Kvistholden0711
We discuss possible applications of robots in this context through four scenarios. These scenarios are meant as 'food for thought' for the research community which we hope will inspire future research. We discuss risks and concerns for using social robots in clinical practice. This article concludes by highlighting the potential advantages as well as limitations of integrating social robots in conventional interventions to improve accessibility and standard of care as well as outlining future steps in relation to this research direction. Clearly recognizing the need for future empirical work in this area, we propose that social robots may be an effective component in robot-assisted interventions for social anxiety, not replacing, but complementing the work of clinicians. We hope that this article will spark new research, and research collaborations in the highly interdisciplinary field of robot-assisted interventions for social anxiety.During the 60 years since the first scientific reports about a relation between aflatoxin exposure and adverse health consequences, both in animals and humans, there has been a remarkable number of basic, clinical and population science studies characterizing the impact of this mycotoxin on diseases such as liver cancer. Many of these human investigations to date have focused on populations residing in Asia and Africa due to the high incidence of liver cancer and high exposures to aflatoxin. These studies formed the basis for the International Agency for Research on Cancer to classify the aflatoxins as Group 1 known human carcinogens. In addition, aflatoxin contamination levels have been used in international commodity trade to set the price of various staples such as maize and groundnuts. While there have been many case-control and prospective cohort studies of liver cancer risk over the years there have been remarkably few investigations focused on liver cancer in Latin America. Our interdisciplinary and multiple institutional collaborative has been developing a long-term strategy to characterize the role of aflatoxin and other mycotoxins as health risk factors in Guatemala and neighboring countries. This paper summarizes a number of the investigations to date and provides a roadmap of our strategies for the near term to discern the emergent etiology of liver cancer in this region. With these data in hand public health-based prevention strategies could be strategically implemented and conducted to lower the impact of these mycotoxins on human health.This study aims to verify differences in the subjective well-being of 10 and 12 years old Brazilian boys and girls over time using data from the First (2012) and the Third (2019) Wave of Brazilian data collection on Children's Worlds research. Participants of the first wave were 2,338 children (M = 11.08 years old, 55.3% girls) and of the third wave, they were 1,787 children (M = 11.33 years old, 55.3% girls). We performed a Multivariate Analysis of Variance (MANOVA) with subjective well-being scales (OLS, PWI-SC and BMSLSS) used as dependent variables, and age, gender and times of measurement (wave of data collection) were used as independent variables. Main results present that there are significant reductions of all subjective well-being means over time (from 2012 to 2019) regardless gender and age. These results denounce the profound changes in contexts associated with diminished investment in education, access to health, social care and children's rights' policies overall in Brazil and reinforce the perspective that children's participation in society is essential for the development of public policies that represent their current needs.The current COVID-19 (SARS-CoV-2) pandemic has generated negative psychological effects on the global population. SPOP-i-6lc concentration In this context, one of the most vulnerable groups is adolescents, who have faced a range of challenging scenarios. The consequences of this pandemic for the wellbeing of adolescents need to be researched across countries. From this perspective, this study aims to characterize the wellbeing of adolescents from Mexico and Chile during the pandemic and delve into the relationship between victimization and the hedonic and eudaimonic types of wellbeing. Data from adolescent students (n = 3,275) were used, with the support of the Global Research Alliance. Descriptive and regression analyses were conducted and their results indicated that 1) Late adolescents scored lower on flourishing, and males scored higher than females. There was also a higher prevalence of languishing in late adolescents from both countries, as well as high levels of languishing in non-binary adolescents, especially in Chile; 2) There was a high prevalence of poly-victimization, with the highest percentage reported by females and the late adolescent group in both countries; 3) Non-victims had a higher probability of being in the flourishing group than victims in both countries; 4) Poly-victimization especially had an effect on the eudaimonic wellbeing of early adolescents and on the hedonic and eudaimonic wellbeing of late adolescents in both countries. Implications related to the mental health policies for adolescence are discussed in terms of how to increase adolescent wellbeing.
The study quantitatively investigated the related research progress in pharmaceutical sciences/pharmacy education from a bibliometric angle and provided feasible suggestions to facilitate the development of pharmaceutical sciences/pharmacy postgraduate education.
Bibliometric analysis was conducted using the database of Web of Science Core Collection. The literature published in 1985-2021 was screened and selected. The overall profile description, citation analysis, and research hotspot mining were performed using the citation report of Clarivate Analytics, bibliometrics online platform, and VOSviewer software. The bibliometric results and profiles were plotted and illustrated.
The bibliometric analysis of 485 papers of interest showed that the research frontier was continuously expanding; especially the institutions from the USA were the main contributors. The numbers of citing papers have been ascending, and a considerable part of citations were from the areas other than the education research. Mining results showed that the in-school and residency education of pharmacy postgraduates was a research hotspot, as well as interprofessional training and new education styles for Coronavirus Disease 2019 (COVID-19) therapy were the emerging trends in the field.
Through the analysis of the studies, it was found that encouraging relevant research programs, establishing financial supports, and launching specified publication sources could be helpful to boost the development of pharmaceutical sciences/pharmacy postgraduate education. Besides, the results suggested that this was a less discussed topic and was worthy for the investigators to pay more attention to such an issue.
The online version contains supplementary material available at 10.1007/s12247-021-09611-z.
The online version contains supplementary material available at 10.1007/s12247-021-09611-z.Measurement of adolescent life satisfaction across cultures has not received much attention in previous empirical research. The present study evaluated measurement invariance of the Satisfaction with Life Scale (SWLS) among adolescents in 24 countries and regions (N = 22,710; age range = 13-19 years; 53% female). A single-factor model with residual covariance between a pair of items tapping past life satisfaction fitted well in 19 countries and regions and showed a partial metric invariance. In a subset of nine countries and regions, partial scalar invariance was supported. Partial metric invariance across all 24 countries and regions was achieved when custom model modifications in five countries and regions were included. Three SWLS items showed evidence of noninvariance across cultures. The measurement model was found to operate similarly across gender and age. Our findings suggest that caution is needed when using the SWLS for measuring life satisfaction among adolescents from different cultures.
The online version contains supplementary material available at 10.1007/s11482-021-10024-w.
The online version contains supplementary material available at 10.1007/s11482-021-10024-w.In this paper, a new fault diagnosis approach based on elite opposite sparrow search algorithm (EOSSA) optimized LightGBM is proposed. It is necessary to extract appropriate features when dealing with high-dimensional data. Since the distribution of the high-dimensional data is not always approximately subject to a normal distribution, it will cause errors when it is approximated to normal distribution for feature extraction. The dimension reduction algorithms based on Euclidean distance often ignore the change of data distribution. To address this problem, cam locally linear discriminate embedding (CLLDE) based on cam weighted distance is proposed, which can improve the performance dealing with the deformed data of locally linear discriminate embedding (LLDE). The performance of CLLDE is better than LLDE on the iris dataset. It is important to establish a classifier with optimized hyper-parameters for fault identification. Sparrow search algorithm (SSA) is a novel optimization algorithm, which has achieved good results in many applications, but its optimization ability and convergence speed still need to be improved. Elite opposite sparrow search algorithm (EOSSA) is proposed by introducing elite opposite learning strategy and orifice imaging opposite learning strategy into SSA. The optimization results on benchmark functions show that EOSSA converges faster and has better optimization ability compared with the other five algorithms. EOSSA is used to optimize the hyper-parameters of LightGBM to train a classifier that can obtain a better fault recognition rate. Finally, the effectiveness of the proposed fault diagnosis approach is verified on Tennessee Eastman (TE) process dataset. Experiment results demonstrate that the EOSSA-LightGBM-based approach is superior to other algorithms.
Systemic capillary leak syndrome (SCLS) is arare and often fatal clinical entity used to describe ageneralized increase in vascular permeability leading to fluid extravasation toward the interstitial compartment. SCLS could be an idiopathic disease or secondary to infections, malignancies or drugs.
We present acase of presumably granulocyte colony-stimulating factor (G-CSF)-induced SCLS in a21-year-old man diagnosed with T‑lymphoblastic leukemia/lymphoma. He received the 6thcycle (partB) of the hyper-CVAD chemotherapeutic regimen followed by the initiation of neutropenic fever prophylaxis protocol which included antibiotics and G‑CSF. In acourse of hours, the patient became dyspneic, hypotensive, and edematous which required intensive care unit admission and was stabilized accordingly. In the following days the patient's anasarca progressively increased which was associated with hypoalbuminemia, hypotension and anemia with pericardial and bilateral plural effusions. As adiagnosis of exclusion augmented by the acuity of such clinical event, observed concomitantly with the administration of the prophylaxis protocol, the suspicion of G‑CSF-induced SCLS was established. Consequently, G‑CSF was discontinued and treatment with dexamethasone and intravenous immunoglobulins (IVIG) was started. The patient's condition improved significantly illustrated by hemodynamic stability in addition to improvement regarding the anasarca, hypoalbuminemia, and anemia. Follow-up scans suggest resolution of the pericardial and plural effusions.
SCLS remains a serios and potentially fatal complication of G‑CSF administration which should be taken into consideration, since such medication is widely utilized in oncology wards.
SCLS remains a serios and potentially fatal complication of G‑CSF administration which should be taken into consideration, since such medication is widely utilized in oncology wards.
