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To test medical students' perceptions of the impact of artificial intelligence (AI) on radiology and the influence of these perceptions on their choice of radiology as a lifetime career.

A cross-sectional multicenter survey of medical students in Saudi Arabia was conducted in April 2019.

Of the 476 respondents, 34 considered radiology their first specialty choice, 26 considered it their second choice, and 65 considered it their third choice. Only 31% believed that AI would replace radiologists in their lifetime, while 44.8% believed that AI would minimize the number of radiologists needed in the future. Approximately 50% believed they had a good understanding of AI; however, when knowledge of AI was tested using five questions, on average, only 22% of the questions were answered correctly. Among the respondents who ranked radiology as their first choice, 58.8% were anxious about the uncertain impact of AI on radiology. The number of respondents who ranked radiology as one of their top three choices increased by 14 when AI was not a consideration. Radiology conferences and the opinions of radiologists had the most influence on the respondents' preferences for radiology.

The worry that AI might displace radiologists in the future had a negative influence on medical students' consideration of radiology as a career. Academic radiologists are encouraged to educate their students about AI and its potential impact when students are considering radiology as a lifetime career choice.

Rapid advances of AI in radiology will certainly impact the specialty, the concern of AI impact on radiology had negative influence in our participants and investing in AI education and is highly recommended.

Rapid advances of AI in radiology will certainly impact the specialty, the concern of AI impact on radiology had negative influence in our participants and investing in AI education and is highly recommended.

To compare the estimated radiation dose of 50% reduced iodine contrast medium (halfCM) for virtual monochromatic images (VMIs) with that of standard CM (stdCM) with a 120 kVp imaging protocol for contrast-enhanced CT (CECT).

We enrolled 30 adults with renal dysfunction who underwent abdominal CT with halfCM for spectral CT. As controls, 30 matched patients without renal dysfunction using stdCM were also enrolled. CT images were reconstructed with the VMIs at 55 keV with halfCM and 120 kVp images with stdCM and halfCM. The Monte-Carlo simulation tool was used to simulate the radiation dose. The organ doses were normalized to CTDIvol for the liver, pancreas, spleen, and kidneys and measured between halfCM and stdCM protocols.

For the arterial phase, the mean organ doses normalized to CTDIvol for stdCM and halfCM were 1.22 and 1.29 for the liver, 1.50 and 1.35 for the spleen, 1.75 and 1.51 for the pancreas, and 1.89 and 1.53 for the kidneys. As compared with non-enhanced CT, the average increase in the organ dose was significantly lower for halfCM (13.8% ± 14.3 and 26.7% ± 16.7) than for stdCM (31.0% ± 14.3 and 38.5% ± 14.8) during the hepatic arterial and portal venous phases (

< 0.01).

As compared with stdCM with the 120 kVp imaging protocol, a 50% reduction in CM with VMIs with the 55 keV protocol allowed for a substantial reduction of the average organ dose of iodine CM while maintaining the iodine CT number for CECT.

This study provides that the halfCM protocol for abdominal CT with a dual-layer-dual-energy CT can significantly reduce the increase in the average organ dose for non-enhanced CT as compared with the standard CM protocol.

This study provides that the halfCM protocol for abdominal CT with a dual-layer-dual-energy CT can significantly reduce the increase in the average organ dose for non-enhanced CT as compared with the standard CM protocol.

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating condition carrying substantial psychosocial burden. Psychological treatment for IC/BPS is little studied, and there are barriers to its use in clinical management. Whether psychological treatments benefit patients with IC/BPS is unclear and we do not know if such treatments would meet patient needs.

Incorporating patient-reported needs and acknowledging diversity in pain experiences can inform patient-centered interventions for IC/BPS. This project characterized the experience of living with IC/BPS and patient perceptions of needs in its treatment, with the goal of informing patient-centered treatment for IC/BPS.

Using both quantitative and qualitative methods, 27 females with IC/BPS participated in a focus group and completed validated self-report assessments evaluating urinary symptoms, pain, and emotional functioning. Focus groups were audio recorded and transcribed, then coded and analyzed using an iterative inductive/deductive a pain management, emotion regulation, communications skills, along with sexual dysfunction and intimacy fears.A real-world setting study of familial hypercholesterolemia (FH) patients who received Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in a specialized referral center in Mexico City. Ten patients between the ages of 18 and 70 years, with a diagnosis of FH according to Dutch Lipid Clinic Network (DLCN) criteria, with failure to achieve their Low-density lipoprotein Cholesterol (LDL-C) goals, and with standard therapy between 2016 and 2017 enrolled in a simple randomization in which a group of 5 participants received alirocumab (75 mg every 2 weeks) and the remaining 5 patients received evolocumab (140 mg every 2 weeks). Comparative analysis was made, analyzing the means of LDL at baseline at 4, 6, and 12 weeks. The evolocumab group had an average initial LDL-C of 277 mg/dL, which, after 12 weeks of treatment, was significantly reduced to 116 mg/dL; P = 0.04 (95% confidence interval [CI] 11.5-310.9). Epigenetic inhibitor nmr The alirocumab group with a mean initial LDL-C of 229 mg/dL showed a reduction of LDL-C levels at 12 weeks of treatment to 80 mg/dL; P = 0.008 (95% CI 63.8-233.7). In conclusion, PCSK9 inhibitors are an excellent treatment option in patients with FH who do not reach their LDL-C goals with standard therapy or due to intolerance to the standard therapy. There is no difference in the lipid-lowering effect between both PSCK9 inhibitors.

Controversy surrounds the extent and intensity of the management of American Thyroid Association (ATA) intermediate- and low-risk patients with differentiated thyroid cancer (DTC). Understanding the natural history and factors that predict outcome is important for properly tailoring the management of these patients.

This work aims to study the natural course and predictive factors of incomplete response to therapy in low- and intermediate-risk DTC.

We studied a cohort of 506 consecutive patients [418 women (82.6%) and 88 men (17.4%)] with low and intermediate risk with a median age of 35 years (interquartile range [IQR], 27-46 years). We analyzed the natural course and the predictive factors of biochemically or structurally incomplete response.

Of 506 patients studied, 297 (58.7%) patients were in the low-risk group and 209 (41.3%) were in the intermediate-risk group. Over a median follow-up of 102 months (IQR, 66-130 months), 458 (90.5%) patients achieved an excellent response, 17 (3.4%) had a biocheowed up more actively than younger patients and those without LNM.The conclusion of Panayiotopoulos et al. that glucocorticoid resistance accounted for 57% to 67% of their premature adrenarche and polycystic ovary syndrome cases cannot be accepted from the data presented. This is because proper validation of their method for determining glucocorticoid sensitivity is not presented. Furthermore, the method seems insensitive to physiologic glucocorticoid concentrations.Strongly long-range interacting quantum systems-those with interactions decaying as a power law 1/r α in the distance r on a D-dimensional lattice for α ⩽ D-have received significant interest in recent years. They are present in leading experimental platforms for quantum computation and simulation, as well as in theoretical models of quantum-information scrambling and fast entanglement creation. Since no notion of locality is expected in such systems, a general understanding of their dynamics is lacking. In a step towards rectifying this problem, we prove two Lieb-Robinson-type bounds that constrain the time for signaling and scrambling in strongly long-range interacting systems, for which no tight bounds were previously known. Our first bound applies to systems mappable to free-particle Hamiltonians with long-range hopping, and is saturable for α ⩽ D/2. Our second bound pertains to generic long-range interacting spin Hamiltonians and gives a tight lower bound for the signaling time to extensive subsets of the system for all α less then D. This many-site signaling time lower bounds the scrambling time in strongly long-range interacting systems.Tensor networks are a powerful tool for many-body ground states with limited entanglement. These methods can nonetheless fail for certain time-dependent processes-such as quantum transport or quenches-where entanglement growth is linear in time. Matrix-product-state decompositions of the resulting out-of-equilibrium states require a bond dimension that grows exponentially, imposing a hard limit on simulation timescales. However, in the case of transport, if the reservoir modes of a closed system are arranged according to their scattering structure, the entanglement growth can be made logarithmic. Here, we apply this ansatz to open systems via extended reservoirs that have explicit relaxation. This enables transport calculations that can access steady states, time dynamics and noise, and periodic driving (e.g., Floquet states). We demonstrate the approach by calculating the transport characteristics of an open, interacting system. These results open a path to scalable and numerically systematic many-body transport calculations with tensor networks.Accessory renal arteries (ARAs) are embryonic remnants found in more than one-third of patients and occurring bilaterally in 10% of the population. Very few reports have documented such vessels arising near or at the level of the aortic bifurcation. Furthermore, the presence of ARAs has yet to be described in the context of atherosclerotic disease. Here, we present a unique case of large bilateral ARAs originating above the aortic bifurcation concurrent with symptomatic aortoiliac atherosclerotic disease. We highlight the embryologic and clinical significance of these vessels as well as discuss their potential role in accelerating atherosclerotic disease processes.Infrapopliteal artery aneurysms are rare, and tibioperoneal trunk aneurysms are even rarer. We herein report an unusual case of large tibioperoneal trunk pseudoaneurysm. The patient underwent successful endovascular exclusion of the pseudoaneurysm by coil embolization with stent assistance. The clinical features and management of tibioperoneal trunk aneurysms are also discussed in this article.Adventitial cystic disease of the venous system is an extremely rare condition. Forty-five cases have been described in the literature during the last 70 years, but they may not be representative of the real incidence of this pathologic process. We report a case of an adventitial cyst compressing the right external iliac vein and presenting with edema of the ipsilateral leg. Ultrasound imaging and computed tomography angiography showed the typical features of cystic disease and venous stenosis. Cyst excision was performed with a double surgical access. No perioperative complications were reported. There was no recurrence at 4-year follow-up.

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