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The results showed that advanced coagulation-based processes (such as peroxicoagulation) and studies focusing on improving membrane-based processes through reduction of membrane fouling are focal points which will be trending into the future.The side effects from the use of plant protection products and their potential effects on non-target arthropods (NTAs) such as honey bees, other insects within the vegetation layer and epigeic arthropods nowadays receive more attention. However, uncertainties about the factors driving the deposition of active substances (a.s.) into off-crop areas persist, in particular during sowing of treated seeds. Analysing a highly standardised 8-year field experiment, we assessed the importance of various factors potentially affecting dust drift and deposition of a.s., emitted during the sowing process of treated seeds and deposited on fields adjacent to the drilling field, i.e. on the ground, on flowers, and on nonflowering plant parts. Regarding a.s. deposition, the Heubach a.s. value has a predictive capability, which is independent from all other factors taken into account in this study, and can thus be considered as a scenario-independent measure of potential dust deposition. Petri dish samplers, an established standard method for measuring a.s. deposition, were representative of the results from the plant samplers for a given combination of drilling technique and adjacent crop type. Adjacent crop type is likely to impact on a.s. deposition. The present work will enable a more field-realistic exposure assessment for bees and other NTAs.In the process of coal gangue surface accumulation and underground filling disposal, the heavy metals contained in coal gangue will inevitably precipitate out and migrate, which will cause serious environmental pollution. Seventy-five gangue samples of different geological ages are obtained from 25 coal mines in China. The contents of Hg, Pb, Cd, Cr, As, Cu, Zn, Mn, Se, and Be in gangue samples are determined. The enrichment coefficients of heavy metal elements in coal gangue are analyzed. The formation of heavy metal elements in gangue is studied by cluster analysis and principal component analysis. The results showed that the contents of Pb, Se, and As in gangue samples formed in Late Carboniferous and Early Permian are highest; the contents of Cr, Cd, Be, Cu, and Zn in gangue samples formed in Late Permian are highest. The later the formation age of coal gangue, the lower the overall enrichment of heavy metal elements. The contents of Cu, Be, Cd, Zn, and Cr in coal gangue are mainly controlled by sedimentation. Brepocitinib in vivo The contents of Pb and Se are mainly affected by the affinity between heavy metal elements in coal gangue. The affinity between Mn and other heavy metal elements is weak, and sulfur had a certain influence on the content of Mn.Monitoring water body quality parameters with high spatial and temporal resolutions is crucial because mitigation of pollution is usually costlier than early prevention/intervention. The existing monitoring methods for irrigation ponds in Taoyuan, Taiwan, are based on field measurements that have low spatial and temporal resolutions. In this study, using Landsat 8 satellite imagery, a multiple regression-derived relationship between the satellite band reflectance and the concentration of total phosphorus (TP) was established. The satellite imagery was atmospherically corrected with ACOLITE based on shortwave infrared (SWIR) bands. This method was used to select predictor variables in the multiple regression-derived equation based on forward selection of variables using a p value and variation inflation factor (VIF) threshold. The derived equation yielded a coefficient of determination (R2) of 0.67. The near-infrared band (band 5) was found to be most significant. The Landsat 8 imagery retrieved for two of the three pond studies included only a few pixels from the ponds because parts of the pond surfaces are covered by floating photovoltaic power plants. The TP concentrations resulting from the derived equation indicate the feasibility of using satellite remote sensing methods to monitor the water quality. The derived relationships are potentially applicable to extend the availability of temporal and spatial water quality data for these irrigation ponds.To achieve allowable gas emission limits and eliminate the high cost and challenges associated with pre-treatment of sludge before incineration, a new technique was proposed to co-incinerate wet printing and dyeing sludge with different calorific values of coal while conducting a full evaluation of organic and inorganic emission of pollutants. Different proportions (0%, 10%, 20%, 30%, 40%) of the wet sludge-coal slurry (peat) were incinerated using a commercialized fluid bed (circulating) incinerator. The results showed the that flue gas emitted contained sulfur oxides (SOx), nitrogen oxides (NOx), polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), polychlorinated biphenyls (PCBs), and heavy metals in bottom ash. The ΣPCBs content produced from the 7 congeners was 6.4014 μg/m3 with more than 65% below tetra-chlorinated biphenyls which are the most harmful and persistent. An increment in the sludge (peat) ratio caused the content of SOx to decrease drastically, while the content of NOx exhibited two maxima. The heavy metal concentrations of Cd, Zn, Mn, Pb, Fe, Ni, Cr, and Cu decreased with increasing sludge ratio. The leaching toxicity of heavy metals in the bottom ash proved to be lower than the limit values for hazardous waste. The PCDD/F 1-TEQ emissions of the flue gas increased from 0.06844 to 0.10779 ng/m3 as the proportion of sludge increased in peat. The I-TEQ values of the PCDD/Fs showed a slight increment with increasing sludge ratio. The sum of the PCDD/Fs (ideally at 20-30%) does not exceed the 0.1ng/Nm3 of the EU and the 0.5 ng TEQ/Nm3 of the new Chinese emissions standard. link2 Statement of novelty Different calorific values of coal of different proportions were incinerated with wet printing and dyeing sludge in order to achieve the new allowable gas emission limits, tap heat energy and eliminate high cost.The Fundão Dam collapsed, on November 5th, 2015, dumping more than 50 million/m3 of iron ore tailings, enriched with metals, into the Doce River channel. The objective of this study was to evaluate the reproductive biology and histological damage in Astyanax lacustris specimens exposed to the metals from the dam collapse. The study was carried out at Doce River, in Espírito Santo State, Brazil. link3 Monthly samplings were carried out for a year. Astyanax lacustris had multiple spawning females' reproductive peak was in September, October, November, and December; and males between September, October, January, and February. There was a latency in the formation of gonads. For male gonads, it was necessary a 6 cm growth for it to increase from 30 to 50% and 4 cm for female gonads to increase from 40 to 50%. There is a positive correlation between gonad's concentration of Al and Fe and the rate of histological damage in females. Male gonads had a high rate of immature cells invading the cell lumen (47.36%) and female gonads showed a higher frequency of atresia (39.64%). Fish exposed to the contaminated water showed moderate-high gonad histological damage. The observed changes can directly influence the organism's development and reproduction in the long run, thus affecting A. lacustris population present in the region.In order to enhance degradation of harmful organic pollutants like Rhodamine B (RhB) dye under visible-light irradiation (λ >420 nm), a silver iodide/reduced graphene oxide/bismuth molybdate (AgI/rGO/Bi2MoO6) Z-scheme heterojunction photocatalyst was synthesized by a solvothermal process combined with an in-situ precipitation technique. The AgI (15 wt.%)/rGO/Bi2MoO6 (AGBMO-15) photocatalyst with a dosage of 0.5 g/L exhibited the highest photocatalytic activity with 98.0% RhB removal under an initial concentration of 10 mg/L within 30 min. This removal rate was approximately 65.8%, 57.7%, and 72.7% higher than that for a rGO/Bi2MoO6 (GBMO) binary composite, pure AgI powder, and pristine Bi2MoO6 nanoplates, respectively. The novel photocatalyst achieved approximately three times higher photocatalytic degradation within a shorter period of visible-light irradiation than pure Bi2MoO6. Through photoluminescence analysis and trapping experiments, this outstanding performance was attributed to the efficient separation of photogenerated electron-hole pairs owing to an internal electric field at the contact interface of AgI and Bi2MoO6, which generated more superoxide radical anions (•O2-) as primary reactive species to promote RhB degradation. Meanwhile, the rGO participated in the capture of visible-light and played a role of solid electronic medium at the AgI/Bi2MoO6 interface, which realized an effective Z-scheme electron transfer path, avoided the self oxidation of photocatalyst and prolonged the carrier life. Furthermore, the AGBMO-15 photocatalyst exhibited excellent photocatalytic degradation stability, maintaining an RhB removal rate of 96.2% after four cycles of reuse. Due to its simplicity, reusability, and controllability, the proposed photocatalyst has excellent application potential for the environmental remediation of wastewater.Hollow fiber systems (HFSs) have been widely applied to study pharmacokinetic-pharmacodynamic (PK-PD) relationships in antibiotic research and development. The system comprises a bundle of high-density hollow capillary fibers that conduct a flow of medium with or without drug and an extra-capillary space (ECS) inoculated with the pathogen of interest. The semipermeable membrane of the hollow fibers allows for rapid exchange of small molecule drugs and solutes, while the pathogen is restricted to the ECS. The unique properties of the HFS are (1) the ability to simulate any PK profile within the fibers and ECS, including plasma or site-of-disease PK profiles, (2) the ability to simultaneously input several drugs with different half-lives, (3) the ability to manipulate growth conditions such as medium composition, carbon source, and pH, and (4) the ability to sample in both compartments in order to monitor drug concentrations and bacterial growth kinetics over time. The system is particularly suited for Mycobacterium tuberculosis research in a biosafety level 3 (BSL3) environment since pathogenic bacteria are sequestered in an isolated compartment. The HFS was qualified by the European Medicines Agency for antituberculosis drug development in 2015. Here, we describe the standard procedures used to study the growth kinetics of M. tuberculosis in the HFS and the killing effect of first-line antituberculous drugs applied under simulated human PK conditions. This animal-sparing and economical tool can be applied to optimize dosing schedules that minimize emergence of resistance and to prioritize drug regimens that accelerate sterilization.Treatment of tuberculosis necessitates combination therapy. Therefore, development of new tuberculosis therapies should consider multidrug effects because specific combinations may improve or reduce treatment efficacy through synergistic or antagonistic drug interactions, respectively. The standard assay of drug interactions is a checkerboard assay, wherein the drug-dose combinations are well-sampled across broad dose ranges. However, measuring three or more drugs in combination with a checkerboard assay is impractical due to the high number of measurements. We describe a protocol for efficient and quantitative measurement of drug interactions called diagonal measurement of n-way drug interactions (DiaMOND). DiaMOND is a geometric optimization of the checkerboard assay, using only the diagonal and axes of the checkerboard. This protocol describes how to perform DiaMOND experiments and analysis for Mycobacterium tuberculosis growth inhibition in standard growth conditions. As a guide on how to customize the DiaMOND assay, this protocol includes notes to modify the procedures for other growth conditions and outcome measures.

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