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The BIOFIRE System and Your Immune System

The BIOFIRE System provides syndromic infectious disease testing, empowering healthcare professionals to choose the right test, the first time. Patients benefit from faster diagnosis and more targeted treatment. Clinicians benefit from better stewardship of antibiotics. Labs save money and increase efficiency.

The BioFire FilmArray Pneumonia plus panel (PN panel) tests native sputum, endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 pathogens with clinical relevance and antimicrobial resistance genes. The panel provides semiquantitative results within an hour.

Respiratory

The burning of biomass (wood plants, agro-forestry and other organic material) produces gaseous pollutants as well as fine particles of matter that negatively impact the respiratory system. Climate change may increase the negative impacts of forest fires on human health.

In the United States wildfire smoke is linked to hospitalizations due to respiratory diseases like asthma, COPD, and lung cancer. In addition, this type of air pollution is an underlying risk factor for cardiovascular diseases and a significant contributing factor to the burden of illness in the most vulnerable populations that include those with lower socioeconomic status (SES).

In the COVID-19 pandemic, a number of communities were exposed to unhealthy levels of air pollution resulting from wildfires. The public health response has been limited to a public education campaign on symptom management. This gap in knowledge is troubling considering the evidence of potential health risks resulting from the continual exposure to smoke and other sources of poor air quality.

Researchers are now evaluating how to best protect the public's health during any future events of this kind. NIH is a research institution that studies this critical public health issue through the BLUE CORAL and FIRE CORAL studies.

For the first time the study is a prospective cohort study that will assess long-term outcomes from exposure to smoke from wildfires and other sources. FIRE CORAL recruits adult participants who are hospitalized for COVID-19 index episodes and speak English or Spanish but aren't pregnant. The Fire Coral protocol includes a variety of assessments in person that objectively measure pulmonary function testing, lung imaging and functional assessment.

Smoke and other particles can cause or worsen respiratory conditions such as emphysema, COPD and pneumonia. Smoke exposure can cause adverse effects on health. To minimize or avoid these negative effects, avoid outdoor activities and use the EPA "N95" mask. The mask is designed to trap small particles.

Smoking cigarettes can cause irritation to the eyes, throat and nose. To minimize symptoms the lungs need to be flushed with plenty of fluids and taking medications that decrease inflammation, such as corticosteroids.

Bloodstream

Your bloodstream is at the forefront of fighting off germs that enter your body. Dendritic cells, which are special cells, are akin to your fire department's call center; they take antigens (molecules that trigger an immune response) from invaders and then release proteins that signal other white blood cells to come to fight them. Circulating white blood cell counts, differentials and band cells were increased during firefighters' firefighting shifts, as compared to levels after strenuous physical exertion with no firefighting.

Skin

As the wildfires in California spewed smoke and dust into the air this past fall and winter dermatologists were concerned how this might affect the skin of those exposed to it. Maria Wei is a graduate student at the University of California, Irvine. She examines how extreme wildfire pollution affects the skin. click the following webpage was published in Scientific Reports on April 22nd.

Wei's study shows that the temperature changes of the skin according to the length of time the body has been exposed. It can take as long as two hours for a person's skin to reach its flash point--the temperature at which it starts to burn and turns to ash. That's why it's important to stay away from a fire or campfire, and why you should wear protective clothing when you are outside during a forest fire or even on the heat of the day.

While it is important to be aware of the dangers of fire-related pollution, there's no way to stop forest fires from happening. Wei believes that as climate change causes forests to burn faster, the number of people who suffer from wildfires will rise. This means that more people will need to wear long sleeves, hats, and thick moisturizers.

It's also worth noting that the atopic dermatitis (itchy skin) which many suffer from can be exacerbated by air pollution from wildfires. The reason for this is due to smoke particles can block pores, which makes the atopic dermatitis condition worse.

Another issue is that atopic dermatitis is known to make people more sensitive to UV light, which can be aggravated by smoke from wildfires. This can cause people to be more likely to visit tanning salons, and may cause them to tan with less protection than they should.

While a fire and ice facial can help lessen the effects of atopic skin dermatitis, it's not recommended for anyone who has an open wound or a rash on their face. Patients with active acne should avoid it as well, and if you're pregnant or breastfeeding it's recommended to stay clear of this treatment completely. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' premiere membership MedSpa It's a highly effective and effective facial that bridges the gap between a light facial and a peel without requiring any downtime. It's designed to smooth skin, improve rosacea, decrease fine lines and acne scarring and stimulate cellular regeneration. It's a fantastic treatment that will give you radiant skin.

Infections





The human body is made up of a complex system of organs and tissues which work together to guard against infections. Infections are caused by microscopic microorganisms like viruses, bacteria, parasites and fungus that invade healthy cells and cause them to multiply out of control. When this happens your immune system can react by displaying symptoms of illness. The symptoms could range from a runny or stuffy nose to stomach ache however, they may also include a high fever or swollen glands. You may also experience an skin rash. The severity of your symptoms may be affected by the type of disease, its location, and even your temperature.

Infections can be spread through a variety of methods, but the most common are from person to person through droplets that linger in the air after coughing or sneezing. This is how bacterial infections like tuberculosis, strep, and meningococcal illnesses and viral infections, such as the common cold and influenza, are transmitted. Some infections caused by bacteria, such as skin infections and sexually transmitted infections (STIs) like gonorrhea and chlamydia are transmitted by direct contact with infected tissues or mucous membranes, or through indirect contact with contaminated surfaces. Some bacterial diseases are transmitted by insects like mosquitoes, ticks or fleas and can be spread by bites from these bugs you.

The parasites, viruses, and other microorganisms are tiny enough that they can enter your bloodstream to infect your cells. This can lead to serious diseases such as the common cold or AIDS. Fungi can cause skin conditions like athlete's feet and ringworm, while others infect the respiratory tract and nervous system.

The BioFire PN Panel employs our revolutionary FilmArray technology to detect a complete list of pathogens involved in upper respiratory infections in sputum and samples of bronchoalveolar fluid. The kit comes with a reagent kit that includes all the chemistry required to perform reverse transcription, nested multiplex PCR and detection in one machine. It's a simple-to-use tool to assist clinicians in identifying syndromic patterns and treat patients with various respiratory symptoms. This test has been given an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high complexity laboratories.