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Mesothelioma and Asbestos Exposure

People who use products containing asbestos are at risk of breathing in or eating asbestos fibers. These fibers can penetrate the tissue of the chest cavity and abdomen and are called the pleura or the peritoneum.

Exposure to asbestos increases the risk of developing malignant pleural mysothelioma or peritoneal cancer throughout your lifetime. Although the risk appears to decrease after 40 years of exposure, even minimal asbestos exposure is dangerous.

Age

The older the person is when exposed, the greater the risk of developing mesothelioma. Mesothelioma is a type of cancer that affects the mesothelium which is a thin layer of tissue around major organs in the body. The cancerous cells multiply in uncontrolled ways and develop into tumors. Mesothelioma is usually diagnosed in those who have been exposed to asbestos, either in their job or as a member of someone who was exposed to it.

Asbestos exposure can cause mesothelioma because it causes irritation to the mesothelium. The lining of the lungs (pleura) is the most affected by mesothelioma pleural, but it can also affect the lining of the abdomen and peritoneum, as well as the lining of the heart (pericardium).

Asbestos is a non-porous and durable mineral. It was utilized in insulation, construction and other industrial applications prior to the 1980s. During this time many millions of Americans were exposed to asbestos as a result of their jobs or by being close to an exposed loved one.

When asbestos is disturbed it releases fibers into air. They can be breathed in, and they are too tough for the body to break down or process. The fibers can cause irritation and cancer in the lungs if they become stuck.

Mesothelioma symptoms are typically not likely to manifest until a long time after asbestos exposure. The symptoms are similar with other cancers, and may be fatal if treated.





Mesothelioma is more common in men than women, and is most often diagnosed in those who are over 45. People who are at most risk of developing mesothelioma because asbestos exposure at work include ship builders, miners railroad workers, and others who handled or installed products that contain asbestos. The asbestos on the clothing of these individuals can put their family members at risk.

Smoking

The longer a person is exposed to asbestos, the greater their risk of developing mesothelioma. This is due to the long time of latency, which can take between 20 and 60 years from initial exposure to diagnosis. Mesothelioma can occur in different parts of the body, based on the type and amount of asbestos. The lining of the chest wall and lung cavity (the pleura) is affected by pleural mesothelioma. Peritoneal mesothelioma forms in the abdominal lining, called the peritoneum.

Those who have been exposed to asbestos the most often develop mesothelioma that is found in their chests or lungs. Most at risk are those working in the fields of shipbuilding, power production and construction. Mesothelioma can also be a risk for those who were exposed at home or in schools to asbestos. Children and spouses of asbestos-exposed employees can carry asbestos-containing particles from their workplace to their homes on their clothes, skin, and hair. This puts them at risk.

People with mesothelioma are typically white and older than 65. They are more likely to have a blue-collar occupation or military background. Asbestos was used extensively by the United States Navy and other branches in the military because of its ability to withstand flames. Many veterans were exposed to asbestos.

Mesothelioma may develop when DNA of an individual undergoes changes which cause cells to multiply unchecked. This leads to the formation of tumors, which then transform into mesothelioma. The disease can affect any part of the body, but typically, it is found in the chest or abdomen.

Smoking does cause mesothelioma but it can increase your risk by increasing the amount asbestos you inhale. Anyone who has been exposed asbestos should quit smoking.

The treatment plan of a patient with mesothelioma should also include a doctor who is knowledgeable about asbestos exposure and risk factors. A specialist in mesothelioma who is knowledgeable to assist them determine the best approach to treat this rare cancer. The doctor will be able determine if a patient is eligible for experimental treatments or immunotherapy.

Asbestos Exposure

Asbestos is a natural mineral that is utilized in many different products including insulation, roofing and flooring. Workers who handle, make or work on asbestos-containing products are at high risk for exposure. Vimeo to loose asbestos fibers can lead to breathing them into the lungs, where they can cause illness or cancer.

There is a long time of time between exposure to asbestos and the onset of symptoms which makes it difficult to diagnose many asbestos diseases. Mesothelioma, the most dangerous of asbestos-related illnesses is not an exception. The symptoms of mesothelioma may develop between 20 and 60 years after asbestos exposure.

The most frequent way that people are exposed to asbestos is through occupational exposure. All jobs that require asbestos handling or use, including those in manufacturing, construction automobile mechanics, construction, and electrical. However, workers can be exposed to asbestos by home activities, such as smoking cigarettes or renovating older homes that have asbestos.

Inhalation of asbestos is the most frequent mesothelioma causing agent. Inhaling asbestos fibers can lead to the lungs, where they irritate a lining called the pleura. This irritation can lead to thickened pleura patches (pleural plates) and fibrosis within the lungs. As the disease progresses it could cause to the accumulation of fluid within the chest cavity, and eventually lung cancer. Mesothelioma can also affect the tissue of other organs including the abdomen and heart.

People who are exposed to asbestos at work are at the greatest chance of developing mesothelioma. However, those with a family history of mesothelioma or other asbestos-related illnesses are also at risk. The risk of asbestos exposure is increased if a person has held more than one job over the course of their life. Smoking can increase the risk of mesothelioma, however, it can also worsen the condition for those who are already diagnosed. If you have a history of exposure to asbestos and are suffering from mesothelioma, quitting smoking can prolong your life and improve the outcome of your treatment. Tell your doctor if you have been exposed to asbestos or experience any new symptoms like abdominal pain or difficulty to breathe. They may prescribe medication or perform surgery to treat the condition.

Genetics

Many cancers have a genetic connection which means that genetic factors could increase their risk of developing a particular disease. Mesothelioma, however, does not have a gene component. Exposure to asbestos is the main factor.

Asbestos fibers can enter the body via inhalation or swallowed, and then clinging to the chest's lining (the pleura) and the abdomen (the peritoneum) or around the heart (the pericardium). These loose fibers can damage the cells that make up these tiny linings over time. This can result in mesothelioma.

However, mesothelioma does not affect all people who are exposed. Researchers believe other factors can influence whether a person develops mesothelioma following exposure to asbestos. This includes age, gender, family history of mesothelioma, and other diseases, as well as any additional risk factors, such as smoking.

Men are more likely than women to develop mesothelioma. This could be due to the fact that men were more likely than women to have been exposed directly to asbestos while at work. Additionally, it takes between 20 and 60 years for mesothelioma to be diagnosed following a person's initial exposure to asbestos.

A faulty gene is another risk factor for mesothelioma. In a study of two families with mesothelioma incidences that were high, scientists found that nearly all members of the family carried an abnormal gene on their short arm chromosome 3. This gene, known as BAP 1 regulates the flow of calcium inside cells. With a faulty gene this process is disrupted and calcium levels drop. This allows asbestos to mutate healthy cells into cancerous ones, causing mesothelioma.

Additionally the mutated gene within the immune system of a person can increase the likelihood of developing mesothelioma from exposure to asbestos. People who have this mutation have a lower percentage of white blood cells, which are the cells that fight off cancerous cells.

The type of asbestos to which a person was exposed and the work they performed can increase a person's mesothelioma-related risk. In addition, the polio vaccine given to children in the 1940s and 1950s may increase the risk of mesothelioma by exposing them to the cancer-causing SV40 virus.