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Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is performed by examination of the Electrocardiogram (ECG) by a cardiologist. This method of diagnosis is hampered by the lack of accessibility to expert cardiologists. For quite some time, signal processing methods had been used to automate arrhythmia diagnosis. However, these traditional methods require expert knowledge and are unable to model a wide range of arrhythmia. Recently, Deep Learning methods have provided solutions to performing arrhythmia diagnosis at scale. However, the black-box nature of these models prohibit clinical interpretation of cardiac arrhythmia. There is a dire need to correlate the obtained model outputs to the corresponding segments of the ECG. To this end, two methods are proposed to provide interpretability to the models. The first method is a novel application of Gradient-weighted Class Activation Map (Grad-CAM) for visualizing the saliency of the CNN model. In the second approach, saliency is derived by learning the input deletion mask for the LSTM model. The visualizations are provided on a model whose competence is established by comparisons against baselines. The results of model saliency not only provide insight into the prediction capability of the model but also aligns with the medical literature for the classification of cardiac arrhythmia.Clinical relevance- Adapts interpretability modules for deep learning networks in ECG arrhythmia classfication, allowing for better clinical interpretation.Recent developments in the field of deep learning has shown a rise in its use for clinical applications such as electrocardiogram (ECG) analysis and cardiac arrhythmia classification. Such systems are essential in the early detection and management of cardiovascular diseases. However, due to privacy concerns and also the lack of resources, there is a gap in the data available to run such powerful and data-intensive models. To address the lack of annotated, high-quality ECG data for heart disease research, ECG data generation from a small set of ECG to obtain huge annotated data is seen as an effective solution. Generative Feature Matching Network (GFMN) was shown to resolve few drawbacks of commonly used generative adversarial networks (GAN). Based on this, we developed a deep learning model to generate ECGs that resembles real ECG by feature matching with the existing data.Clinical relevance- This work addresses the lack of a large quantity of good quality, publicly available annotated ECG data required to build deep learning models for cardiac signal processing research. We can use the model presented in this paper to generate ECG signals of a target rhythm pattern and also subject-specific ECG morphology that could improve their cardiac health monitoring while maintaining privacy.Arrhythmia is a serious cardiovascular disease, and early diagnosis of arrhythmia is critical. In this study, we present a waveform-based signal processing (WBSP) method to produce state-of-the-art performance in arrhythmia classification. When performing WBSP, we first filtered ECG signals, searched local minima, and removed baseline wandering. Subsequently, we fit the processed ECG signals with Gaussians and extracted the parameters. Afterwards, we exploited the products of WBSP to accomplish arrhythmia classification with our proposed machine learning-based and deep learning-based classifiers. find more We utilized MIT-BIH Arrhythmia Database to validate WBSP. Our best classifier achieved 98.8% accuracy. Moreover, it reached 96.3% sensitivity in class V and 98.6% sensitivity in class Q, which both share one of the best among the related works. In addition, our machine learning-based classifier accomplished identifying four waveform components essential for automated arrhythmia classification the similarity of QRS complex to a Gaussian curve, the sharpness of the QRS complex, the duration of and the area enclosed by P-wave.Clinical relevance- Early diagnosis and automated classification of arrhythmia is clinically essential.Machine learning has become increasingly useful in various medical applications. One such case is the automatic categorization of ECG voltage data. A method of categorization is proposed that works in real time to provide fast and accurate classifications of heart beats. This proposed method uses machine learning principles to allow for results to be determined based on a training dataset. The goal of this project is to develop a method of automatically classifying heartbeats that can be done on a low level and run on portable hardware.As hospital workers face a growing number of patients and have to meet increasingly rigorous standards of care, their ability to successfully modulate their emotional reactions and flexibly handle stress presents a significant challenge. This paper examines a multimodal signal-driven way to quantify emotion self-regulation and stress spillover through a dynamical systems model (DSM). The proposed DSM models day-to-day changes of emotional arousal, captured through speech, physiology, and daily activity measures, and its interplay with daily stress. The parameters of the DSM quantify the degree of self-regulation and stress spillover, and are associated with work performance and cognitive ability in a multimodal dataset of 130 full-time hospital workers recorded over a 10-week period. Linear regression experiments indicate the effectiveness of the proposed features to reliably estimate individuals' work performance and cognitive ability, providing significantly higher Pearson's correlations compared to aggregate measures of emotional arousal. Results from this study demonstrate the importance of quantifying oscillatory behaviors from longitudinal ambulatory signals and can potentially deepen our understanding of emotion self-regulation and stress spillover using signal-driven measurements, which complement self-reports and provide estimates of the psychological constructs of interest in a fine-grained time resolution.

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