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The IIEF-5 questionnaire is a validated scale used as a diagnostic tool in erectile dysfunction (ED). This simplified version includes five items that focus on erectile function and satisfaction during sexual intercourse; it has favourable properties for detecting the presence and severity of erectile dysfunction The main objective of this study was to make a cross-cultural adaptation to Spanish of the IIEF-5 scale and to evaluate its psychometric properties of validity, reliability, and feasibility in the Spanish population. Validation of the IIEF-5 included (i) professional translation of the scale; (ii) scientific evaluation of the translation; (iii) professional retranslation; (iv) assessment of 10 individuals to test correct comprehension and idiomatic adequacy; (v) validation of the IIEF-5 by an online survey. The study sample consisted of 100 participants, who received the online form either directly or through other participants who distributed it. Participants obtained a mean score of 22.3 (SD 2.7), implying normal erectile function. However, 23 results of mild dysfunction (n = 23) and 2 of mild to moderate dysfunction (5.1%) were identified. A Cronbach's alpha coefficient of 0.75 was obtained for the total of the final questionnaire, indicating high reliability. Validity analysis had a value of 0.784 (>0.5) and was therefore considered appropriate. The IIEF-5 scale is a reliable tool to test ED, and its Spanish version is satisfactorily understood by patients.Car sharing services have expanded in order to meet the new necessities of mobility worldwide in an innovative way. Before the COVID-19 pandemic, car sharing was a very popular mode of transportation among young adults in big cities. However, during this ongoing pandemic and with public transportation considered a super-spreading transmitter, the usage of car sharing is unclear. Therefore, the aim of this study, which is explorative in nature, is to investigate the usage, advantages, drivers, and barriers to car sharing during this ongoing pandemic era. To this end, 66 interviews were conducted among users of car sharing during the COVID-19 pandemic. The findings provide key information for the planning of car sharing operations and public transportation in the context of avoiding COVID-19 infection and respecting the recommendations of local governments. In addition, new emerging profiles of car sharing users in the ongoing pandemic are identified. This research provides relevant insights for both business practice and policy makers.The current research was aimed to study the effects of different land use types (LUT) and soil depth (SD) on soil enzyme activity, metal content, and soil fungi in the karst area. Soil samples with depths of 0-20 cm and 20-40 cm were collected from different land types, including grassland, forest, Zanthoxylum planispinum land, Hylocereus spp. land and Zea mays land. The metal content and enzyme activity of the samples were determined, and the soil fungi were sequenced. The results showed that LUT had a significant effect on the contents of soil K, Mg, Fe, Cu and Cr; LUT and SD significantly affected the activities of invertase, urease, alkaline phosphatase and catalase. In addition, Shannon and Chao1 index of soil fungal community was affected by different land use types and soil depths. Ascomycota, Basidiomycota and Mortierellomycota were the dominant phyla at 0-20 cm and 20-40 cm soil depths in five different land types. Land use led to significant changes in soil fungal structure, while soil depth had no significant effect on soil fungal structure, probably because the small-scale environmental changes in karst areas were not the dominant factor in changing the structure of fungal communities. Additionally, metal element content and enzyme activity were related to different soil fungal communities. In conclusion, soil mineral elements content, enzyme activity, and soil fungal community in the karst area were strongly affected by land use types and soil depths. This study provides a theoretical basis for rational land use and ecological restoration in karst areas.This paper explores the effects of environmental regulation (ER) and rural residents' health investment (RRHI) on agricultural eco-efficiency (AEE) to provide a reference for the Chinese Government and other developing countries for implementing environmental regulation policies and to provide new paths to further improve green development in agriculture. Using the panel data of 31 Chinese provinces from 2009-2018, the Super-SBM model was used to measure AEE. The role of ER on AEE was analyzed based on panel two-way fixed effects with endogeneity treatment and a robustness test, and this mediating effect analysis was conducted to analyze the role of RRHI in ER and AEE, examining the extent of the effect of ER on AEE in three regions of China-eastern, central and western-using a heterogeneity analysis. The results of the study show that (1) from a national perspective, ER has a significant positive impact on AEE, showing that ER is effective at this stage; (2) when RRHI is used as a mediating variable, the rising ER's intensity can promote AEE by increasing RRHI; and (3) the results of the heterogeneity analysis show that ER has the greatest impact on AEE in the economically developed eastern region; the western region with a weaker level of economic development is in second place. However, ER has a negative impact on AEE in the central region with a medium level of economic development. Thus, the impact of ER on AEE will show great differences depending on the stage of economic development.Human exposure to organophosphate esters (OPEs) is more pervasive in industrial areas manufacturing OPE-related products. OPE exposure is of great concern due to its associations with adverse health effects, while studies on OPE exposure in industrial districts are scarce. This study aimed to assess human exposure to OPEs in a typical industrial area producing large amounts of OPE-related products in Shenzhen, China. Tris (2-chloroethyl)-phosphate (TCEP), tris (2-chloroisopropyl) phosphate (TCPP) and other common OPEs were analyzed in urine (n = 30) and plasma (n = 21) samples. Moreover, we measured five OPE metabolites (mOPEs) in plasma samples (n = 21). The results show that TCPP and TCEP are dominant compounds, with moderate to high levels compared with those reported in urine and plasma samples from other regions. In addition, di-n-butyl phosphate (DnBP) and diethyl phosphite (DEP) were frequently detected in plasma samples and could be considered as biomarkers. Risk assessment revealed a moderate to high potential health risk from TCEP exposure. Our results provide basic data for human exposure to OPEs in industrial areas and call for the prevention and mitigation of industrial chlorinated OPE pollution.The global COVID-19 pandemic has revealed the extent to which schools are struggling with the provision of safe drinking water, sanitation and hygiene (WASH). To describe the WASH conditions in schools and discuss the implications for the safe reopening of schools during the ongoing COVID-19 pandemic, a systematic review of peer-reviewed literature on WASH in schools in low- and middle-income countries was performed. In April 2021, five databases, including MEDLINE (via PubMed), Web of Science, Scopus, AJOL, and LILACS, were used to identify studies. Sixty-five papers met the inclusion criteria. We extracted and analyzed data considering the Joint Monitoring Programme (JMP) definitions and the normative contents of Human Rights to safe drinking water and sanitation. Publications included in this systematic review considered 18,465 schools, across 30 different countries. Results indicate a lack of adequate WASH conditions and menstrual hygiene management requirements in all countries. The largely insufficient and inadequate school infrastructure hampers students to practice healthy hygiene habits and handwashing in particular. check details In the context of the COVID-19 pandemic, being hindered to implement such a key strategy to contain the spread of SARS-CoV-2 in the school environment is of major concern.Medication use can increase the risk of falls and injuries in nursing homes, creating a significant risk for residents. We performed a retrospective cohort study over one year to identify the incidence of drug-related falls with and without injury among four Japanese nursing homes with 280 beds. We evaluated the relationship between potential risk factors for falls and fall-related injuries while considering well-known risks such as ADLs and chronic comorbidities. By collaboratively reviewing care records, we enrolled 459 residents (mean age, 87) and identified 645 falls, including 146 injurious falls and 16 severe injurious falls requiring inpatient care, incidence 19.5, 4.4, 0.5 per 100 resident-months, respectively. Medication influenced around three-quarters of all falls, >80% of which were psychotropic drugs. Regularly taking ≥5 medications was a risk factor for the initial falls (HR 1.33 CI 1.00-1.77, p = 0.0048) and injuries after falls (OR 2.41 CI 1.30-4.50, p = 0.006). Our findings on the incidence of falls with and without injury were similar to those in Western countries, where the use of psychotropic medication influenced >50% of falls. Discontinuing unnecessary medication use while simultaneously assessing patient ADLs and comorbidities with physicians and pharmacists may help to avoid falls in nursing homes.Ecosystem service values (ESVs) are crucial to ecological conservation and restoration, urban and rural planning, and sustainable development of land. Therefore, it is important to study ESVs and their driving factors in the Dongting Lake Eco-Economic Zone (Dongting Lake). This paper quantifies the changes in ESVs in the Dongting Lake using land use data from 2000, 2005, 2010 and 2018. The eXtreme Gradient Boosting (XGBoost) model is used to study the effects of individual driving factors and the synergistic effects of these driving factors on ESVs. Our analysis suggests that (1) From 2000 to 2018, the largest dynamic degree values in the Dongting Lake are in unused land types, followed by construction lands and wetlands. The ESVs of the Dongting Lake show an increasing trend, with those of forestlands being the highest, accounting for approximately 44.65% of the total value. Among the ESVs functions, water containment, waste treatment, soil formation and protection, biodiversity conservation and climate regulation contribute the most to ESVs, with a combined contribution of 76.64% to 76.99%; (2) The integrated intensity of anthropogenic disturbance shows a U-shaped spatial distribution, decreasing from U1 to U3. The driving factors in descending order of importance are the human impact index, total primary productivity (GPP), slope, elevation, population, temperature, gross domestic product, precipitation and PM2.5; (3) When the GPP is low (GPP < 900), the SHAP (SHapley Additive exPlanation) value of the high human impact index is greater than zero, indicating that an increase in GPP increases the ESVs in the Dongting Lake. This study can provide technical support and a theoretical basis for ecological environmental protection and ecosystem management in the Dongting Lake.