins on the second day could be related to their fixation in the microcirculatory bed and the development of immunocomplex inflammation. While the increase in the content of cryoglobulins in serum on the third day can be caused by their entry into the circulatory bed from deposition or fixation sites and the development of a secondary immune response. In patients with intestinal anastomosis failure after resection of intestinal segments, cryoglobulinemia rates increased more than 80 mg/l; this indicator could be used as a marker of postoperative complications.Transformational management properties could make the weakest organizations strong with the right and efficient approach build. The aim of this study was to determine the transformational management properties among hospital managers in Gonbad-e-Kavus. In terms of data collection, the present study is an an applied research involving objective and descriptive-analytical surveys. The statistical population includes all staff hospitals that were selected randomly in Gonbad-e-Kavous city. The present study was performed including 7 hospitals and 346 respondents. Castiglion transformational management properties questionnaire (2006) was used to collect the required data, with Cronbach's alpha coefficient (0.946). Based on the findings of the research, 67.3% (233 subjects) of the participants in the study evaluated the transformational management properties of the managers of the hospitals at a good level (with a score of 140. 76 ± 27.76), with Payambar Hospital having the highest (151.57 ± 20.31) and Taleghani Hospital the lowest score (130.22 ± 28.10) attributed to the management properties affecting change management. Based on the findings of the research and the impact of effective transformational management properties among the managers of the understudy hospitals, it is recommended to form all effective management transformational management properties, through founding special educational units and holding classes for hospital managers, in order to form various skills and competencies such as communication skills, skills to influence others, trusting, attention skills, and providing sufficient independence which all play an essential role in the success of managers and pave the ground for the flourishment of transformation and innovation in the hospitals.Flatfoot is a common deformity in the pediatric population and has a multitude of causes. Sometimes, it can be a normal finding in children, and treatment should not be guided only based on the appearance, but rather after thoroughly assessing the patient and the impact it has on the child's daily life. In this paper, we describe the quality of life that the patients are experiencing after the surgical treatment of this pathology. We made a comparison between the most used techniques for correcting flatfoot and insisted on the postoperative comfort of the patient, rehabilitation, and the time it took to get back to their daily routine. The comparison was made between Mosca calcaneal lengthening osteotomy, Grice extraarticular arthrodesis, arthroereisis and triple arthrodesis of the foot. All of the surgeries were performed by the same doctor at "Grigore Alexandrescu" Emergency Hospital for Children in Bucharest. From the data collected, we propose that newer, minimally invasive techniques could be used in treating this pathology in order to help the patient feel better in the postoperative period and avoid some of the complications regularly encountered when using the old techniques.Chronic obstructive pulmonary disease is a multifactorial disease characterized by gene-gene interaction as well as environmental effects. The incidence of type 2 diabetes mellitus is proved to be higher in the presence of chronic obstructive pulmonary disease than in the case of its absence. We aimed to study the genotypes of MDR1 (C3435T) gene polymorphism and its relationship with clinical, instrumental, and laboratory parameters in chronic obstructive pulmonary disease associated with type 2 diabetes mellitus. All the patients were divided into two groups. The first group included 53 patients with chronic obstructive pulmonary disease, and the second group included 49 patients with chronic obstructive pulmonary disease with comorbid type 2 diabetes mellitus. The COPD assessment test (CAT), 6-minute walk test, BODE integral index, spirometry, and bioimpedansometry were used for examination. Lipid spectrum, carbohydrate metabolism, endothelial functional status, leptin, adiponectin, and serum levels were also determined by means of enzyme immunoassay. Our study results showed no significant difference between the genotypes of the control group of healthy individuals and patients with chronic obstructive pulmonary disease and comorbid type 2 diabetes mellitus. Though, a certain association of this gene polymorphism with clinical findings by CAT-test, specific parameters of carbohydrate (fasting glucose) and lipid metabolism (total cholesterol and low-density cholesterol lipoproteins), endothelial functional state (nitrate/nitrite level) with the minor allele T available was found.Surgery site infection is one of the most common postoperative complications which is associated with increased morbidity, mortality and admission costs. It is considered a priority to determine the level of nosocomial infection and its control in reflecting the quality of care. Therefore, this study aimed to evaluate the microbial contamination after cardiac surgery at a hospital cardiac surgery ward of Besat Hospital, Tehran. In this cross-sectional descriptive-analytic study (2013-2017), 610 patients underwent surgery at the Department of Cardiac Surgery of Besat Hospital. All necessary information such as urine culture, surgical site, histopathologic examination for the diagnosis of microbial contamination and microorganisms were collected from the patient records and inserted in the questionnaire. The data were analyzed using SPSS (version 25). The incidence of nosocomial infections following cardiac surgery reportedly ranged from 17% to 23%. Accordingly, pneumonia (51.2%) and local infections (22%) were the most common infections in the studied population. selleck chemicals llc The mortality rate in our population was 11.4%. Moreover, 64.3% of the total mortality cases were reported in patients with sepsis. The mean age and duration of admission of patients with catheter infection were significantly higher than other subjects. Given the relatively high prevalence of the infection and its importance, it is necessary to take more serious measures to prevent and control these infections.Implant-prosthetic rehabilitation registers multiple variants, but their short- and long-term evolution has been a frequent concern. This study aimed to evaluate the peri-implant bone resorption at the level of the tilted implants in the SKY fast & fixed restorations, with reference to clinical and treatment parameters. An observational study was conducted on a convenience sample of patients with implant-prosthetic rehabilitation in one or both jaws, according to the SKY fast & fixed protocol (Bredent, Germany). Bone resorption was assessed on panoramic radiography. Other data were collected from the patient's medical records. Thirty tilted implants were analyzed, 12 of which were in the maxilla and 18 in the mandible. After the follow-up period, both bone resorption (maximum 7 mm) and bone apposition (maximum 8 mm) were observed. There was a tendency for the resorption to be more pronounced in the mandible, in patients where tooth loss was due to periodontal disease, and when implants with length less than 16 mm were used.