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Genes FGFR2, MSX1, MATN1, MYOH1, ACTN3, GHR, KAT6B, HDAC4, AJUBA were found to be positively linked to skeletal class II malocclusion.

Out of the 11 studies included, a positive correlation of the genes with the skeletal II malocclusion was found in 10 studies. Genes FGFR2, MSX1, MATN1, MYOH1, ACTN3, GHR, KAT6B, HDAC4, AJUBA were found to be positively linked to skeletal class II malocclusion.

Early childhood caries (ECC) is one of the most common diseases in the children of developing countries, affecting their oral health-related quality of life. From an economic perspective, silver diamine fluoride (SDF) can limit the progression of active carious lesions.

To estimate and compare the loss of shear bond strength among two adhesive materials on SDF-treated demineralized primary teeth dentin.

Laboratory setting and in-vitro study design.

For the in-vitro study, 40 primary teeth indicated for extraction were selected. The demineralization solution was 5% nitric acid. The samples were divided into four groups, Group 1 - GIC Type IX, Group 2 - Self-etch (SE) adhesive + G-Aenial Universal Flo, Group 3 - SDF + GIC Type IX, and Group 4 - SDF + SE adhesive + G-Aenial Universal Flo.

Descriptive analysis and analysis of variance with Tukey's Post hoc test.

The shear bond strength of GC G-Aenial Universal Flo(18.8165 ± 13.0448 MPa) found to be superior to GIC (5.7845 ± 1.8968 MPa). However, bond strength was significantly reduced with GC G-Aenial Universal Flo(34.0441 ± 14.1949/18.8165 ± 13.0448 MPa) compared to GIC (7.7956 ± 2.2804/5.7845 ± 1.8968 MPa) following the application of SDF.

It was concluded that SE adhesive + GC G-Aenial Universal Flois the material with better shear bond strength compared to GIC Type IX with and without SDF. Considering the severity and prevalence of ECC, socioeconomic strata of Indian population, the choice of material for masking the discoloration, and prevention of disease, GIC can be suggested as an alternative over GC G-Aenial Universal Flo.

It was concluded that SE adhesive + GC G-Aenial Universal Flois the material with better shear bond strength compared to GIC Type IX with and without SDF. Considering the severity and prevalence of ECC, socioeconomic strata of Indian population, the choice of material for masking the discoloration, and prevention of disease, GIC can be suggested as an alternative over GC G-Aenial Universal Flo.

A successful root canal treatment involves the elimination of microorganisms, and prevents them from reinfecting the root and/or peri-radicular tissues. This can be mainly achieved by efficient cleaning and shaping of the root canal system. Due to the complexity of the root canal morphology, hand and rotary files cannot clean areas such as the isthmuses and lateral canals. In such cases, effective irrigation and the use of intracanal medicaments are essential. Medicaments that are applied should be removed before obturation.

To evaluate the efficacy of passive ultrasonic irrigation in the removal of three different intracanal medicaments - Triple antibiotic paste (TAP), Odontopaste, and Metapex using a stereomicroscope.

A total of 45 single-rooted human teeth were selected and decoronated. The root canals were shaped with ProTaper rotary files. The specimens were fixed in modified Eppendorf vials with silicone material. The roots were split longitudinally, and a standardized groove was prepared in the apical part. The teeth were randomly divided into three groups each containing 15 samples based on the intracanal medicament used TAP, Odontopaste, and Metapex.

The root halves were reassembled with sticky wax and remounted in the Eppendorf vial. Each specimen was irrigated with 3% NaOCl and agitated using a passive ultrasonic device. The root segments were disassembled. Digital images were obtained using a stereomicroscope.

The data were evaluated statistically using Kruskal-Wallis and Mann-Whitney U tests. There was a statistically significant difference in the remaining intracanal medicament score (P < 0.05).

Odontopaste showed the least remaining amount score, whereas TAP and Metapex showed greater retention within the dentin.

Odontopaste showed the least remaining amount score, whereas TAP and Metapex showed greater retention within the dentin.

Research on dentin remineralisation protocols in particular 'biomimetic remineralisation' has gained huge momentum. Aim of this study was to evaluate if biomimetic analogs, incorporated in n-HAp, as an experimental formulation could aid in remineralization of artificial caries-like dentin and have anti-microbial effect on cariogenic bacteria, S mutans.

An experimental paste was formulated using nano-hydroxyapatite (nHAp) with Non-Collagenous Protein analogs- polyacrylic acid (PAA), sodium tri-poly phosphate (STPP) with Simulated Body Fluid. Partially demineralised dentin specimens were divided into three groups (n=10) based on the remineralisation treatment as, Group A- n-HAp paste, Group B- n-HAp and NCP analogues and Group C (Control) - no treatment. At the end of the experimental period, the specimens were assessed using SEM-EDS analysis and Vickers microhardness testing. Further, the antimicrobial efficacy of the paste was assessed.

The results were statistically analyzed using ANOVA with post-hoc Bonferroni test.

Dentin specimens treated with the experimental paste revealed greater tubular occlusion, with intra tubular deposits and increased mineral content. Specimens treated with n-HAp alone had higher microhardness values and inhibitory effect on the cariogenic bacteria.

Non-Collagenous Protein analogs incorporated in n-HAp could remineralize the demineralised dentin and had antibacterial efficacy against S mutans.

Non-Collagenous Protein analogs incorporated in n-HAp could remineralize the demineralised dentin and had antibacterial efficacy against S mutans.

Poly-methyl methacrylate (PMMA) is an universally acceptable denture base material. Efforts are made to increase the applications with the addition of new constituents. Chitosan has established antifungal properties. The mechanical properties of Chitosan-denture base composite is less evaluated in the literature. This study estimates the differences in impact strength of material for different concentrations of chitosan-reinforced denture base resins.

The study estimated the differences in IZOD impact strength of denture base resin reinforced with 0%, 5%, 10% and 15% of chitosan by weight.

The acrylic samples were fabricated in according to ISO 180 regulations. The study had four test groups (n = 10). ACh0 was the control group with no reinforcements. ACh5, ACh10 and ACh15 had chitosan reinforcement of 5%, 10% and 15% by weight. The samples were processed by conventional heat polymerization cycle and tested in IZOD impact testing machine. Infigratinib mouse The data were recorded and statistically analyzed with Kruskal-Wallis test.

The mean impact strength was high in ACh5 (4.25 ± 1.05 kJ/m

) compared to ACh0 (2.88 ± 0.60 kJ/m

), ACh10 (3.63 ± 0.40 kJ/m

), ACh15 (3.38±0.60 KJ/m

). Statistically significant differences between the test groups was determined by Kruskal-Wallis and post hoc Bonferroni test (Chi-square = 12.843, P = .005, df = 3).

The impact strength of denture base resin increased with 5% chitosan compared with other percentage of chitosan. No statistical significant relationship was observed between the groups.

The impact strength of denture base resin increased with 5% chitosan compared with other percentage of chitosan. No statistical significant relationship was observed between the groups.

The aim of this 12 week, single-blind clinical trial was to compare the efficacy of Manual (Oral-B Pro Health Gum care

), Powered (Oral-B Cross action Power Dual

) and Charcoal (Colgate slim Soft Charcoal

) toothbrushes in plaque control.

60 systemically healthy students were selected at random among the students of a Dental College, living under similar environment and dietary conditions. Plaque and calculus were removed professionally and three varieties of toothbrush were distributed among them. Plaque index (PI), sulcus bleeding index (SBI) and gingival index (GI) were assessed at baseline, 3, 6 and 12 weeks. Assessment of colony forming units (CFU) was done at baseline and 12

week. The learning effect over a period of time was also assessed.

Over the 12-week period, PI reduced significantly (P < 0.001) with % reduction in plaque from 47% to 59%, 41% to 53% and 45% to 55% for manual, powered and charcoal brush. A significant reduction in GI and SBI was also seen with all the brushes. An insignificant difference in PI, GI and SBI was seen between the brushes. CFU count before and after brushing reduced gradually and statistically significantly (P < 0.001) for all the brushes; however, by end of 12

week period, there was no significant difference (P > 0.05). The learning effect increased from 35% to 60%, 24% to 56% and 31% to 58% for three brushes, respectively, but was more pronounced for powered brush.

It can be concluded that all the three brushes (manual, powered and charcoal) are clinically effective in removing plaque, with learning effect more pronounced for powered brush and if proper technique is followed, no brush is superior to the other.

It can be concluded that all the three brushes (manual, powered and charcoal) are clinically effective in removing plaque, with learning effect more pronounced for powered brush and if proper technique is followed, no brush is superior to the other.

Aesthetic concerns due to dental fluorosis (DF) considerably impact pyschosocial health in young children and requires aesthetic microinvasive treatment.

The aim of this study was to use quantitative light-induced fluorescence to evaluate two intervention protocols microabrasion with resin infiltration and microabrasion with remineralization and assess which brings about more fluorescence gain; better colour masking and greater patient satisfaction among subjects with dental fluorosis.

120 maxillary central incisors with Grade 3 DF (Dean's Fluorosis Index) were randomly distributed into four groups I-microabrasion + resin infiltration (fluorosis with stains); II microabrasion + remineralization (fluorosis with stains); III-microabrasion + resin infiltration (fluorosis without stains); IV microabrasion + remineralization (fluorosis without stains). At baseline, post-microabrasion and post-intervention Quantitative light-induced fluorescent images were captured. Fluorescence gain (ΔF) was analysed from thervention.

The aim of this study was to compare audio-visual and verbal education on oral health related quality of life, dental anxiety and dental neglect, on diabetes mellitus patients attending Teerthanker Mahaveer Hospital, Moradabad.

The current longitudinal interventional study was conducted to check the efficiency of audio-visual and verbal education on OHRQoL, Dental anxiety and dental neglect, on diabetes mellitus patients attending Teerthanker Mahaveer Hospital, Moradabad, U.P., India. A 14-item questionnaire, OHIP-14, with emphasis on seven proportions of impact was used to collect information on OHRQoL. Corah Dental Anxiety Scale (DAS) will be used to collect data on Dental Anxiety. A prevalidated revised proforma of Dental Neglect Scale (DNS) was used to gather information on Dental Neglect. The questionnaire was a six-question instrument related to dental problems. After collecting the initial baseline data, the sample was divided into two groups verbal education group (n = 1030) and audio-visual education group (n = 1030).

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