Kiddmcdowell8996
Obstacles encountered when maintaining excellent dispensing practices for children include a lack of age-appropriate dosage forms, a shortage of medications in appropriate strengths for children, a lack of appetizing drugs, and a lack of competence in pediatric pharmacy. These difficulties contribute to ineffective dispensing procedures and an urgent need to study whether oral dose forms of medications are dispensed to children in a rational way.
The purpose of this study is to evaluate the rational dispensing of oral dosage forms of medicines to children, as well as the factors that influence this practice.
Using validated indicators, a cross-sectional study design was utilized to analyze the rational dispensing practice of oral dosage forms of medicines administered to children under the age of 12 years in seven pharmacies and two drug stores over a one-month period.
Out of 810 medicines, 11.7% and 4% were irrationally manipulated, 5.8% and 1.8% needed manipulation, 3.7% and 0.2% were alternatively dispensed, 8.8% and 7.5% of the medicines had correct advice on their label and also 745 medicines were adequately labeled in the hospital and the selected drug stores. In this study, 92% of medicines were adequately labeled and had sufficient advice on their labels, 15.3% of medicines were irrationally manipulated and around 7.7% of the dosage forms needed manipulation during dispensing. The type of medicine retail outlet had a significant effect on the percentage of instances where alternative solid oral dosage forms were dispensed (p = 0.003), the percentage of dosage forms were adequately labeled (p = 0.008), and the percentage of dosage forms were irrationally manipulated before dispensing (p = 0.001).
The rational dispensing practice of oral dosage forms of medicines was relatively poor and there is room for improvement.
The rational dispensing practice of oral dosage forms of medicines was relatively poor and there is room for improvement.
Physicians can limit upward trending healthcare costs, yet legal and ethical barriers prevent the use of direct financial incentives to engage physicians in cost-reduction initiatives. Physician-directed reinvestment is an alternative value-sharing arrangement in which a health system reinvests a portion of savings attributed to physician-led cost reduction initiatives back into professional areas of the physicians' choosing. Formal evaluations of such programs are lacking.
To understand the impact of Stanford Health Care's physician-directed reinvestment in its first year (2017-2018) on physician engagement, adherence to program requirements around safety and fund use, and factors facilitating program dissemination, semi-structured qualitative interviews with physician participants, non-participants, and administrative stakeholders were conducted July-November 2019. Interview transcripts were qualitatively analyzed through an implementation science lens. To support contextual analysis of the qualitative onsibilities. Administrative data excluding physician time, which was not directly compensated, showed a direct cost savings of $8.9M. This implied an 11-fold return on investment excluding uncompensated physician time.
A physician-directed reinvestment program appeared to facilitate latent frontline physician innovation towards value, though additional evaluation is needed to understand its long-term impact.
A physician-directed reinvestment program appeared to facilitate latent frontline physician innovation towards value, though additional evaluation is needed to understand its long-term impact.
Microorganisms contribute to the pathogenesis of obstructive sleep apnea (OSA)-associated hypertension (HTN), while more studies focus on intestinal microbiome. However, the relationship between oral microbiota and OSA-associated HTN has yet to be elucidated. This study aimed to identify differences in salivary microbiota between patients with OSA comorbid HTN compared with OSA patients, and furthermore evaluate the relationship between oral microbiome changes and increased blood pressure in patients with OSA.
This study collected salivary samples from 103 participants, including 27 healthy controls, 27 patients with OSA, 23 patients with HTN, and 26 patients with OSA comorbid HTN, to explore alterations of the oral microbiome using 16S rRNA gene V3-V4 high-throughput sequencing. And ultra-high-performance liquid chromatography was used for metabolomic analysis.
Alpha- and beta-diversity analyses revealed a substantial difference in community structure and diversity in patients with OSA comorbid HTN compatients with OSA comorbid HTN, it may provide a theoretical foundation for clinical diagnosis and treatment of this condition.
This study highlighted noninvasive biomarkers for patients with OSA comorbid HTN. As the first study to find alterations of the salivary microbiome in patients with OSA comorbid HTN, it may provide a theoretical foundation for clinical diagnosis and treatment of this condition.
To examine the association between sleep and weight status across multiple dimensions of sleep (duration, efficiency, quality and timing) and assess the cumulative influence of these dimensions on the overall sleep-obesity association.
Cross-sectional data from 2253 students aged 8.8 to 13.5 years participating in two monitoring studies across regional Victoria was analyzed. Students were invited to have measures of height and weight taken and to complete a self-report electronic questionnaire on demographic characteristics and health behaviors. Logistic regression models were used to assess association between sleep dimensions and BMI z-scores.
Beyond sleep duration, poor perceived sleep quality, delayed sleep initiation, later bed times and sleep-wake timing, all significantly increased the odds of overweight/obesity (OR 1.47, 95% CI 1.07-2.01; OR 1.25, 95% CI 1.02-1.55; and OR 1.70. 95% CI 1.28-2.28, respectively). Additionally, a cumulative effect of having multiple poorly scored sleep dimensions was found, where four or more poorly scored sleep dimensions more than doubled the odds of overweight/obesity among children (OR 2.25, 95% CI 1.41-3.58).
This study highlights the importance of measuring and considering multiple dimensions of sleep, along with the individual and additive influence of the sleep dimension on the sleep-obesity nexus.
This study highlights the importance of measuring and considering multiple dimensions of sleep, along with the individual and additive influence of the sleep dimension on the sleep-obesity nexus.
Coronary heart disease (CHD) is the leading cause of morbidity and mortality globally. BI-3231 This study aimed to examine the preliminary effect of a nurse-led support programme using a mobile application versus nursing telephone advice on patients at risk of CHD living in the community.
A prospective randomized controlled trial was adopted. Sixty eligible CHD participants were randomized into the app group (App) or the nursing telephone advice (NTA) group to support their own health care and exercise. Data were collected at baseline (T0), 1 month (T1), and 3 months (T2). Outcomes were total amount of exercise, self-efficacy of chronic disease management, total time of exercise, blood pressure, and lipid concentrations. Data were analyzed using the generalized estimating equation models.
Ninety-two individuals were screened for eligibility and 60 were randomized into the app group (n = 30) or NTA group (n = 30). The mean age of the participants was 60.92. The total attrition rate at T2 was 1.66%. The app group showed a moderate effect (Cohen's d =0.43) in significant increase in exercise amount, and reduction of lipid concentration (total cholesterol d=-0.43, triglyceride d=-0.39) respectively. Other outcomes showed improvement trend but non-significant between group.
The CHD app is effective to motivate CHD patients for maintaining exercise amount which will be beneficial to their lipid control.
The CHD app is effective to motivate CHD patients for maintaining exercise amount which will be beneficial to their lipid control.
This study aims to investigate the effect of mindfulness on flow at the organizational and individual levels. Based on perseverative cognition theory, we introduced work-related rumination (affective rumination and problem-solving pondering) as the transmitter in these processes.
This study conducted a three-wave longitudinal survey. The data of 458 employees and 114 leaders were collected from three software parks in China. Multilevel structural equation modeling and the Markov Chain Monte Carlo method were adopted to test all hypotheses.
Employee mindfulness and leader mindfulness help reduce affective rumination by employees and increase their problem-solving pondering and flow experiences. Affective rumination and problem-solving pondering partially mediate the relationship between leader and employee mindfulness and flow. Leader mindfulness moderates the effects of employees' mindfulness on their affective rumination and problem-solving pondering.
Our findings contribute to the current literature on mindfulness, work-related rumination and flow experience and extend the understanding of the effect boundary of mindfulness. This study also helps guide organizations to better design and carry out mindfulness and flow interventions.
Our findings contribute to the current literature on mindfulness, work-related rumination and flow experience and extend the understanding of the effect boundary of mindfulness. This study also helps guide organizations to better design and carry out mindfulness and flow interventions.
University life is a critical time when students start thinking about their careers in the future. Emotions and confidence are important factors in the career decision-making process. This process of choosing a specific direction towards a career often opens students to many uncertain situations, leading them to stress and anxiety. Emotional intelligence and generalized self-efficacy facilitate students in effective career decision-making by coping with difficulties during academia. The present study aimed to find the impact of emotional intelligence (EI) on career decision-making (CDM) and generalized self-efficacy (GSE) among university students in China.
The study included 310 undergraduate students from different universities of China. A cross-sectional research design was used and a convenient sampling technique was utilized. For the present study, Wong and Law emotional intelligence, generalized self-efficacy, and career decision-making difficulties scales were utilized.
Findings of the study show that there is a significant relationship between EI, GSE, and career decision-making difficulties. Results revealed a significant positive relationship of GSE with emotional intelligence. GSE has a significant negative relationship with career decision-making difficulties. Moreover, EI has a significant negative relationship with career decision-making difficulties.
The study will help students to utilize emotional intelligence skills during academic and vocational life. For future research, qualitative studies would be conducted to better explore the underlying causes behind career decision-making difficulties.
The study will help students to utilize emotional intelligence skills during academic and vocational life. For future research, qualitative studies would be conducted to better explore the underlying causes behind career decision-making difficulties.
