Wagnerashley2847

INTRODUCTION Approximately 350 million people have depression. The presence of arterial hypertension is a major risk factor for mental health. However, several studies on the association between arterial hypertension and depressive symptoms present controversial evidence. We aimed at identifying whether there is an association between arterial hypertension and depressive symptoms, taking into account the time since hypertension diagnosis. METHODS A secondary analysis of the Demographic and Health Survey in Peru (2014-2016) was conducted. The outcome was depressive symptoms, while hypertension and time since hypertension diagnosis were the exposure of interest. Poisson regression models were created, reporting prevalence ratios (PR) and 95% confidence intervals (95% CI). this website RESULTS Data from 87 253 participants were analyzed. A total of 2633 (3.0%; 95% CI 2.8%-3.2%) individuals had depressive symptoms, whereas hypertension was present in 15 681 (19.6%; 95% CI 19.1%-20.1%) subjects. In the multivariable model, people with less than a year since diagnosis were more than twice as likely to have depressive symptoms (PR = 2.08, 95% CI 1.65-2.63) compared to the group of people without hypertension. This probability decreased for individuals with 1 to 4 years since diagnosis (PR = 1.42, 95% CI 1.13-1.80), and for people with ≥5 years since diagnosis (PR = 1.29, 95% CI 1.01-1.64). CONCLUSIONS There is an association between hypertension and depressive symptoms, but this varies depending on time since diagnosis. Thus, individuals with less then 1 year since diagnosis had the highest probability of having depressive symptoms; after that, that probability decreased as the time since diagnosis increased. © 2020 John Wiley & Sons Australia, Ltd.Five traditional medicinal food from Tibetan plateau including Nitraria tangutorum B. (NT), Hippophae rhamnoides L. (HR), Lycium ruthenicum M. (LR), Lycii fructus (LF) and Rubuscor corchorifolius L. f. (RC) are rich in phenolic compounds. However, the detailed studies about the phenolic compounds remain scarce. Therefore, we established a rapid method for the simultaneous identification and quantification of the phenolic compounds from berries via Ultra Performance Liquid Chromatography-Quadruple-Orbitrap MS system (UPLC-Q-Orbitrap MS). This method was verified from many aspects including detection limit, quantification limit, precision, repeatability, stability, average recovery rate and recovery range, and then was used to analyze the phenolic compounds in these five species of berries. Finally, a total of 21 phenolic compounds were directly identified by comparing the retention time and exact mass. Of which, 14 compounds were identified by us for the first time in berries from Tibetan plateau, including one flavonoid aglycone (myricetin), 11 phenolic acids (gallic acid, protocatechuate, chlorogenic acid, vanillic acid, coffeic acid, syringate, p-coumaric acid, ferulic acid, O-hydroxybenzene acetic acid and ellagic acid), one flavanol (catechin) and one dihydrochalcone flavonoid (phloretin). Quantitative results showed that rutin, myricetin, quercetin and kaempferol were the main flavonoids. Moreover, a variety of phenolic acid compounds were also detected in most of the berries from Tibetan plateau. Among these compounds, the contents of protocatechuate and chlorogenic acid were high, and high levels of catechin and phloretin were also detected in these plateau berries. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Due to the high abundance and gravimetric capacity (1165.78 mAh g-1) of pure sodium, it is considered as promising candidate for the anode of next-generation batteries. However, one major challenge needs to be solved before commercializing the sodium metal anode the growth of dendrites during metal plating. One possibility to address this challenge is to use additives in the electrolyte in order to form a protective solid electrolyte interphase on the anode surface. In this work, we introduce a diamondoid-based additive, which is incorporated into the anode to target this problem. Combining operando and ex situ experiments (electrochemical impedance spectroscopy, optical characterization and cycling experiments), we show that molecular diamondoids are incorporated into the anode during cycling and successfully mitigate the growth of dendrites. Furthermore, we demonstrate the positive effect of the additive on the operation of sodium-oxygen batteries by means of increased energy density. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Recent efforts to improve the capacitances of Kraft lignin (KL) in supercapacitors have mainly focused on screening KL substrates, which could either compensate the poor conductivity of KL or directly contribute to the capacitance. However, increasing the pseudocapacitance contributed by KL itself, through hydroquinone/quinone redox cycles, remains a challenge, owing to the roughly fixed content of hydroquinone species in natural KL. In this study, the capacitance of KL is greatly improved by using a functional-group modification strategy in which methoxy groups in KL are selectively converted into phenolic hydroxy groups, which facilitate the formation of additional hydroquinone moieties and thus lead to higher pseudocapacitances. The oxidized KL materials show up to 25.6 % enhancement of the phenolic hydroxy content in comparison to raw KL, which results in 21.9 % capacitance improvement from 322 to 390 F g-1 at 0.5 A g-1 in an acidic system. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.RATIONALE Oxidative stress is an imbalance between reactive free radical oxygen species and antioxidant defenses. The consequences can lead to numerous pathologies. Regulating oxidative stress is the complex interplay between antioxidant recycling and thiol-containing regulatory proteins. Understanding these regulatory mechanisms is important to prevent onset of oxidative stress. The aim of this study was to investigate S-thiol protein chemistry associated with oxidized vitamin C (dehydroascorbate, DHA), homocysteine (HcySH) and glutathione (GSH) using mass spectrometry. METHODS Glutaredoxin-1 (Grx-1) was incubated with DHA, with and without GSH and HcySH. Disulfide formation was followed by ESI mass spectrometry (ESIMS) of intact protein, and by LC/ESIMS/MS of peptides from protein tryptic digestions. The mechanism of DHA-mediated S-thiolation was investigated using two synthetic peptides; AcFHACAAK and AcFHACE. Three proteins i.e. human hemoglobin (HHb)), recombinant peroxiredoxin 2 (Prdx2), and Grx-1 were S-homocysteinylated followed by S-transthiolyation with GSH and investigated by ESIMS and ESIMS/MS.