Kastruplinnet9946

With this optimal cell distribution window, in vivo studies showed that the photosensitive stem cells via both intratumoral and intravenous injections successfully inhibited breast cancer cell growth and decreased the tumor recurrence rate post PTT. Our results support that this photo-integrated platform with stable optical properties is promising to achieve real-time tracking and measure the cell distribution quantitatively with high spatiotemporal resolution for stem cell therapy.Solid strong bases with an ordered pore structure (OPS-SSBs) have attracted much attention because of their high catalytic activity and shape selectivity as heterogeneous catalysts in various reactions. Nevertheless, high temperatures are required to fabricate OPS-SSBs by using traditional methods. Herein, we report for the first time that the coordination solvents affect basicity generation in metal-organic frameworks (MOFs) greatly and that strong basicity can be formed at comparatively low temperatures. A typical MOF, MIL-53, was employed, and three different solvents, namely, water, methanol, and N,N-dimethylformamide (DMF), were coordinated, respectively, by means of solvent exchange. Thermogravimetry-mass spectrometer analysis shows that the conversion temperature of base precursor KNO3 is quite different on MIL-53 coordinated with different solvents. The conversion of KNO3 to basic sites takes place at 350, 300, and 250 °C on MIL-53 coordinated with water, methanol, and DMF, respectively. It is fascinating to observe the generation temperature of strongly basic sites at 250 °C, which is noticeably lower than that on various supports, such as mesoporous silica SBA-15 (600 °C), zeolite Y (700 °C), and metal oxide ZrO2 (730 °C). This is due to the redox interaction between coordination solvents and KNO3, leading to a significant decrease in the temperature for KNO3 conversion. Consequently, OPS-SSBs were prepared successfully with an ordered pore structure and strong basicity. The obtained OPS-SSBs show good shape selectivity in Knoevenagel condensation of aromatic aldehydes with different active methylene compounds. Moreover, these solid bases are highly active in the synthesis of dimethyl carbonate through transesterification reaction. This work might open up a new avenue for the fabrication of various functional materials at low temperatures through redox interactions.Over the last years, bioactive glass particles have been successfully incorporated in dental restorative materials. Remineralizing effects on dental hard tissue and antibacterial properties are promising properties of these customized composites. A few materials doped with bioactive fillers are already available on the dental market. Nevertheless, further research is required to fine-tune bioactive composites for biomimetic restorative approaches.The dynamics of microscopic marine plankton in coastal areas is a fundamental theme in marine biodiversity research, but studies have been limited because the only available methodology was collection of plankton using plankton-nets and microscopic observation. In recent years, environmental DNA (eDNA) analysis has exhibited potential for conducting comprehensive surveys of marine plankton diversity in water at fixed points and depths in the ocean. However, few studies have examined how eDNA analysis reflects the actual distribution and dynamics of organisms in the field, and further investigation is needed to determine whether it can detect distinct differences in plankton density in the field. To address this, we analyzed eDNA in seawater samples collected at 1 km intervals at three depths over a linear distance of approximately 3.0 km in the Seto Inland Sea. The survey area included a location with a high density of Acoela (Praesagittifera naikaiensis). However, the eDNA signal for this was little to none, and its presence would not have been noticed if we did not have this information beforehand. Meanwhile, eDNA analysis enabled us to confirm the presence of a species of Placozoa that was previously undiscovered in the area. In summary, our results suggest that the number of sequence reads generated from eDNA samples in our project was not sufficient to predict the density of a particular species. However, eDNA can be useful for detecting organisms that have been overlooked using other methods.Acoels, belonging to Xenacoelomorpha, are small worms with a relatively simple body plan and are considered a critical clade for understanding the evolution of bilaterians. Despite acoels' importance, however, many undiscovered species are predicted to be present worldwide. Here, we describe a new marine acoel species, Amphiscolops oni sp. nov., based on materials collected from the intertidal and subtidal zones of rocky shores at several localities along the Japanese Pacific coast. The new species is approximately 3 mm long and shows typical characteristics of the family Convolutidae, such as the presence of eyespots, symbiosis with algae, position of the gonopores, morphology of the bursal nozzles, lack of central singlet microtubules in the axonemes of spermatozoa, and funnel-like posture of the anterior end. Based on morphology and the results of molecular phylogenetic analyses, we assign this species to the genus Amphiscolops. Interestingly, these worms show unique behaviors such as swimming by flapping the lateral sides and actively capturing prey by swinging the anterior funnel. Furthermore, they possess a dorsal appendage-a characteristic previously unreported in Xenacoelomorpha-representing an evolutionary novelty acquired by this species.We describe a new typhlotanaid species, Hamatipeda kohtsukai sp. nov., collected from between 167 and 488 m depth in the Sagami Sea, Japan. This is the first record of Hamatipeda from the northern hemisphere. Hamatipeda kohtsukai resembles Hamatipeda trapezoida from the Subantarctic region in having pereonites 1-3 widest anteriorly (not rectangular), but differs from it in the length ratio of antennal articles 4/5; the number of setae on the dactyli of pereopods 1-3, ischia of pereopods 4-6, and carpi of pereopods 4-6; the shape of the unguis of pereopods 4-6; and the shape of the uropodal endopod. We determined partial sequences for the cytochrome c oxidase subunit I (COI; cox1) and 18S rRNA (18S) genes in H. kohtsukai. A phylogenetic reconstruction based on the 18S sequences recovered a highly supported Typhlotanaidae clade containing H. kohtsukai and Typhlotanais mixtus, with Paranarthrura sp. (Agathotanaidae) as the sister taxon. A key to species of Hamatipeda is presented.Gnathiid larvae (Crustacea; Isopoda; Gnathiidae) infesting elasmobranch and holocephalan fishes from mainly bathyal depths off Suruga Bay, off Kume-jima Island, and five sites from off Tokyo Bay to Shimoda City, Japan were examined. A total of 1460 gnathiid larvae were sampled from 87 host individuals belonging to seven families and 10 species. The morphology of these larvae was distinguishable from other gnathiid species by the head appendages. These larvae presented two pigmentation patterns, stripes or spots, on their dorsal thoraxes in live specimens. Furthermore, they were determined as the second and third stage praniza larvae on the basis of allometric variance of maximum head and abdomen widths. A third stage praniza with stripe pigmentation metamorphosed into an adult male and could be identified as a new species of the genus Thaumastognathia Monod, 1926. The duration between detachment from the host and metamorphosis into male adult required 204 days. This paper describes Thaumastognathia bicorniger sp. nov. on the basis of P3/stripe larvae and the male adult. This report is the first record of the larva and host information for a species of Thaumastognathia.A new species of the family Splanchnotrophidae Norman and Scott, 1906 (Cyclopoida) is described based on both sexes collected from off the Oki Islands, the Sea of Japan. Specimens of both sexes of Ceratosomicola oki n. sp. were found in the body cavities of Glossodoris misakinosibogae Baba, 1988 (Nudibranchia Chromodorididae). ONO-AE3-208 The copepod is characterized by the following female characters the cephalosome with a pair of dorsolateral horn-like processes; the prosome with hemispherical posterolateral lobes on the middle region. Non-destructive, micro-computed tomography (micro-CT) imaging performed on a single specimen of the nudibranch revealed a heavy infection by a total 17 specimens of C. oki n. sp. Almost all individuals of the copepod were attached on the surface of the middle to posterior parts of the visceral sac, forming a dense cluster. The four females bearing developed lateral processes on the prosome faced the anterior end of the visceral sac and positioned the posterior tip of the body under the secondary gills of the host. The males fitted in the gaps between the females' bodies. Further, the distribution and shape of the reproductive organs of both sexes were partially clarified by micro-CT imaging.We describe three free-living marine nematode species from Sagami Bay, Japan. Wiesoncholaimus jambiosp. nov. is the second species of this genus. It differs from the type species, Wiesoncholaimus mawsonae Inglis, 1966, by its dorsal tooth, which is as long as the other two teeth; its conico-cylindrical tail, which is as long as 4.6-4.8 cloacal body diameters; and the absence of the gubernaculum. Thalassironus cf. britannicus de Man, 1889 agrees well with a redescription of Thalassironus britannicus de Man, 1889 based on specimens collected near the type locality. However, as it is possible that T. britannicus sensu lato includes two or more species, our species may not be conspecific to T. britannicus sensu stricto. Vasostoma cf. longispicula Huang and Wu, 2010 closely resembles Vasostoma longispicula Huang and Wu, 2010 originally described from China, but minor differentiations are observed in body diameter, body cuticle thickness, and type of precloacal supplements.A new species of amphinomid polychaete, Branchamphinome kohtsukai sp. nov., is described from Japanese waters, 29-211 m in depth. The species is distinguishable from other congeners by the following features i) branchiae with four-six filaments in midbody segments; ii) two pairs of eyes not coalescent; iii) the ventral side of the first four chaetigers broadly pigmented. This is the first record of Branchamphinome from the North Pacific Ocean. We provide a phylogenetic tree based on the sequences of four genes (COI, 16S, 18S, 28S) and discuss amphinomids' relationships.Ctenostome bryozoans were collected from depths of 150-300 m in Suruga Bay, the Kumano Sea, and off Sendai Bay on the Pacific coast of Japan. Among these samples were five new species, three of which were epibiotic on other animals. Alcyonidium clavum n. sp., found encrusting cirri of the stalked crinoid Metacrinus rotundus, was previously reported in Japan as Alcyonidium mamillatum, but differs from the latter in lacking rings on the peristome. Triticella parvacrista n. sp. and Triticella cunabula n. sp. were epibiotic on the isopod Bathynomus doederleini and the pycnogonid Ascorhynchus japonicum, respectively. This is the first record of the genus Triticella from Japanese waters. These species differ from previously described species in autozooidal morphology, particularly the dimensions of the autozooidal dilatation, in the presence or absence of the frenaculum, and in the septate junction between the dilatation and pedicel. Bockiella arcatumida n. sp., found as erect colonies on pebbles and hydroids collected off Sendai Bay, differs from previously known species in the size and arrangement of the kenozoids in the branch.