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Incorporation of personal experiences into teaching was effective at stimulating reflective thought and will hopefully result in better resonation of concepts in practice.

Traditional textbook-based teaching methods may not be optimal for all topics. The role of personalizing content through sharing and connection should be further explored as a strategy to promote cultural safety in pharmacy education.

Educators and institutions should promote reflective practice for curricula designed to facilitate cultural safety. Sharing oneself with students may not always be a favored strategy but there could be other strategies identified through further reflection and research.

Educators and institutions should promote reflective practice for curricula designed to facilitate cultural safety. Sharing oneself with students may not always be a favored strategy but there could be other strategies identified through further reflection and research.

Faculty development should be based on the tenets of adult education, emphasizing active learning, engagement, relevance, and opportunities for application. The traditional approach, however, has focused on providing content in an instructor-centered fashion, relying predominantly on passive learning with infrequent learner engagement, minimal learner preparation, and poor use of performance assessment to drive growth.

By modeling the principles of educational psychology and adult learning theory (including involving the learner in the design and outcomes of the learning experience, using active learning strategies, and facilitating relationship development between learners and facilitators), faculty development can be transformed into a growth focused Quality Learning Environment (QLE).

Here, we call for a redesign of faculty development around the principles of a QLE as an investment in faculty growth and a healthier and more innovative faculty culture. A novel, four-stage approach is offered to support this transformation.

Here, we call for a redesign of faculty development around the principles of a QLE as an investment in faculty growth and a healthier and more innovative faculty culture. A novel, four-stage approach is offered to support this transformation.

To evaluate whether endometrial molecular profiles distinguish subsets of patients according to clinical characteristics, and to infer dysregulated immune networks, by measuring cytokines, chemokines, and growth factors in endometrial biopsy specimens from a cohort of infertile women with a high incidence of endometriosis.

Prospective cohort study.

Department of Gynecology at a university hospital.

Patients undergoing laparoscopy for infertility assessment (n = 103).

Endometrial biopsies were performed during surgery. Fertility outcome and clinical parameters were registered preoperatively and after 6 months.

The concentrations of 48 factors in endometrial biopsy specimens were analyzed with respect to clinical status in univariate and multivariate frameworks.

The concentrations of 44 factors from endometrial tissues of 74 patients were suitable for analysis. Although the tissue concentrations of interleukin (IL)15, IL-7, and interferon γ-induced protein (IP)-10 were individually lower in patienc from nonendometriotic patients, implicating uterine natural killer cells in endometriosis.

Previous studies have demonstrated that non-White patients with colorectal liver metastasis (CRLM) were significantly less likely to undergo liver metastasectomy compared to White patients. The aim of this study is to evaluate differences in access to liver metastasectomy for CRLM according to race and hospital-year volume of liver surgery (HVLS).

The National Cancer Database (2011-2017) was used to identify patients with CRLM. Hospitals were stratified into quartiles according to HVLS. An adjusted Poisson regression model was used to evaluate the interaction between race and HVLS and access to liver metastasectomy.

We identified 27,340 patients with CRLM. Non-White patients were less likely to undergo a liver metastasectomy compared to White patients (RR 0.87, 95% CI 0.82-0.91, p<0.001). This racial disparity persisted at the highest quartile HVLS hospitals.

Receiving cancer care at hospitals with the highest HVLS did not translate into equal access to liver metastasectomy for non-White patients with CRLM.

Receiving cancer care at hospitals with the highest HVLS did not translate into equal access to liver metastasectomy for non-White patients with CRLM.

Ethanol ablation (EA) is a non-surgical option for the treatment of benign cystic thyroid nodules. This study summarizes our preliminary experience with the efficacy and safety of EA.

A retrospective analysis was performed of patients undergoing EA for symptomatic, benign, cystic and predominantly cystic (≥75%) thyroid nodules. Baseline nodule volume, cosmetic scores, and symptom scores were assessed, as well as volume reduction ratio (VRR), cosmetic and symptom scores at post-procedure months 1, 3, 6, and 12.

31 patients underwent an uncomplicated EA for a single cyst with an average volume of 21.3cc (range 1.7-101.4cc). Follow-up was limited by the COVID-19 pandemic. Mean nodule VRRs were 66±20% (1m, n=17), 87±15% (3m, n=9), 72±20% (6m, n=7), and 78% (12m, n=3). Mean symptom and cosmetic scores decreased concurrently post-procedure.

EA is a safe, effective option for benign cystic and predominantly cystic thyroid nodules.

EA is a safe, effective option for benign cystic and predominantly cystic thyroid nodules.Severe asthma is a heterogeneous disease encompassing different phenotypes and endotypes. Although patients with severe asthma constitute a small proportion of the total population with asthma, they largely account for the morbidity and mortality associated with asthma, indicating a clear unmet need. Being distinct from mild and moderate disease, new insights into the immunopathogenesis of severe asthma are needed. The disease endotypes have provided better insights into the immunopathogenic mechanisms underlying severe asthma. Current stratified approach of treating severe asthma based on phenotypes is met with shortcomings, necessitating unbiased multidimensional endotyping to cope with disease complexity. Therefore, in this review, we explore the distinct endotypes and their mechanistic pathways that characterize the heterogeneity observed in severe asthma.This article has been retracted please see Elsevier Policy on Article Withdrawal (https//www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Publications Committee of the ASRM. The authors have plagiarized part of a paper that had already appeared in Hum Reprod 1997;12487-90. https//doi.org/10.1093/humrep/12.3.487. One of the conditions of submission of a paper for publication is that authors declare explicitly that their work is original and has not appeared in a publication elsewhere. Re-use of any data should be appropriately cited. As such, this article represents a severe abuse of the scientific publishing system. The scientific community takes a very strong view on this matter, and apologies are offered to readers of the journal that this was not detected during the submission process.

To estimate the probability of clinical or multiple pregnancy during ovulation induction (OI)/ovarian stimulation (OS).

Secondary analysis of two multicenter randomized clinical trials (combined).

Multicenter.

A total of 750 women with polycystic ovary syndrome and 900 women with unexplained infertility.

Ovulation induction/OS with either timed intercourse (polycystic ovary syndrome) or intrauterine insemination.

Clinical and multiple pregnancy rates/cycle, cumulative pregnancy rates. Age, body mass index, parity, diagnosis, medication, markers of ovarian reserve, and ovarian response were considered in multivariable regression models for clinical, multiple, and cumulative pregnancy rates. Receiver operating characteristic curves were created for clinical and multiple pregnancy rates.

Younger patient and partner age, treatment type, lower body mass index, and medication dose were all associated with clinical pregnancy. Variables associated with multiple pregnancy included the abovementioned varicine.yale.edu/CalDirect.html).

Assessing Multiple Intrauterine Gestations after Ovulation Stimulation NCT01044862; PPCOSII NCT00719186.

Assessing Multiple Intrauterine Gestations after Ovulation Stimulation NCT01044862; PPCOSII NCT00719186.Intracytoplasmic sperm injection (ICSI) was introduced for male infertility but is now used in many other techniques in assisted reproduction. Indications for ICSI use need to be re-evaluated to ensure appropriate application in infertility management.Over the past 40 years, since the publication of the original WHO Laboratory Manual for the Examination and Processing of Human Semen, the laboratory methods used to evaluate semen markedly changed and benefited from improved precision and accuracy, as well as the development of new tests and improved, standardized methodologies. Herein, we present the impact of the changes put forth in the sixth edition together with our views of evolving technologies that may change the methods used for the routine semen analysis, up-and-coming areas for the development of new procedures, and diagnostic approaches that will help to extend the often-descriptive interpretations of several commonly performed semen tests that promise to provide etiologies for the abnormal semen parameters observed. As we look toward the publication of the seventh edition of the manual in approximately 10 years, we describe potential advances that could markedly impact the field of andrology in the future.

Gluten-free diet (GFD) is a lonely lifelong management for patients with celiac disease (CD), which may affect their quality of life (QoL). This can be evaluated by generic or specific instruments. We aimed to translate, validate and cross-culturally adapt a specific-CD instrument to Moroccan-Arabic version (M-CD-DUX), and then apply it to evaluate the QoL of Moroccan celiac children.

CD-DUX instrument was translated and culturally adapted, and preliminarily evaluated on 15 children and their proxies. The reproducibility and internal consistency of M-CD-DUX were measured by intra-class coefficient (ICC) and Cronbach α tests respectively. The statistical analysis of data consisted was conducted using SPSS, and the Goodness-of-Fit test was measured by SPSS AMOS.

The reliability of M-CD-DUX instrument showed a good internal consistency and reproducibility. The psychometric properties of M-CD-DUX were acceptable, and the instrument's Model fit was good [(Root Mean Square Error of Approximation = 0.062; χ2 = 603.08, p < 0.001]. M-CD-DUX was completed by 52 celiac children and their proxies. It showed a worse QoL for all items and subscales, and no difference was observed between the QoL of celiac children already under GFD and those recently diagnosed.

M-CD-DUX was the first reliable and adapted instrument used to evaluate the QoL of celiac children in an Arab country, emphasizing a negative impact of CD on their QoL.

Therefore, improving their QoL requires to make gluten-free products available to them at an appropriate price as well as a good integration into society.

Therefore, improving their QoL requires to make gluten-free products available to them at an appropriate price as well as a good integration into society.