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This study evaluated moisture loss, oil gain and porosity when frying pieces of yam (Dioscorea rotundata). The parallelepiped-shaped samples, approximately 1 × 1 × 4 cm, were subjected to frying temperatures of 145, 165 and 185 °C for 50, 150, 300, 450, or 600 s. Fick's law was used to determine the diffusion coefficient from the experiment data for the varieties 153 traditional Espino and 125 Brazilian Espino. The moisture loss in 153 traditional Espino was greater than in 125 Brazilian Espino. The diffusion coefficient and the activation energy were determined for both varieties, which were higher in the 153 traditional Espino variety. The porosity was expressed as a percentage and was also higher in the 153 traditional Espino variety.With a huge amount of information being stored as structured data, there is an increasing need for retrieving exact answers to questions from tables. Answering natural language questions on structured data usually involves semantic parsing of query to a machine understandable format which is then used to retrieve information from the database. Training semantic parsers for domain specific tasks is a tedious job and does not guarantee accurate results. In this paper, we used conversational analytics tool to create the user interface and to get the required entities and intents from the query thus avoiding the traditional semantic parsing approach. We then make use of Knowledge Graph for querying in structured data domain. Knowledge graphs can be easily leveraged for question answering systems, to use them as the database. We extract appropriate answers for different types of queries which have been illustrated in the Results section.

So far, various etiologies have been stated for Intra-uterine growth restriction (IUGR) with a wide variety of pathways involved in their pathogenesis. Among these pathways, impaired angiogenesis, inflammation, and oxidative stress are among the most important ones. Curcumin has raised notable attention due to its anti-inflammatory and antioxidant activity in different

studies and clinical trials. Sotrastaurin The present study aimed to investigate the possible potentials of Curcumin for pregnancies complicated by IUGR through different physiological mechanisms.

A narrative review study was conducted (Iran; 2020). The implemented Mesh-based keywords were "Curcumin" OR "Turmeric" AND "Therapeutic effect" AND "Side effect" OR "Adverse effect" OR "Teratogenic effect" OR "Teratogenicity" AND "Pregnancy" AND "Intra-uterine growth restriction" OR "Intra-uterine growth retardation" AND "Inflammation" AND "Oxidative stress" AND "Angiogenesis". Cochrane Library, PubMed, Up to date, Scopus, and Google Scholar databases were used as academic search engines.

Reviewing the included studies showed the dual effects of curcumin on angiogenesis depend on the type of angiogenesis physiological or pathological. Interestingly, the present study evaluated the current knowledge on the effects of curcumin on IUGR demonstrating acceptable potentials. Also, we tried to gather studies that had evaluated the safety of curcumin during pregnancy.

Gathering all the data, it seems curcumin could be an acceptable candidate for future animal and human studies on IUGR.

Gathering all the data, it seems curcumin could be an acceptable candidate for future animal and human studies on IUGR.Vehicle routing problem is a widely researched combinatorial optimization problem. We developed a hybrid of three strategies-a modified ant system, a sweep algorithm, and a path relinking-for solving a capacitated vehicle routing optimization problem, a vehicle routing problem with a capacity constraint. A sweep algorithm was used to generate initial solutions and assign customers to vehicles, followed by a modified ant system to generate new generations of good solutions. Path relinking was used for building a better solution (candidate) from a pair of guiding and initial solutions. Finally, a local search method-swap, insert, reverse and greedy search operations-was used to prevent solutions from getting trapped in a local minimum. Performance of the proposed algorithm was evaluated on three datasets from CVRPLIB. Our proposed method was at least competitive to state-of-the-art algorithms in terms of the total route lengths. It even surpassed the best-known solution in the P-n55-k8 instance. Our findings can lower the transportation cost by reducing the travelling distance and efficiently utilizing the vehicle capacity.In this paper, we attempt to investigate the efficiency of emerging stock markets by considering the advent of dramatic country-specific events. In other words, we analyze and rank the weak-form efficiency levels of emerging stock markets based on a multi-step approach. Our findings support evidence of multifractality and anti-persistent movements of returns, implying a departure from the weak-form efficiency hypothesis. We also show that the political events adversely affect the efficiency degree of most markets. The empirical results clearly display the dynamic behavior of market efficiency. These findings are in line with the implications of the Adaptive Market Hypothesis.Opuntia ficus-indica L. Mill cladodes are considered to be a source of an abundance of bioactive compounds. To identify a natural product that can be used in the chemoprevention and treatment of cancer, this study was conducted to produce an anticancer agent extracted from in vitro-derived cladodes of prickly pear cactus. Toward this goal, assays of seed germination and micropropagation revealed that the highest seed germination rate was 66% and that the highest shoot number per explant was obtained with benzyl adenine (BA) (2 mg/l) and kinetin (Kin) (1 mg/l) within 2 months, at 22.6. In addition, the maximum length of shoots was obtained with BA (3 mg/l) and Kin (0.5 mg/l), at 7.44 cm. The in vitro-derived cladode extract showed higher total phenolic and kaempferol contents than the in vivo-derived cladode extract (total phenolics 156.5 mg/g and 86 mg/g DW; kaempferol 2.807 mg/g and 1.304 mg/g DW, respectively). These remarkable results reflected the anticancer activity on the viability and proliferation/migration of PC3 prostate and mammary Mcf7-7 cells. In terms of cytotoxicity, the IC50 values on PC3 and Mcf7 cells were 5775.7 and 6311.3 μg/ml, respectively, showing dose-dependent increases. Meanwhile, from in vivo analyses of the plants, the IC50 values were 5927.93 and 6825.6 μg/ml, respectively, again showing dose-dependent increases.The principal context of this study was a combined heat and power plant (CHPP) system, with the aim of conducting the multi-objective optimization (MOO) of an energy, exergy, and economic (3E) analysis. To meet rising energy demands, optimal operational conditions for CHPPs are required. Enhancements to plant equipment and improvements in plant design are critical. CHPP design has its basis in the first law of thermodynamics; the losses from such systems are therefore most accurately determined via exergy analysis. Energy quality can also be assessed using exergy analysis. Consequently, it is possible for the designers of thermodynamic systems to apply the findings to achieve improved efficiencies. The economic aspect of CHPP optimization is also critical because the structure is highly complex. This study therefore makes use of a Henry gas solubility optimization (HGSO) algorithm in a CHPP base case situation to achieve MOO. In this particular CHPP system, the respective enthalpy and exergy efficiencies were increased in the case of the boiler (7.22% and 7.21%), the turbogenerator (4.52% and 6.84%), and the condenser (3.06% and 31.37%). In this study, four scenarios are proposed, whereby the design of a heat exchanger network (HEN) aims to optimize energy savings and economic performance through analysis of the profits generated through electricity and steam production. A payback period of around two to three years was reported, where the cost increase under optimal conditions was found to be 0.3824%. The results demonstrate clearly that the tested techniques may be appropriate in practical scenarios when enhancing CHPP performance in the context of the base case.[This corrects the article DOI 10.1016/j.heliyon.2021.e07823.].[This corrects the article DOI 10.1016/j.heliyon.2021.e07495.].The primary aim of this study was to identify factors influencing natural honey production and marketing constraints in Kafa, Sheka, Bench- Sheko, and West Omo zones which covered 23 woredas and 69 kebeles. Primary and secondary sources of data were utilized for this study. Both qualitative and quantitative data types were employed. Data were collected from 94, 134, 118, and 39 respondents that were selected randomly from Bench- Sheko, Kaffa, Sheka, and West-Omo Zones respectively, based on probability proportional to the sample size. The collected data were analyzed by using descriptive statistics and a multiple linear regression model. The dominant honey production practice in the study area was the use of traditional beehives. The productivity of traditional, transitional, and modern beehives was 9, 16, and 22 kg per hive. Major constraints that affect honey production include lack of modern technology (92.5%), absconding (69.5%), pests and predators (46.8%), lack of credit access (28.3%), poor extension service (57.4%), lack of beekeeping equipment's (45.2%) and death of colony (38.05). Similarly, poor market linkage (84.1%), lack of market information (66.2%), poor infrastructure (61.5%), low price of product (60.7%), weak bargaining power of farmers (37.5%), long-distance to market (88.4%), shortage of packing and storage materials (57.6%), presence of illegal traders (53.5%) and absence of branding (60.3%) are factors that influence honey marketing in the study area. The econometric result showed that variable cost, age of the respondent, marital status, experience, and hive number owned influence the level of honey production. The policy should focus on creating access to modern honey bee technologies, providing capacity building for producers, organizing cooperatives, providing credit services, promoting the involvement of private sectors, establishing linkages among honey producers, researchers, and private sectors.

Few recent studies have examined patient reported outcomes (PROs) during pre- or post-operative radiation therapy (RT) for soft tissue sarcoma (STS), and none have used PROMIS. This study aims to examine PROMIS scores across

-operative time points for patients receiving pre- or post-operative RT.

Anxiety, depression, pain interference, and physical function PROMIS domains were collected at the pre-operative (1), immediate post-operative (2), and post-treatment completion (3) timepoints for patients undergoing surgery and either pre-operative or post-operative RT. Median scores were compared between groups using the Kruskal-Wallis test. The reliable change index was used to determine minimum important change in PROMIS scores and to compare scores between timepoints.

95 patients were included (19 pre-operative, 76 post-operative). Both groups had significant decreases in function during treatment. Patients with wound complications were more likely to have significant increases in anxiety (36.4% vs. 8.3%; p=0.