Adkinsadair0239

The impact of serum uric acid (SUA) on atherosclerosis has been suspected to be epiphenomenal owing to its close relationship with metabolic abnormalities. The aim of the present study was to evaluate the association between SUA levels and arterial stiffness in the absence of established cardiovascular (CV) disorders.

The relationship between SUA levels and brachial-ankle pulse wave velocity (baPWV) was examined in 353 asymptomatic adults (57±8years, 11.9% men) without established CV disorders defined as systolic blood pressure (BP) ≥140mmHg or diastolic BP≥90mmHg; total cholesterol ≥240mg/dL; low-density lipoprotein cholesterol ≥160mg/dL; high-density lipoprotein cholesterol <40mg/dL; fasting glucose ≥126mg/dL; body mass index ≥25.0kg/m

 ; current smoking; and history of medication for hypertension, diabetes, and dyslipidemia. Subjects were stratified into four groups based on the quartiles of their SUA levels.

Mean baPWV was significantly different in all groups group I, 1320±195cm/s; group II, 1336±195cm/s; group III, 1404±199cm/s; and group IV, 1483±248cm/s (P<.001). SUA levels were significantly correlated with baPWV (r=.364) (P<.001). Multivariate linear regression analysis showed that SUA (β 32.93; 95% confidence interval [CI] 18.99-54.87), together with age (β 11.44; 95% CI 9.36-13.53) and systolic BP (β 8.98; 95% CI 6.80-11.16), was significantly associated with baPWV (P<.001).

High SUA levels have an independent association with increased arterial stiffness even in subjects without established CV disorders.

High SUA levels have an independent association with increased arterial stiffness even in subjects without established CV disorders.

Persistent hyperparathyroidism (pHPT) is frequently seen after transplantation contributing to post-transplant complications.

We conducted a retrospective single center analysis to explore the relationship of early pHPT and long-term allograft outcome. Patients were divided into high (N=153) and low (N=252) PTH groups based on serum parathyroid hormone (PTH) level 3months post-transplant (PTH≥150 and<150pg/mL, respectively).

High PTH was found to be an independent predictor for reduced kidney allograft function up to 3years post-transplant. eGFR decreased by 11.4mL/min (P<.001) and the odds of having an eGFR<60mL/min 3years post-transplant were sixfold higher (P<.01) in the high compared to the low PTH group. Subgroup analysis based on eGFR 1year post-transplant, presence of slow graft function (SGF), and transplant type revealed similar results. High PTH three months post-transplant was also independently associated with an increased risk for overall mortality and for death with a functioning graft (P<.05).

pHPT three months post-renal transplantation is an independent predictor for a worse allograft function up to 3years post-transplant and a risk factor for mortality. This relationship remains statistically significant after accounting for baseline allograft function, presence of SGF and serum mineral levels abnormalities.

pHPT three months post-renal transplantation is an independent predictor for a worse allograft function up to 3 years post-transplant and a risk factor for mortality. This relationship remains statistically significant after accounting for baseline allograft function, presence of SGF and serum mineral levels abnormalities.

HeartMate 3 is a left ventricular assist device, composed of a centrifugal pump. It can be applied as a myocardial recovery, a bridge to transplant, or a destination therapy, in the treatment of patients with left ventricular heart failure.

Herein we describe a technique applied against a giant aneurysmal dilatation, which combines a surgical device implantation and a left ventricular reconstruction using a double patch.

The patch minimizes thrombotic risk thanks to its internal bovine pericardium layer, which is in contact with blood.

The outlined technique is relatively reproducible and safe in a selected group of patients, as it employs a high-quality device and enables the restoration of an appropriate ventricular geometry.

The outlined technique is relatively reproducible and safe in a selected group of patients, as it employs a high-quality device and enables the restoration of an appropriate ventricular geometry.

This analysis identifies the correlates of 60- and 120-day telephone-based study follow-ups among community-dwelling adults in North Central Florida.

Six thousand three hundred and fortyparticipants were recruited by Community Health Workers from the University of Florida's community engagement program with a face-to-face baseline and two phone follow-ups assessing indicators of health.

Physical disability versusnone (adjusted odds ratio [aOR], 1.5; 95% confidence interval [CI], 1.2─1.9), high trust in research versusnone (aOR, 1.5; 95% CI, 1.1─2.1), history of research participation versusnone (aOR, 1.6; 95% CI, 1.3─2.0), having health insurance versusnone (aOR, 1.4; 95% CI,1.1─1.7), interest in research participation versusnone (aOR, 1.8; 95% CI, 1.3─2.7), and no drug use versusdrug use (aOR, 0.5; 95% CI, 0.3─0.9) significantly predicted completion of follow-up.

Health and social factors such as disability, insurance, history of and interest in research, trust and no drug use significantly predicted completing two follow-ups. These findings can facilitate efforts to minimize attrition in the research enterprise.

Health and social factors such as disability, insurance, history of and interest in research, trust and no drug use significantly predicted completing two follow-ups. These findings can facilitate efforts to minimize attrition in the research enterprise.Pityriasis rubra pilaris (PRP) is an erythematous-desquamative dermatitis that is sometimes associated with non-scarring alopecia. Despite the fact that the disease can be disfiguring, scarring alopecia has rarely been described in this disease. Here, we present a 69-year-old woman who developed an erythrodermic episode of PRP associated with telogen effluvium that left an area of persistent alopecia of the scalp and resulted in hair loss in the eyebrows. The biopsy of that area of the scalp demonstrated a scarring alopecia with lichen-planopilaris-like features. Despite this histopathology, the alopecia responded well to treatment. This finding expands the context in which lichen planopilaris features can be found and demonstrates their good prognosis under early treatment.

The San Francisco Valley region from Brazil is known worldwide for its fruit production and exportation, especially grapes and wines. The grapes have high quality not only due to the excellent morphological characteristics, but also to the pleasant taste of their fruits. Such features are obtained because of the climatic conditions present in the region. In addition to the favorable climate for grape cultivation, harvesting at the right time interferes with fruit properties.

This work aims to define grape maturation stage of Syrah and Cabernet Sauvignon cultivars with the aid of deep-learning models. The idea of working with these algorithms came from the fact that the techniques commonly used to find the ideal harvesting point are invasive, expensive, and take a long time to get their results. In this work, convolutional neural networks were used in an image classification system, in which grape images were acquired, preprocessed, and classified based on their maturation stage. Images were acquired with varying illuminants that were considered as parameters of the classification models, as well as the different post-harvesting weeks. The best models achieved maturation classification accuracy of 93.41% and 72.66% for Syrah and Cabernet Sauvignon respectively.

It was possible to correctly classify wine grapes using computational intelligent algorithms with high accuracy, regarding the harvesting time, corroborating chemometric results. © 2020 Society of Chemical Industry.

It was possible to correctly classify wine grapes using computational intelligent algorithms with high accuracy, regarding the harvesting time, corroborating chemometric results. © 2020 Society of Chemical Industry.

Stress echocardiography (SE) is an established technique for assessment of coronary artery disease (CAD) which is difficult to perform and interpret. Left ventricular stroke volume (SV) is readily estimated with Doppler echocardiography. It can be affected by myocardial ischemia, with possible adjunctive value during SE.

Patients underwent Bruce protocol SE with SV estimated before and after maximal treadmill exertion post routine regional wall analysis. Incremental change in SV (ΔSV) with exercise was measured.

A derivation cohort (n=273) was established to test the hypothesis. An optimal cutoff for detection on inducible ischemia was ΔSV ≤ +10mL. The validation cohort of consecutive patients (n=1093, 376 [34%] female; age 59±12years) were followed clinically after SE for 20460 patient-months. There were 1000 patients with nonischemic SE, and 93 patients with studies suggestive of myocardial ischemia. Secondary analysis yielded 831 patients with a normal exercise response (ΔSV>+10mL) and 192 with an abnormal ΔSV ≤ +10mL. Time to first combined adverse cardiac event (composite of angina, acute coronary syndrome, cardiac revascularization, worsening New York Heart Association (NYHA) class, a reduction in EF, and cardiovascular death) was analyzed and adjusted using Cox proportional hazards regression. The hazard ratio for an adverse event with an abnormal ΔSV response (≤10mL) was 10.3 (95% confidence intervals 5.6-19.1, P<.0001).

Stroke volume assessment during SE is feasible and readily performed. It is simple, practical, and has incremental diagnostic and prognostic value when added to exercise regional wall-motion analysis.

Stroke volume assessment during SE is feasible and readily performed. It is simple, practical, and has incremental diagnostic and prognostic value when added to exercise regional wall-motion analysis.

To determine whether suicidal ideation or suicide attempts are linked to poor neurocognitive function among individuals with first-episode schizophrenia (FES).

We performed a cross-sectional study on 159 Chinese inpatients (M

=27.1years; 52.2% females) with minimal-treated FES and collected their suicidal history through interviews and medical records. Neurocognitive performance, psychopathology, and depressive symptoms were assessed using the MATRICS Consensus Cognitive Battery, the Positive and Negative Syndrome Scale, and the Calgary Depression Scale for Schizophrenia, respectively.

Approximately 1/10 FES inpatients had any suicide attempts, and more than 1/4 reported lifetime suicidal ideation. Inpatients with a suicide attempt or suicidal ideation scored significantly worse in the overall seven neurocognitive domains compared with those without past suicidal ideation or a suicide attempt. Linear regression suggested that suicide attempts were mainly associated with lower scores in working memory and speed of processing, after adjusting for education levels. The associations remained robust after further controlling for psychopathological and depressive symptoms.

First-episode schizophrenia patients with suicide attempts had more severely impaired neurocognitive performances in specific domains. Fundamental neurocognitive dysfunctions should be assessed, detected, and treated after their suicide risk assessments.

First-episode schizophrenia patients with suicide attempts had more severely impaired neurocognitive performances in specific domains. Fundamental neurocognitive dysfunctions should be assessed, detected, and treated after their suicide risk assessments.