Keeneboisen9921

Clinicians have diverse concerns about the implications of e-consults for communication and relationships. Our findings may inform efforts to expand and improve the use of e-consults in diverse health care settings.

Clinicians have diverse concerns about the implications of e-consults for communication and relationships. Our findings may inform efforts to expand and improve the use of e-consults in diverse health care settings.In this work, the multilevel resistive random access memories (RRAMs) have been achieved by using the structure of Pt/MoO3/Hf/MoO3/Pt with four stable resistance states. The devices show good retention property of each state (>104s) and large memory window (>104). The simulation and experimental study reveal that the resistive switching mechanism is ascribed to combination of the conductive filament in the stack of MoO3/Hf next to the top electrode and redox reaction at the interface of Hf/MoO3next to bottom electrode. The fitting results of current-voltage characteristics under low sweep voltage indicate that the conduction of HRSs is dominated by the Poole-Frenkel emission and that of LRS is governed by the Ohmic conduction. Based on the RRAM, the tunable high-pass filter (HPF) with configurable filtering characteristics has been realized. The gain-frequency characteristics of the programmable HPF show that the filter has high resolution and wide programming range, demonstrating the viability of the multilevel RRAMs for future spiking neural network and shrinking the programmable filters with low power consumption.In this work, we prepared NiCo alloy/C with rhombic dodecahedron structure and superior microwave absorption performance by using ZIF-67 as the raw material. The rhombic dodecahedron NiCo alloy/C was with rough particles on the surface was photographed by field emission scanning electron microscopy. By adjusting the doping amount of Ni and the temperature of pyrolysis, improved the impedance matching of NiCo alloy/C. Specifically, NiCo alloy/C exhibits a minimum reflection loss of -65.48 dB at 13.48 GHz, while the thickness is 1.63 mm. Defects introduced in the Ni doping process and the special rhombic dodecahedral structure can cause multiple loss mechanisms. Therefore, this NiCo alloy/C composite has the potential to be a potential microwave absorber material with lightweight and high microwave absorption properties.Young's modulus of tapered mixed composition (zinc-blende with a high density of twins and wurtzite with a high density of stacking faults) gallium phosphide (GaP) nanowires (NWs) was investigated by atomic force microscopy. Experimental measurements were performed by obtaining bending profiles of as-grown inclined GaP NWs deformed by applying a constant force to a series of NW surface locations at various distances from the NW/substrate interface. Numerical modeling of experimental data on bending profiles was done by applying Euler-Bernoulli beam theory. Measurements of the nano-local stiffness at different distances from the NW/substrate interface revealed NWs with a non-ideal mechanical fixation at the NW/substrate interface. Analysis of the NWs with ideally fixed base resulted in experimentally measured Young's modulus of 155 ± 20 GPa for ZB NWs, and 157 ± 20 GPa for WZ NWs, respectively, which are in consistence with a theoretically predicted bulk value of 167 GPa. JQ1 supplier Thus, impacts of the crystal structure (WZ/ZB) and crystal defects on Young's modulus of GaP NWs were found to be negligible.A novel method based on the fundamental measure theory is developed to calculate the solvation force and adsorption isotherm of a Lennard-Jones fluid mixture in complex geometries. Fast Fourier transform and 3D-voxel discretization are used for accurately computing the confined fluid densities in a closed pore of arbitrary geometry. Given the fluid densities, the solvation force distribution at the solid surface can be calculated using a new formulation from either mechanical or thermodynamic approach. Understanding the solvation force behavior, which depends on many factors such as pore geometry, confined density distribution, molecule size, is very important to analyze the pore deformation from a poromechanical point of view. Special attention in the numerical simulations is given to the adsorption problem of CH4and CO2gas mixture in ellipsoidal pore.One-step evaporative jamming of colloidal silica particles in contact-free spray droplets resulted in well-defined powder micro-granules with interstitial nanopores. link2 This paper reports the anomalous freezing behaviour of confined water in the microspheres synthesized using spray drying. It has been revealed that the freezing point of water in these microspheres gets significantly lowered (∼-45 °C) owing to the confinement effect. Thermoporometry results are corroborated with the structural details obtained using complementary techniques of gas adsorption measurements and small-angle x-ray scattering.Weak-coupling phenomena of the two-dimensional Hubbard model is gaining momentum as a new interesting research field due to its extraordinarily rich behavior as a function of the carrier density and model parameters. Salmhofer (1998Commun.Math.Phys.194249; 2001Phys.Rev.Lett.87187004) developed a new renormalization-group method for interacting Fermi systems and Metzner (2000Phys.Rev. B617364; 2000Phys.Rev.Lett.855162) implemented this renormalization group analysis of the two-dimensional Hubbard model. In this work, we demonstrate the spin-wave dependent electronic structure and susceptibility behavior of model graphene-phosphorene van der Waals heterostructure in the framework of renormalization group approach. We implement singlet vertex response function for the weakly interacting van der Waals Fermi system with nearest-neighbor hopping amplitudes. This analytical approach is further extended for spin-wave dependent susceptibility behavior. We present the resulting compressibility and phase diagram in the vicinity of half-filling, and also results for the density dependence of the critical energy scale.Objective.In this study, we conducted a comparative analysis of deep convolutional neural network (CNN) models in predicting obstructive sleep apnea (OSA) using electrocardiograms. Unlike other studies in the literature, this study automatically extracts time-frequency features by using CNNs instead of manual feature extraction from ECG recordings.Approach.The proposed model generates scalogram and spectrogram representations by transforming preprocessed 30 s ECG segments from time domain to the frequency domain using continuous wavelet transform and short time Fourier transform, respectively. We examined AlexNet, GoogleNet and ResNet18 models in predicting OSA events. The effect of transfer learning on success is also investigated. Based on the observed results, we proposed a new model that is found more effective in estimation. In total, 152 ECG recordings were included in the study for training and evaluation of the models.Main results.The prediction using scalograms immediately 30 s before potential OSA onsets gave the best performance with 82.30% accuracy, 83.22% sensitivity, 82.27% specificity and 82.95% positive predictive value. The prediction using spectrograms also achieved up to 80.13% accuracy and 81.99% sensitivity on prediction. Per-recording classification suggested considerable results with 91.93% accuracy for prediction of OSA events.Significance.Time-frequency deep features of scalograms and spectrograms of ECG segments prior to OSA events provided reliable information about the possible events in the future. The proposed CNN model can be used as a good indicator to accurately predict OSA events using ECG recordings.Cell alignment plays an essential role in cytoskeleton reorganization, extracellular matrix remodeling, and biomechanical properties regulation of tissues such as vascular tissues, cardiac muscles, and tendons. Based on the natural-oriented features of cells in native tissues, various biomimetic scaffolds have been reported with the introduction of well-arranged ultrafine fibers to induce cell alignment. However, it is still a challenge to fabricate scaffolds with suitable mechanical properties, biomimetic microenvironment, and ability to promote cell alignment. In this paper, we propose an integrated 3D printing system to fabricate multi-scale hierarchical scaffolds combined with meso-, micro-, and nano-fibrous filaments, in which the meso-, micro-, and nano-fibers fabricated via fused deposition modeling, melt electrospining writing, and solution electrospining can provide structural support, promote cell alignment, and create a biomimetic microenvironment to facilitate cell function, respectively. The plasma surface modification was performed improve the surface wettability of the scaffolds by measuring the contact angle. link3 The obtainedin vitrobiological results validate the ability of multi-scale hierarchical scaffolds to enhance cell adhesion and proliferation, and promote cell alignment with the guidance of the aligned microfibers produced via melt electrospining writing in hierarchical scaffolds.Nucleic acid-based gene therapy has recently made important progress toward clinical implementation, and holds tremendous promise for the treatment of some life-threatening diseases, such as cancer and inflammation. However, the on-demand delivery of nucleic acid therapeutics in target cells remains highly challenging. The development of delivery systems responsive to specific pathological cues of diseases is expected to offer promising alternatives for overcoming this problem. Among them, the reactive oxygen species (ROS)-responsive delivery systems, which in response to elevated ROS in cancer cells or activated inflammatory cells, can deliver nucleic acid therapeutics on-demand via ROS-induced structural and assembly behavior changes, constitute a promising approach for cancer and anti-inflammation therapies. In this short review, we briefly introduce the ROS-responsive chemical structures, ROS-induced release mechanisms and some representative examples to highlight the current progress in constructing ROS-responsive delivery systems. We aim to provide new insights into the rational design of on-demand gene delivery vectors.In this study, we offer new insights into the contrasting effects of electrospun fiber orientation on microglial polarization under normoxia and hypoxia, and establish for the first time, the intrinsically protective roles of electrospun meshes against hypoxia-induced microglial responses. First, resting microglia were cultured under normoxia on poly(caprolactone) fibers possessing two distinctly different fiber orientations. Matrix-guided differences in cell shape/orientation and differentially expressed Rho GTPases (RhoA, Rac1, Cdc42) were well-correlated with the randomly oriented fibers inducing a pro-inflammatory phenotype and the aligned fibers sustaining a resting phenotype. Upon subsequent hypoxia induction, both sets of meshes offered protection from hypoxia-induced damage by promoting a radical phenotypic switch and beneficially altering the M2/M1 ratio to different extents. Compared to 2D hypoxic controls, meshes significantly suppressed the expression of pro-inflammatory markers (IL-6, TNF-α) and induced drastically higher expression of anti-inflammatory (IL-4, IL-10, VEGF-189) and neuroprotective (Nrf-2) markers.