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LIF/LIFR oncogenic signaling can be a fresh healing targeted throughout endometrial most cancers.
Background The double role of caregiver-employee (CE) defines those workers who simultaneously serve as an informal, unpaid care provider for sick, disabled, or elderly relatives, and it is a situation that is on the increase in most western countries. Providing informal caregiving can lead to detrimental effects on emotional well-being and several physical and psychological diseases (e.g., caregiver-burden). CEs can suffer double discomfort (at work and at home), but, first of all, they can be exposed to a high level of home-to-work conflict (HWI). In this study, we analyzed the CE phenomenon in a typical Italian public company, where the mean age of workers is particularly high. Methods An online questionnaire related to the perception of HWI, well-being, and discomfort at work (depression, emotional exhaustion, job engagement) in relation to the family load (none, parents with less then 12 children to care for, caregiver to other adults, or children and older adults to care for/old/children to care for emerso, Sottimano, Viotti and Guidetti.Real causal systems are complicated. Despite this, causal learning research has traditionally emphasized how causal relations can be induced on the basis of idealized events, i.e., those that have been mapped to binary variables and abstracted from time. For example, participants may be asked to assess the efficacy of a headache-relief pill on the basis of multiple patients who take the pill (or not) and find their headache relieved (or not). In contrast, the current study examines learning via interactions with continuous dynamic systems, systems that include continuous variables that interact over time (and that can be continuously observed in real time by the learner). To explore such systems, we develop a new framework that represents a causal system as a network of stationary Gauss-Markov ("Ornstein-Uhlenbeck") processes and show how such OU networks can express complex dynamic phenomena, such as feedback loops and oscillations. To assess adult's abilities to learn such systems, we conducted an experiment in which participants were asked to identify the causal relationships of a number of OU networks, potentially carrying out multiple, temporally-extended interventions. click here We compared their judgments to a normative model for learning OU networks as well as a range of alternative and heuristic learning models from the literature. We found that, although participants exhibited substantial learning of such systems, they committed certain systematic errors. These successes and failures were best accounted for by a model that describes people as focusing on pairs of variables, rather than evaluating the evidence with respect to the full space of possible structural models. We argue that our approach provides both a principled framework for exploring the space of dynamic learning environments as well as new algorithmic insights into how people interact successfully with a continuous causal world. Copyright © 2020 Davis, Bramley and Rehder.Young children help others in a range of situations, relatively indiscriminate of the characteristics of those they help. click here Recent results have suggested that young children's helping behavior extends even to humanoid robots. However, it has been unclear how characteristics of robots would influence children's helping behavior. Considering previous findings suggesting that certain robot features influence adults' perception of and their behavior toward robots, the question arises of whether young children's behavior and perception would follow the same principles. click here The current study investigated whether two key characteristics of a humanoid robot (animate autonomy and friendly expressiveness) would affect children's instrumental helping behavior and their perception of the robot as an animate being. link2 Eighty-two 3-year-old children participated in one of four experimental conditions manipulating a robot's ostensible animate autonomy (high/low) and friendly expressiveness (friendly/neutral). Helping was assessed in an out-of-reach task and animacy ratings were assessed in a post-test interview. Results suggested that both children's helping behavior, as well as their perception of the robot as animate, were unaffected by the robot's characteristics. The findings indicate that young children's helping behavior extends largely indiscriminately across two important characteristics. These results increase our understanding of the development of children's altruistic behavior and animate-inanimate distinctions. Our findings also raise important ethical questions for the field of child-robot interaction. Copyright © 2020 Martin, MacIntyre, Perry, Clift, Pedell and Kaufman.Background Research on desired emotions revealed that individuals want to feel negative emotions if they expect these emotions to yield certain benefits. In previous studies, the pursuit of sadness (e.g., via pursuing art that evokes sadness) has been attributed to hedonic motives, i.e., to feel pleasure. We propose that in individuals with major depressive disorder (MDD) the pursuit of sadness may be more strongly related to self-verification motives, i.e., to sustain their sense of self through feeling sad. Methods Participants with MDD (n = 50) were compared to non-depressed controls (n = 50) in their desired emotional states, as indicated by selected music (sad, happy and neutral), and in their motives (hedonic vs. self-verification) for choosing sad music. Groups were also compared in their self-reported general preference for sadness and the perceived functionality of sadness. Results MDD participants showed a significant higher desire for sadness; more than half of them deliberately chose sad music. Whereas MDD participants had a marked preference for self-verification over hedonic motives, the reverse was true for non-depressed controls. MDD participants also agreed more strongly with self-verifying functions of sadness and expressed a stronger general preference for sadness. Conclusion Findings indicate that emotion regulation in MDD might be driven by self-verification motives. They point to the relevance of exploring patients' desired emotional states and associated motives. The systematic integration of positive affect into the self-image of depressed patients might help to deemphasize the self-verifying function of sadness, thereby overcoming the depression. Copyright © 2020 Arens and Stangier.Gender differences in achievement exhibit variation between domains and between countries. Much prior research has examined whether this variation could be due to variation in gender equality in opportunities, with mixed results. Here we focus instead on the role of a society's values about gender equality, which may have a more pervasive influence. We pooled all available country measures on adolescent boys' and girls' academic achievement between 2000 and 2015 from the Program for International Student Assessment (PISA) and Trends in International Mathematics and Science Study (TIMSS) assessments of math, science, and reading. We then analyzed the relation between gender differences and country levels of gender egalitarian values, controlling for country levels of living standards and indicators of gender equality in opportunities. Gender egalitarian values came out as the most important predictor. Specifically, more gender egalitarian values were associated with improved performance of boys relative to girls in the same countries. This pattern held in reading, where boys globally perform substantially worse than girls, as well as in math and science where gender differences in performance are small and may favor either boys or girls. Our findings suggest a previously underappreciated role of cultural values in moderating gender gaps in academic achievement. link3 Copyright © 2020 Eriksson, Björnstjerna and Vartanova.Objective The current randomized controlled trial investigated the effectiveness of a job crafting intervention program on work engagement as the primary outcome and job crafting as the secondary outcome among Japanese employees. link2 Methods Participants who met the inclusion criteria were randomly assigned to an intervention group (n = 138) or a control group (n = 143). The job crafting intervention program provided only to the intervention group consisted of two 120-minute group sessions with e-mail or letter follow-up. Outcomes were assessed at baseline and at 3-month and 6-month follow-up in both groups. Results In the total sample, the job crafting intervention program showed a non-significant effect on work engagement at both 3-month and 6-month follow-up. Also, job crafting did not improve significantly. link2 However, the program showed a significant intervention effect on work engagement (p = 0.04) with small effect size (Cohen's d = 0.33 at 3-month follow-up) of workers in a lower job crafting subgroup. Conclusion The job crafting intervention program may not be sufficiently effective to improve work engagement and job crafting for the entire sample of participants. However, it may be effective for workers in lower job crafting subcategories. Clinical Trial Registration UMIN Clinical Trials Registry (www.umin.ac.jp/ctr/), identifier UMIN000026668. Copyright © 2020 Sakuraya, Shimazu, Imamura and Kawakami.In psychodynamic psychotherapy, verbal (structures and intents) and non-verbal (voice and interruptions) dimensions of communication intertwine conveying information and determining the mutual regulation between therapist and patient through conversational sequences. The communication components interplay is the foundation for building the therapeutic alliance, a relational dimension that predicts a psychotherapy outcome and change, influenced by patient-therapist exchanges from the initial stages of their encounter. Depressed patients present specific verbal and non-verbal communication and show difficulties in developing and maintaining the therapeutic alliance. Based on the reviewed literature, the main aim of this study was to analyze how the action of specific communicative modes, implemented by the therapist and depressed patients, affect the reciprocal construction of the early therapeutic alliance by each participant during the mutual regulation processes. We employed a mixed methods approach based onin communication-alliance interactions), and polar coordinate analysis (to identify significant relationships between communicative modes and alliance ruptures and repairs). Results confirm that the therapist's verbal (asking and exploring) and non-verbal (elaborating and cooperatively interrupting) modes and the depressed patients' verbal (asserting and exploring) and non-verbal (expressing emotions and cooperatively interrupting) modes determine stable patterns and significant associations with collaborative behaviors connected to the reciprocal construction of alliance by each participant. link3 All this may provide professionals with useful information to increase the psychotherapy effectiveness with depressed patients. Copyright © 2020 Del Giacco, Anguera and Salcuni.Climate change is statistical, abstract and difficult to comprehend directly. Imagining a specific, personal episode where you experience consequences of climate change in the future (episodic future thinking) may bring climate change closer, thus increasing the perceived risk of climate-related risk events. We conducted an experiment to test whether episodic future thinking increased the perceived risk of climate-related risk events and climate change in general, as compared to thinking about the future in a general, abstract manner (semantic future thinking). We also tested whether this effect is moderated by how easy it is to imagine the specific climate-related risk event initially. link3 Participants were randomly assigned to an episodic future thinking-condition or a semantic future thinking-condition, and two of the risk events in each condition were related to flooding (difficult to imagine) and two were related to extreme temperature (easy to imagine). The results show no main effect of episodic future thinking on perceived risk, and no interaction effect with imaginability.