Bunncurry4449

A majority of patients with glioneuronal tumors present with seizures. Although a number of studies have shown that greater extent of resection improves overall patient survival, few studies have focused on post-operative seizure outcome after resection of these tumors. We aim to characterize seizure control rates in patients undergoing glioneuronal tumor resection and evaluate the association between poor seizure outcome and tumor recurrence or progression.

The study population included patients who had undergone resection of glioneuronal tumors between 2014 and 2019 at our institution. Seizure outcome was assessed using Engel grading. Preoperative seizure characteristics, tumor characteristics, surgical factors, and postoperative seizure outcomes were reviewed.

26 patients (n=16, temporal lobe; n=6, frontal lobe; n=4, parietal lobe) with mean seizures duration of 56.9-months, were assessed. Histopathologically, n=15 dysembryoplastic neurepithelial tumour, n=7 ganglioglioma and n=4 Diffuse lepto-meningeal neuroepithelial tumour. There were 2 cases of complex DNET and one case of DLMNT had associated cortical dysplasia. At mean follow-up of 49.7 months, n=20 Engel 1, n=4 Engel 2 and n=2 had Engel 3 outcome. n=20 underwent gross total excision (n=18 Engel 1 and n=2 Engel 2) and n=6 sub-total excision. Among the 4 patients who needed resurgery, two were in Engel 2 and another two were in Engel 3.

Good seizure-outcome is likely associated with extent of resection. Younger age of patient, less than one-year of seizure duration and absence of generalization of seizure are good prognostic indicators. this website The best seizure-control can be achieved by early surgical intervention.

Good seizure-outcome is likely associated with extent of resection. Younger age of patient, less than one-year of seizure duration and absence of generalization of seizure are good prognostic indicators. The best seizure-control can be achieved by early surgical intervention.

Risk factors and functional outcome of hemorrhagic transformation (HT) after mechanical thrombectomy (MT) are to be elucidated in paitents with acute large vessel occlusion stroke.

We retrospectively analyzed data from 88 patients who underwent MT treatment. Independent risk factors of hemorrhagic infarction (HI), parenchymal hematoma (PH) and symptomatic intracranial hemorrhage (sICH) were implemented to determine. Association between HI, PH, sICH and mortality at 90 days after treatment were analyzed.

Of 88 patients, 44.3%had HT(n=39). 64.1% had HI (n=25), 35.9% had PH(n=14) and 12.5% had sICH (n=11). Independent risk factors for HI were associated with higher NIHSS score (OR,1.190;95% CI,1.073~1.319,P=0.001,per 1 score increase) , history of coronary heart disease (OR,4.645;95% CI,1.092~19.758,P=0.038),and use of intravenous thrombolysis (OR,3.438;95% CI,1.029~11.483,P=0.045). Independent risk factors for PH were associated with higher NIHSS score (OR,1.227;95% CI,1.085~1.387,P=0.001,per 1 score incrvenous thrombolysis was associated with HI. History of oral anti-platelet and/or anti-coagulation drugs was associated with PH. Increased systolic blood pressure was associated with sICH. PHs was remarkablely associated with mortality at 90 days.Skull base cephaloceles (SBCs) are defined as herniation of intracranial content through the skull base and are classified based on composition, etiology, and topographic location. Anterior SBCs frequently protrude in the sinonasal cavity, and consequently are at potential risk of infection. Therefore, the current recommendation is to treat SBCs with the primary intent of preventing meningitis, and surgery represents the mainstay of treatment. Anterior SBCs may display a wide spectrum of severity and complexity, and in each case the risks and benefits of surgical approaches are to be carefully weighted based on thorough assessment of symptoms, age, general conditions, location and size of the lesion, as well as expertise of the surgeon. In the last 30 years, the evolution and diffusion of transnasal endoscopic surgery have substantially changed the surgical management of the majority of SBC. In the past, they were treated exclusively with open transcranial approaches that may be burdened by relevant morbidity and risk for severe complications. link2 The transnasal endoscopic corridor now provides easy access to the lesion and different reconstructive strategies using endonasal pedicled flaps, without any external incision, cranioplasty or brain manipulation. However, there are still scenarios in which an exclusive transnasal endoscopic route is contraindicated. The aim of the present review was to provide an overview on the comprehensive management of anterior SBC, with a particular focus on lesions suitable for endoscopic surgery. Furthermore, special aspects of SBC management in children and adults will be highlighted.

Recent studies suggest gliomas location may be correlated with specific biological signatures. Our purpose was to focus on the possible correlation between MGMT metilation status and Ki67 positivity with patient age, glioma location and lateralization.

We performed a retrospective evaluation to assess the correlation between MGMT metilation status and Ki67 index positivity with patient age, glioma location and lateralization.

The study included 174 supratentorial gliomas. Of these, 144 tumors were high grade gliomas (HGGs) and 30 tumors were low grade gliomas (LGGs). In HGG group we detected an association between tumor location and MGMT status. Those GBMs located in the frontal lobe were significantly associated with MGMT methylated status (MGMT+) and Ki67<30% than those GBMs located in other sites; while those GBMs located in the temporal lobe were associated with MGMT unmethylated (MGMT-) status. In anaplastic gliomas, we found an association between the involvement of the frontal lobe with MGMT+ cation are more amenable to radical surgical resection, it may be assumed that frontal tumor can have a better prognosis, and we have shown, to our knowledge for the first time, this is true both for HGG and for LGG.

Microvascular free-tissue transfer (M-FTT) is a surgical technique for traumatic injuries that allows tissue reconstruction based on donor tissue composition. The aim of this study is to describe the surgical experiences of M-FTT for reconstruction of complex soft tissue injuries in the lower extremities of a Hispanic population.

This is a descriptive study of all M-FTT procedures performed by a single plastic surgeon from 2012 to 2016 at Puerto Rico Medical Center. Demographics, admission diagnosis, mechanism of trauma, type of free flap, co-morbidities, length of stay, donor site and complications were evaluated.

Eight patients who underwent single M-FTT procedures at lower extremity were enrolled in the study. The average age at time of surgical reconstruction was 36.9+13.2 years with six males and two females. The transfer procedures were performed using donor sites of six rectus abdominis flaps and 2 radial forearm flaps. Posterior tibial artery was used in 62.5% and popliteal artery were used in 37.5% as recipient arteries. Average surgical time was 4.4+0.7 hours with an average length of hospital stay of 22.9+20.1 days. Post-operative complications were reported in three M-FTT procedures two cases who suffered venous thrombosis and one case who suffered partial necrosis.

The M-FTT offers an adequate surgical option for patients who present with complex soft tissue traumatic injuries at the lower extremities.

The M-FTT offers an adequate surgical option for patients who present with complex soft tissue traumatic injuries at the lower extremities.

Postpartum depression (PPD) has negative effects on the mothers who experience it. The aims of the study described herein were to determine the prevalence of PPD and to determine the correlations between PPD and perceived social support, quality of life, and the risk factors for PPD.

Data were collected using a questionnaire prepared by the researchers and that included the Edinburgh Postnatal Depression Scale, the Beck Depression Scale, the Quality of Life scale, the Multidimensional Scale of Perceived Social Support, and questions regarding the sociodemographic characteristics and PPD risk factors of the mother.

The prevalences of PPD were found to be 3.9% in the 4th week postpartum and 5.9% in the 6th week postpartum. Being a primary school (and no higher) graduate, being stressed in daily life, experiencing health problems during the delivery and the postpartum period, and not thinking of oneself as a good mother were all determined to be risk factors for PPD. Although the mean score for social support was higher in women with low PPD risks, this difference was not significant. According to a linear regression model, PPD negatively affected the social and psychological qualities of life of the mothers in the 4th week postpartum.

Along with a trend suggesting a correlation between high social support and low PPD risk in women, a correlation between low PPD risk and high quality of life was also found.

Along with a trend suggesting a correlation between high social support and low PPD risk in women, a correlation between low PPD risk and high quality of life was also found.

The aim of this study was to examine the effects of eating dried figs on the symptoms of primary dysmenorrhea, perceived stress levels, and quality of life during all menstrual cycles.

This randomized, placebo-controlled study was performed with 115 midwifery students. Each student was randomly assigned to the placebo (n = 31), cinnamon (n = 33), or dried fig (n = 34) groups. Data were gathered through the Total Dysmenorrhea Score, a descriptive information form, the Visual Analogue Scale, a pain duration assessment form, the Menstrual Distress Questionnaire, the Perceived Stress Scale, and the short version of the World Health Organization Quality of Life Scale-TR.

During the 3 menstrual cycles in which the intervention was implemented, the dried-fig group had significantly lower scores for pain severity and duration, menstrual distress, and perceived stress than did those of the cinnamon and placebo groups. link3 In addition, during these 3 cycles, the dried-fig group had significantly higher quality-of-life scores than the cinnamon and placebo groups.

The results showed that eating dried figs during menstruation decreased pain severity and duration, menstrual symptoms, and perceived stress and increased quality of life.

The results showed that eating dried figs during menstruation decreased pain severity and duration, menstrual symptoms, and perceived stress and increased quality of life.

To test the hypothesis that fermentable fiber prevents Salmonella typhimurium infection-associated symptoms by enhancing innate and adaptive immune system in neonatal pigs.

Two-d-old piglets (n=120) were randomized to receive either a nutritionally complete sow milk replacer formula (CON), or supplemented with methylcellulose (MCEL-non-fermentable), soy polysaccharides (SPS-moderately fermentable), or fructooligosaccharides (FOS-highly fermentable). On d7, piglets received an oral gavage of S. typhimurium-798, and continued receiving the same diets up to 48h post-infection. Ileal mucosal samples were obtained for further analyses.

A reduction in chloride secretion was observed in FOS when compared to other diets (p<0.0003). The number of ileal sulfo-acidomucins was higher (p<0.05) in FOS before infection compared with other diets. NFkB was inhibited in FOS following infection (p<0.05), when compared with CON. IL-1β expression was increased at 4h post-infection (p<0.05) in CON; however, this response was attenuated in the fiber groups.