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50), chest expansion (CE) (r=-.40), finger-to-floor (FFD) (r=.55), number of swollen joints (r=.69), and number of enthesitis (r=.68). The divergent validity demonstrated weak correlations between BASDAI and OWD (r=.43), MSD (r=.34), CE (r=-.44), FFD (r=.47). The divergent validity of BASFI could not be assessed due to lack of a suitable comparing parameter. The instruments revealed acceptable internal consistency as Cronbach's alpha was 0.86 for BASDAI and 0.93 for BASFI. A 7-day test-retest reliability measured by the intraclass correlation coefficient were 0.80 (CI at 95% = 0.58-0.90) for BASDAI and 0.83 (CI at 95% = 95% 0.64-0.92) for BASFI respectively.

Bangla version of BASDAI and BASFI may be useful in disease activity and functional ability assessment in AS patients.

Bangla version of BASDAI and BASFI may be useful in disease activity and functional ability assessment in AS patients.

Food insecurity (a lack of stable access to nutritious food) is reliably associated with poor diet, malnutrition, and obesity; however, the underlying mechanisms are unclear. In this study, the hypothesis that these relations are explained by higher levels of distress, which are due to the experience of food insecurity, and unhealthy coping behaviors (eating high-calorie foods, drinking alcohol) was tested.

Adults from the United Kingdom (N = 604), who were recruited online and at food banks, completed questionnaire measures of household food insecurity, physical stress, psychological distress, eating to cope, drinking to cope, diet quality, and self-reported height and weight to calculate BMI.

Structural equation modeling was used to test the hypothesized relationships, including a multilevel structural model controlling for the effect of income. As predicted, food insecurity was indirectly associated with higher BMI via greater distress and eating to cope. Food insecurity was directly associated with poorer diet quality, but this relationship was not explained by distress and eating to cope CONCLUSIONS Our data provide novel insight into the psychological experience of being food-insecure and how maladaptive coping mechanisms might play some role in the association between food insecurity, diet, and obesity.

Structural equation modeling was used to test the hypothesized relationships, including a multilevel structural model controlling for the effect of income. As predicted, food insecurity was indirectly associated with higher BMI via greater distress and eating to cope. Food insecurity was directly associated with poorer diet quality, but this relationship was not explained by distress and eating to cope CONCLUSIONS Our data provide novel insight into the psychological experience of being food-insecure and how maladaptive coping mechanisms might play some role in the association between food insecurity, diet, and obesity.

Up to 3% of methotrexate (MTX)-treated rheumatoid arthritis (RA) patients may develop liver fibrosis or cirrhosis, requiring effective screening algorithms.

To assess the utility of non-invasive liver fibrosis assessment in RA patients on MTX.

56 patients were recruited from rheumatology outpatient clinics in a public tertiary centre from July 2017 to October 2018. Clinical data was collected. Screening for hepatic fibrosis was performed utilising transient elastography (TE), aminoaspartate transaminase to platelet ratio index (APRI), Hepascore, and Fibrosis-4 index (FIB-4). Those with suspected significant liver fibrosis based on these screening tests were assessed by a hepatologist.

27 patients were suspected to have liver fibrosis on screening, including 10/56 (18%) by TE, 20/56 (36%) by Hepascore, 2/56 by APRI (4%) and 1/56 by FIB-4 (2%). Of these 27 patients, 11 were reviewed by a hepatologist and 1 diagnosed with significant liver fibrosis. TE, but not APRI, Hepascore or FIB-4, was found to have 100% sensitivity and 84% specificity (p=0.029) for hepatologist-diagnosed liver fibrosis.

Liver fibrosis develops in a minority of MTX-treated RA patients. This study suggests that TE is a more sensitive screening test than APRI, FIB-4 or Hepascore in the identification of people with RA at risk of hepatic fibrosis. This article is protected by copyright. All rights reserved.

Liver fibrosis develops in a minority of MTX-treated RA patients. This study suggests that TE is a more sensitive screening test than APRI, FIB-4 or Hepascore in the identification of people with RA at risk of hepatic fibrosis. Sodium butyrate inhibitor This article is protected by copyright. All rights reserved.

Deficits in social cognition can occur in multiple sclerosis (MS) patients, and different methods are utilized for its assessment. The aim of this study was to compare two tests of social cognition in a cohort of multiple sclerosis patients with respect to other clinical variables. Additionally, the impact of social cognition on quality of life was investigated.

In total, 50 patients were included in the study. Two tests of social cognition, emotion recognition and theory of mind, were performed and controlled for disease disability, depression, fatigue, and cognition in a multiple linear regression. Assessment of quality of life was also conducted.

Accuracy on emotion recognition was better compared to theory of mind (86.5±9.5% and 63.6±10.1%, respectively). Cognition was associated with both social cognition tasks, accounting for more variance in the emotion recognition task. Quality of life was not related to social cognition.

Studies on social cognition in MS have to keep in mind the higher degree of cognitive influence of emotion recognition compared to theory of mind.

Studies on social cognition in MS have to keep in mind the higher degree of cognitive influence of emotion recognition compared to theory of mind.

To evaluate the effectiveness of a combined patient empowerment program (PEP) and cognitive training (CT) program on improving glycemic control among older subjects with diabetes and cognitive impairment.

A prospective single blinded, randomized controlled study was carried out in 139 older patients with diabetes aged ≥65 years with memory complaints and recent glycosylated hemoglobin level of 7-9%. They were randomly assigned to either undergo once-weekly PEP combined with CT for 10 weeks (intervention group, N = 73) or receive no intervention (control group, N = 66). All participants were followed up at months 4 and 12 to examine the immediate and long-term effects on glycemic control, cognition, mood and compliance to drug and diabetes self-management.

The intervention did not significantly reduce glycosylated hemoglobin. The intervention group showed significant progressive improvement in memory over 1 year and executive function improved significantly at month 12. There was no significant change in diabetes self-management activities with the intervention.

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