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Accumulation of microplastics (MPs) in marine organisms poses an imminent environmental threat and health risk due to the possibility of trophic transfer of accumulated MPs in ecologically important food chains. In this context, a field-level study was conducted on the fishing grounds of the north eastern part of the Arabian Sea through experimental fishing, and the gastrointestinal tracts (GT) of three different species of shrimps (n=180) were examined for the incidence of microplastics. The results showed that all shrimp caught from the fishing grounds had significant levels of MPs in the gastrointestinal tracts. A total number of 1220 microplastic items were recorded from the pooled samples, with an average of 6.78 ± 2.80 items per individual. The gastrointestinal tract showed an average number of 70.32 ± 34.67 MPs per gram of the gut material. The MPs with the size range of 100-250 μm were the most abundant form found in the shrimp species analyzed. Among the colored MP particles, black color was the most dominant (30.16%) form of MP. Fibers, fragments, pellets, beads, and films were the common morphotypes; however, fibers showed an occurrence of 39.40%, 47.39%, and 41.89% in the GTs of Metapenaeus monoceros, Parapeneopsis stylifera, and Penaeus indicus, respectively. In the present study, six types of plastic polymers were identified from the GTs of the studied samples. The findings confirm the presence of microplastics in the natural habitats of shrimps beyond the coast and indicate that shrimps caught from these coastal fishing grounds contain MPs in their gut. The findings underline the immediate scientific intervention for the microplastic reduction in the marine environment.Fine particulate matter (PM2.5) is one of the major air pollutants. A large number of epidemiological and experimental studies have shown that PM2.5 pollution can cause adverse health consequences, which has attracted more public attention. In order to have a deeper and more structured understanding of the research progress and frontiers on the impact of PM2.5 on health, in this study, we used the bibliometrics software CiteSpace to analyze the relevant literature in this field. The results show that since 2000, the relevant literature has increased steadily, especially in the last 5 years, and the number of publications in China has increased rapidly. The United States has the most publications. The Chinese Academy of Sciences and Professor Joel Schwartz are the most published institution and author, respectively, and many articles have been published in the journal of Environmental Health Perspectives. Over time, studies on the health effects of PM2.5 have gradually deepened. In addition to a more comprehensive study of its harmful effects, the related molecular mechanisms have also been further explored. We believe that countries and regions should strengthen cooperation and jointly solve the harm caused by PM2.5 through the integration of multiple disciplines and fields. In addition, the adverse health consequences and its related mechanisms caused by exposure to ultrafine particle, different chemical components of PM2.5, as well as the intervention of the health effects caused by PM2.5 need to be further studied.The novel COVID-19 is a highly invasive, pathogenic, and transmittable disease that has stressed the health care sector and hampered global development. Information of other viral respiratory diseases indicates that COVID-19 transmission could be affected by varying weather conditions; however, the impact of meteorological factors on the COVID-19 death counts remains unexplored. By investigating the impact of meteorological factors (absolute humidity, relative humidity, and temperature), this study will contribute both theoretically and practically to the concerned domain of pandemic management to be better prepared to control the spread of the disease. For this study, data is collected from 23 February to 31 March 2020 for Milan, Northern Italy, one of the badly hit regions by COVID-19. The generalized additive model (GAM) is applied, and a nonlinear relationship is examined with penalized spline methods. A sensitivity analysis is conducted for the verification of model results. The results reveal that temperature, relative humidity, and absolute humidity have a significant but negative relationship with the COVID-19 mortality rate. Therefore, it is possible to postulate that cool and dry environmental conditions promote virus transmission, leading to an increase in COVID-19 death counts. The results may facilitate health care policymakers in developing and implementing effective control measures in a timely and efficient way.Identifying sources of nitrate contamination has been a long-term challenge in areas with different land uses. We investigated the biogeochemical processes and quantified the contribution of potential nitrate sources in the Nanyang Basin, the source area of the South to North Water Diversion Project in China. Hydrogeochemical characteristics, the dual-isotope method (δ15N-NO3- and δ18O-NO3-), and the Bayesian mixing model (SIAR) were combined. The results for 160 samples indicated that mean nitrate concentrations of residential area (162.83 mg L-1) and farmland (75.71 mg L-1) were higher compared with those of surface water (16.15 mg L-1) and forest (36.25 mg L-1). Hydrochemical facies and molar ratios of major ions indicated that the natural environment was greatly impacted by anthropogenic activities. Nitrification, ammonium volatilization, and mixing effects were the dominant processes in nitrogen transformation. The contributions of different sources to nitrate contamination were 45.41%, 35.81%, 17.87%, and 0.91% for sewage and manure, soil organic nitrogen, synthetic fertilizer, and atmospheric deposition, respectively. Undeveloped infrastructure and sewage disposal in rural areas were the main causes of nitrate contamination. Our results provide a theoretical basis for the development of measures to guarantee long-term water supply of the South to North Water Diversion Project.Despite the importance of remittance inflows as potential source of incomes for recipient households and one of main contributors to the development process in various developing countries, their environmental effects have been largely neglected in empirical literature. To fill this gap, the current study proposes an extension of the conventional environmental Kuznets curve by performing a modified version based on remittance inflows in both low- and middle-income countries from 1980 to 2014. Using the novel method of moments quantile regression with fixed effect, the outcomes provide evidence of an inverted N-shaped Kuznets curve for remittances at higher carbon dioxide emitters in lower middle-income countries, proving that remittances allow recipient households to shift toward clean energy pattern (production/consumption). We find U-shaped curve for remittances from the 40th to 80th quantiles in upper middle-income countries along with monotonic negative effect on carbon dioxide emissions at highest quantiles (90th and 95th). No significant effect on environment has been outlined at lower carbon dioxide emitters for all panels. Regarding economic growth, an inverted N-shaped curve has been observed across all quantiles in upper middle-income countries and from lower to middle quantiles in low-income countries. Finally, financial development, as control variable, exerts significant mixed effect on carbon dioxide emissions, swung between positive at all quantiles in low- and upper middle-income countries and negative at lower quantiles in low-income countries. Some recommendations were further built in the present study.The water industry plays an important role in reducing greenhouse gas (GHG) emissions and therefore, moving to a low-carbon urban water cycle is of great importance. However, traditional performance assessment of water companies ignores GHG emissions. To overcome this limitation and to compare productivity change estimations of water companies excluding and including GHG emissions, this study computes the Luenberger productivity indicator (LPI) and the Malmquist-Luenberger productivity index (MLPI), respectively. Moreover, in a second stage, we investigate the impact of exogenous variables on environmentally sensitive productivity change estimations. The empirical application conducted for a sample of water and sewerage companies in England and Wales over the period 201-2019 has illustrated that when GHG emissions were considered in the assessment (i.e., MLPI estimations), average productivity decreased. By contrast, when productivity estimation ignored GHG emissions (i.e., LPI), average productivity increased. Hence, it is concluded that the inclusion of GHG emissions in productivity analysis impacted the results. This finding is very relevant from a policy perspective as it illustrates the importance of considering GHG emissions when evaluating the performance of water companies for regulatory purposes.

Tenofovir disoproxil fumarate (TDF) and Entecavir (ETV) are commonly used for patients with chronic hepatitis B (CHB), and renal or bone toxicity are possible concerns. This study is to evaluate the renal and bone effect of TDF compared with ETV in CHB patients.

This is a retrospective study at Kaohsiung Chung-Gung memorial hospital, Taiwan, from June 2013 to December 2018. Patients with CHB were prescribed with TDF or ETV for 3years or above. Renal function was assessed at 12-week intervals. Dual-energy X-ray absorptiometry scans of the spine and femurs were performed at 48-week intervals. The propensity score analysis was conducted to balance the baseline characteristics of patients in both treatment groups.

A total of 258 patients were included in this study TDF (n = 135) and ETV (n = 123). The prevalence of osteopenia was much higher in the TDF group at week 48 and week 96. The TDF group showed significant mean percentage decrease from baseline in bone mineral density throughout the treatment course. Logistic regression analysis adjusted for the propensity score demonstrated that the use of TDF was the only predictive factor of significant bone density loss at week 144. The mean percentage decline of estimated glomerular filtration rate was significant in the TDF group at all time points. Renal threshold phosphate concentration was similar among both treatment groups.

This study suggested CHB patients treated with TDF may experience increased risks of bone loss and renal deficits compared to those treated with ETV.

This study suggested CHB patients treated with TDF may experience increased risks of bone loss and renal deficits compared to those treated with ETV.

Calcifying odontogenic cysts (COC) and adenomatoid odontogenic tumors (AOT) have similar radiographic findings. We examined the radiographic and computed tomography (CT) images of patients histologically diagnosed with COC or AOT and identified their characteristic findings.

The subjects included 12 patients histologically diagnosed with COC or AOT (one female and five males per group), who underwent CT at our hospital between Nov 1998 and Jun 2019. The location of the lesion, impacted tooth, bone expansion, root resorption, tooth migration, calcified body, and presence or absence of a high-intensity zone in the marginal area of the lesion were examined.

In patients with COC, five patients with COC exhibited bone expansion toward the buccal side. The lesion encompassing the crown was attached to the cement-enamel junction and contained a radiopaque lesion with a calcified body. In 6 patients with COC, irregularly shaped calcified bodies were observed with small tooth-like structures. In patients with AOT, all six patients with AOT exhibited bone expansion toward the buccal and lingual sides.

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