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206±85×10

/L, respectively; P=0.010), and the rate of planned ICU admission (elective surgery) was higher in the worse hearing group (57.1% vs. 28.8%, respectively; p=0.011).

Age, sex, and the use of furosemide did not have adversely affect hearing function. Low serum platelet count and planned admission appear to be risk factors for worse hearing.

Age, sex, and the use of furosemide did not have adversely affect hearing function. Low serum platelet count and planned admission appear to be risk factors for worse hearing.The objective was to evaluate the pure-tone audiogram-based screening protocols in VS diagnostics. We retrospectively analyzed presenting symptoms, pure tone audiometry and MRI finding from 246 VS patients and 442 controls were collected to test screening protocols (AAO-HNS, AMCLASS-A/B, Charing Cross, Cueva, DOH, Nashville, Oxford, Rule3000, Schlauch, Seattle, Sunderland) for sensitivity and specificity. Results were pooled with data from five other studies, and analysis of sensitivity, specificity and positive likelihood ratio (LR+) for each protocol was performed. Our results show that protocols with significantly higher sensitivity (AMCLASS-A/B, Nashville) show also significantly lowest specificity, and tend to have low association (positive likelihood ratio, LR+) to the VS. The highest LR+ was found for protocols AAO-HNS, Rule3000 and Seattle. In conclusions, knowing their properties, screening protocols are simple decision-making tools in VS diagnostic. selleck chemicals llc To use the advantage of the highest sensitivity, protocols AMCLASS-A + B or Nashville can be of choice. For more reasonable approach, applying the protocols with high LR+ (AAO-HNS, Rule3000, Seattle) may reduce the overall number of MRI scans at expense of only few primarily undiagnosed VS.

The video head impulse test (vHIT) is used as a measure of compensation yet it's stability in patients with vestibular pathology is unknown.

144 patients (n=72 female, mean 54.46±15.8 years) were grouped into one of three primary diagnoses (Peripheral, Central, or Mixed). Subjects were further categorized based on sex (male versus female), ear (left versus right; ipsilesional versus contralesional), age (six groups ranging from 19 to 84 years), and duration between visits (five groups, mean 191.46±SE 29.42 days, median 55.5 days). The gain of the VOR during passive head rotation was measured for each semicircular canal (horizontal, anterior, posterior).

There was no difference in the VOR gain within any semicircular canal between the two visits (horizontal p=0.179; anterior p=0.628; posterior p=0.613). However, the VOR gain from the horizontal canals was higher than the vertical canals for each visit (p<0.001). Patients diagnosed with peripheral vestibular pathology had significantly lower (p≤0.001) horizontal semicircular canal gains at each visit. There was no difference in VOR gain between sex (p=0.215) or age groupings (p=0.331). Test-retest reliability of vHIT in patient subjects is good (ICC=0.801) and the VOR gain values across two separate visits were significant and positively correlated (r=0.67) regardless of sex, ear, age, or duration between visits.

The vHIT is a stable measure of VOR gain over two different times across a variety of vestibular patients with no influence of age or sex.

The vHIT is a stable measure of VOR gain over two different times across a variety of vestibular patients with no influence of age or sex.

The goal of this study is to analyze the clinical view of patients with direction-fixed positional nystagmus (DFPN) following head-roll maneuver.

Sixty patients with DFPN were reviewed retrospectively. Patients were categorized into 3 groups according to the direction of nystagmus based on rotation side. Associated problems were documented, and cumulative data were compared between groups. One-way analysis of variance (ANOVA test) was used for statistical analysis (

<0.05).

Thirty-three patients (55%) had stronger nystagmus beating towards the direction of head-roll (Group-A). Three patients developed geotropic LC-BPPV. Fourteen patients had inner ear disease. Sixteen patients (27%) had stronger nystagmus beating against the direction of head roll (Group-B). Nine patients had inner ear disease. None of the patients tested with head-shaking had change of direction of nystagmus. Eleven patients (18%) had DFPN with equal velocity during right or left head-roll maneuver (Group-C). Of those, nine patient. Head-shaking testing is recommended to expose the lateral canal BPPV. But the incidence is low.

Severe bleeding following cardiac surgery remains a troublesome complication, but to date, there is a lack of comprehensive predictive models for the risk of severe bleeding following off-pump coronary artery bypass grafting (OPCABG). This study aims to analyze relevant indicators of severe bleeding after isolated OPCABG and establish a corresponding risk assessment model.

The clinical data of 584 patients who underwent OPCABG from January 2018 to April 2020 were retrospectively analyzed. We gathered the preoperative baseline data and postoperative data immediately after intensive care unit admission and used multifactor logistic regression to screen the potential predictors of severe bleeding, upon which we established a predictive model. Using the consistency index and calibration curve, decision curve, and clinical impact curve analysis, we evaluated the performance of the model.

This study is the first to establish a risk assessment and prediction model for severe bleeding following isolated OPCABG.therefore worthy of further exploration and verification.

To investigate the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on cardiovascular outcomes in elderly Chinese patients with comorbid coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM).

A retrospective cohort study was conducted on 501 elderly inpatients (≥ 60 years) with comorbid CHD/T2DM in Department of Cardiovascular Medicine and Endocrinology, Chinese PLA General Hospital from January 2018 to December 2019. These patients were divided into two groups according to the administration of SGLT2i. All the demographic characteristics and clinical data were collected. Cardiovascular outcomes, including all-cause mortality, major adverse cardiovascular events (MACE), and hospitalization for heart failure (HHF), were followed up.

In the cohort, there were 167 patients in the SGLT2i group and 334 patients in the control group. In the efficacy analyses, the incidence of MACE was lower in the SGLT2i group than in the control group 3.6%

. 9.3% (

= 0.022). A lower risk of MACE was observed in the SGLT2i group [hazard ratio (HR) = 0.