Zobrazení zdroje stránky Sullivansmed9249

38; 95%CI, 4.02-38.15; P less then .001). Coronary perforation occurred in 4 patients (3.9%) requiring covered stent implantation (without subsequent cardiac tamponade) and 2 patients (1.9%) had a stroke (one of which was a transient ischemic attack). During a median follow-up of 31 months, 3 (2.9%) patients died from cardiovascular causes and 13 (12.6%) required repeat target vessel revascularization. CONCLUSIONS Aorto-ostial occlusions represent a challenging subset for PCI. However, an acceptable success rate with favorable outcomes during follow-up can be achieved by experienced operators. The presence of interventional collaterals allowing the use of the retrograde approach is key for achieving procedural success. BACKGROUND No study has investigated the capability of high-resolution computed tomography (HRCT) to detect a lateral bronchus abnormality, degree of air bronchogram, and distribution of affected lesions in the diagnosis of Mycoplasma pneumoniae pneumonia (MPP). METHODS We prospectively enrolled patients with serologically-confirmed MPP or culture-confirmed other bacterial pneumonia (OBP). The distribution of affected areas, abnormalities in lateral bronchial lesions, the degree of air bronchogram, and previously reported findings on HRCT were evaluated for MPP and OBP. Predictive HRCT findings for MPP were determined by logistic regression analysis. We provisionally designed our HRCT criteria (negative, probable, or highly suspected) for diagnosing MPP and investigated the diagnostic yield of the HRCT criteria. RESULTS Sixty-three MPP and 126 OBP patients were included in this study. Logistic regression analysis showed that the absence of peripheral predominance, bronchial wall thickening, lateral bronchial wall thickening, intralobular or lobular ground-glass opacities, intralobular ground-glass opacities connected to a lateral bronchus, and less air bronchogram in infiltrates were significant predictors of MPP. Our HRCT criteria showed that the sensitivity and specificity in negative, probable, and highly suspected MPP were 0.0 and 0.33, 1.0 and 0.69, and 0.5 and 0.98, respectively. CONCLUSIONS HRCT had considerable ability to detect a lateral bronchial abnormality and to diagnose or rule out MPP based on the distribution of affected areas, abnormalities in lateral bronchial lesions, and the degree of air bronchogram in the infiltrates. V.BACKGROUND Existing research suggests patients with blood group O are less likely to develop pancreatic ductal adenocarcinoma (PDAC) compared to those with non-O blood groups, and that survival from PDAC may be affected by ABO blood type. This study assessed survival outcomes in PDAC patients who underwent pancreatoduodenectomy (PD) in one health system. METHODS From 2010 to 2017, demographic, operative, chemotherapy and survival data for patients undergoing PD at Emory Healthcare were reviewed. Patients with blood type AB were excluded due to small sample size. The relationship between ABO blood group and survival was analyzed using Kaplan-Meier survival curves and multivariate cox proportional regression analysis. RESULTS Of 449 PDAC patients assessed, 204 (45.4%), 60 (13.4%) and 185 (41.2%) were blood groups A, B and O, respectively. Patients were well matched in clinicopathologic characteristics. Median survival did not differ by blood group (p&nbsp;=&nbsp;0.82), and this relationship remained insignificant on cox regression analysis (p&nbsp;=&nbsp;0.15). On multivariate analysis, lymph node positivity (p&nbsp; less then &nbsp;0.001) and increasing age (p&nbsp;=&nbsp;0.001) were associated with reduced survival. CONCLUSION In contrast to recent reports, this larger study found that blood group did not impact overall survival among patients undergoing PD for PDAC. OBJECTIVES Limited literature supports the value of routine contact lens examinations. The purpose of this study is to document complications diagnosed when subjectively successful planned replacement soft contact lens patients are evaluated to renew their existing contact lens prescriptions. METHODS Asymptomatic soft contact lens patients who presented to the University Eye Center at Ketchum Health (Anaheim, CA) and the Eye and Vision Center at the Massachusetts College of Pharmacy and Health Sciences (Worcester, MA) for routine contact lens comprehensive exams to renew existing contact lens prescriptions were professionally evaluated and their complications documented. All subjects presented without complaint and had a history of subjectively successful planned replacement soft lens wear for at least 1 year. RESULTS A total of 202 subjects were recruited from both sites (age range 16-72 years; 76 male, 126 female; spherical contact lens optical power equivalent range +7.75D to -19.25D). Considering health issues, one hundred and five (52%) patients were found to exhibit at least one undiagnosed complication (95% CI 0.45-0.59) 70% were diagnosed with contact lens driven ocular complications; 54% were diagnosed with non-contact lens driven ocular health issues; and 4% showed signs of undiagnosed systemic disease. Of note, complication prevalence increases to 72% overall if both contact lens fit issues and contact lens care compliance problems are included as complications in analysis. CONCLUSIONS A striking ocular health and contact lens complication rate in asymptomatic soft contact lens wearers is demonstrated across two different study sites. This data suggests that asymptomatic as well as symptomatic contact lens wearers require routine professional evaluations. PURPOSE During image acquisition, certain topographers require the addition of sodium fluorescein (NaFl) dye to the tear film. This study investigates the effect of NaFl dye on corneal topography and tear surface quality. METHOD The E300 corneal topographer (Medmont International Pty Ltd., Victoria, Australia) was used to measure ocular surface topography and quality of 57 eyes of 57 healthy individuals without dry eye symptoms, age 35.1 ± 15.2 years (mean ± standard deviation) ranging between 19 and 65 years. The mean of three simulated keratometry values, a variety of corneal shape descriptors, and Tear Film Surface Quality (TFSQ) were measured under three different conditions; without NaFl (baseline), with the addition of a single dose NaFl, and using a double dose of NaFl. RESULTS Compared to baseline, the Inferior-Superior (IS) index decreased significantly after a single dose (P = 0.034) or double dose of NaFl (P = 0.030). [https://www.selleckchem.com/products/l-selenomethionine.html L-SelenoMethionine] The corneal surface was significantly more regular without NaFl (P = 0.003) or one insertion of NaFl (P = 0.