Doganbernard8699

These results provide a useful tool for the management to implement psychosocial hazards in their risk assessment and a roadmap for action plans.

Fine Kinney risk scores and classes are considered more realistic than AHP since they include actual responses of the maintenance workers to the COPSOQ II questionnaire. These results provide a useful tool for the management to implement psychosocial hazards in their risk assessment and a roadmap for action plans.This study is aimed at deciphering meanings embedded in the cultural ornaments of Guji Oromo women of Southern Ethiopia. Relevant data were collected through observation, interview, and focus group discussion which involved 30 participants. The data were analyzed thematically following the analytical framework of material culture theory. Results of the study reveal that, in addition to their beautification purpose, cultural ornaments of Guji Oromo women communicate meanings related to personal status, social identities, and the rights and privileges of the wearer. Cultural norms and restrictions govern the ornamentation practice of Guji women. Such practice of ornamentation shows the deep-rooted indigenous wisdom of the Guji society in promoting important cultural values such as virginity, marriage bond, and personal success while discouraging unacceptable practices such as sex before marriage and gender-based violence.The application of sewage sludge in soils can bring benefits to agricultural productivity, however, the risks arising from this application must be measured and carefully evaluated. Persistent organics compounds and drugs can be present in the sewage sludge and if applied to the soil, they can cause severe risks to the soil biota and contamination of groundwater. This work determined 174 persistent organic compounds and drugs in sludge samples from a wastewater treatment plant using chromatographic methods. The drugs ciprofloxacin, enrofloxacin and diclofenac were quantified, and values varied according to sampling period. For persistent organic compounds, cresols were the most abundant compounds in sewage sludge. With the analyses made of both the elutriate and the filtrate, it was possible to verify the potential for soil retention or leaching that each compound can present with the application of sewage sludge in the agriculture.The 2,6-di-O-methyl-β-cyclodextrin (dMβCD) is an amphiphilic annular compound consisting of seven dimethyl-glucose molecules. This compound is well known as a solubilizer of lipophilic compounds. Especially, dMβCD extracts cholesterol from the plasma membrane of mammalian cells and releases the cholesterol to the aqueous solution. The experimental use of dMβCD, therefore, serves to investigate the role of cholesterol in the mammalian cell membrane. It is, however, unclear as to how dMβCD extracts cholesterol incorporated into the glycerophospholipid biomembrane. Meanwhile, dMβCD acts as a beneficial compound for Helicobacter pylori and is used as the standard component for supporting the growth of this bacterium in the serum-free culture. However, the detailed mechanism of dMβCD for supporting the growth of H. pylori is still to be clarified. H. pylori is a Gram-negative microaerophilic bacillus recognized as a pathogen concerned with gastrointestinal diseases in human. Previous studies by our group have successfully obtained the H. pylori strains culturable without dMβCD and demonstrated the distinct effects of dMβCD on the interaction between H. pylori and exogenous steroidal compounds. For instance, dMβCD promotes and inhibits the absorption of cholesterol and several steroidal compounds respectively into the biomembranes of H. pylori. In this study we summarized behaviors of dMβCD toward steroidal compounds relevant to H. pylori.Correct execution of civil engineering structures depends largely on the adequate and detailed mapping of the subsurface. This can be achieved by the application of appropriate geophysical or geotechnical methods in association with a detailed information on the geological sequence of the subsurface structure. In this study, a combination of near surface seismic refraction method, cone penetration test and borehole logs were used to obtain 2-dimensional (2D) information of the subsurface geological features. These methods were used to characterize the subsurface condition of a reclaimed land in Ajah area of Lagos for the purpose of construction. The seismic refraction method revealed three geologic layers with seismic velocities ranging between 258 and 3544 m/s. Additionally, the cone penetration test revealed that the geologic formation from the topsoil to a depth of 6 m was an alluvium of soft and highly compressible property. Furthermore, the percussion drilling test also confirmed the geologic formation from the topsoil to a depth of about 6 m to be highly compressible. However, a geologic formation with good geotechnical characteristics, such as a low compressibility potential, was encountered at a depth between 7 and 16 m, which coincides with the third layer of the seismic refraction method. The results of the three methods confirmed that the depth to most competent layer must be located before the foundations of engineering constructions are sited.

To analyze the action of strontium ranelate (SR) and melatonin in isolation or in association in knees, liver and kidneys of rats Wistar with induced osteoarthritis (OA).

Thirty male rats were induced to OA through an anterior cruciate ligament transection (ACLT), and treated with melatonin and SR in isolation or in association. Morphological, histopathological, histochemical and morphometric analysis were realized of the structure of the articular capsule, as well as histopathological analysis of liver and kidneys from the animals.

The experimental model was successful. The association of the drugs presented chondroprotective pharmacodynamics. However, more successful results were identified from analysis of animals in which received melatonin in isolation, regarding biochemical parameters of glutamic oxalacetic transaminase. The prepared slide samples of liver and kidneys from groups submitted to the isolated use of SR and melatonin or the association of these drugs presented no differences, when compared to the control group.

The administration of the drugs presented chondroprotective effect and prevented from the aggravation of articulate damages, and was not capable of modifying the histology of liver or kidneys. This finding suggests a safe association for the treatment of OA, however it requires further investigation in order to expand therapeutic perspectives regarding improvements of the quality of life of individuals in our society.

The administration of the drugs presented chondroprotective effect and prevented from the aggravation of articulate damages, and was not capable of modifying the histology of liver or kidneys. This finding suggests a safe association for the treatment of OA, however it requires further investigation in order to expand therapeutic perspectives regarding improvements of the quality of life of individuals in our society.Before disposal of any metallurgical waste to the environment, it is the responsibility of mining institutes to adhere to the permissible metal content limits. Base metals, especially iron and copper, have adverse effects of reducing the soil pH and excessive concentrations of these in the disposed waste may result in soil pollution and toxicity, with adverse effects on plant growth and animal health. Copper slag is a metallurgical waste that is disposed by way of stockpiling at designated dump sites within a mining site. The observed depletion of high-grade iron ores in Botswana and the environmental hazards associated with disposal of untreated metallurgical waste, presents an opportunity for research on secondary sources of iron and copper. Our characterization results show that this BCL copper slag is a good secondary source of base metals, especially iron and copper. These results reveal that the elemental proportion of iron was around 35.4%. Literature states that an iron grade that is considered viableron for beneficiation purposes.The human immune system presents remarkable inter-individual variability in response to pathogens or perturbations. Recent high-throughput technologies have enabled the identification of both heritable and non-heritable determinants of immune response variation between individuals. In this review, we summarize the advances made through the Human Functional Genomics Projects (HFGPs), challenges and the need for more refined strategies. Inter-individual variability in stimulation-induced cytokine responses is influenced in part by age, gender, seasonality, and gut microbiome. Host genetic regulators especially single nucleotide polymorphisms in multiple immune gene loci, particularly the TLR1-TLR6-TLR10 locus, have been identified using individuals of predominantly European descent. However, transferability of such findings to other populations is challenging. We are beginning to incorporate diverse population cohorts and leverage multi-omics approaches at single cell level to bridge the current knowledge gap. We believe that such an approach presents the opportunities to comprehensively assess both genetic and environmental factors driving variation seen in immune response phenotype and a better understanding of the molecular and biological mechanisms involved.Many studies have been done on the various factors affecting resistance to insecticides. The relationship between Wolbachia bacteria and resistance to insecticides is one of the factors that has attracted a lot of attentions. Wolbachia are obligatory intracellular endosymbionts that naturally occur in a wide range of arthropods and nematodes, including the mosquito Culex quinquefasciatus. Initially, the presence of bacteria was proved by molecular assays. Then the resistance level of this species was evaluated in adults against DDT 4.0% and deltamethrin 0.05% using the standard WHO guideline. After elimination of Wolbachia by tetracycline and its proof by molecular assays, the susceptibility tests were conducted again on uninfected line. Finally, the two lines were compared in terms of responding to insecticides. The findings indicated that there is no significant correlation between susceptibility of two lines in response to DDT 4.0% while they represented a significant correlation for deltamethrin (P =0.00). We propose that Wolbachia bacteria increase the susceptibility to deltamethrin but they show neutral effect on DDT susceptibility in Cx. quinquefasciatus. However, more studies on other vectors and insecticides still need to be done.

This study is aimed to assess the incidence of advanced opportunistic infections (OIs) and its predictors among Human Immunodeficiency Virus (HIV) infected children at Debre Tabor referral Hospital and University of Gondar Compressive specialized Hospitals, Northwest Ethiopia, 2020.

A retrospective follow-up study was conducted from June 1, 2010, to May 30, 2020. A total of 349 children under the age of 15 who had received Anti-Retroviral Therapy (ART) were included in the study. Data were entered into Epi info version 7.2 and then exported to Stata 14.0 for analysis. Kaplan Meier curve and Log-rank test were used to determine the median survival time and the discrepancy of different categorical variables. The Cox regression model was used to identify the predictors of advanced opportunistic infections. Hydroxyfasudil supplier The Adjusted hazard ratio (AHR) at 95% confidence interval (CI) was used to declare statistical significance.

The incidence rate of advanced opportunistic infection was 5.53 per 100 (95% CI 4.7, 6.9) Person per year observation (PYO).