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A difference larger than +/- 5 percent points was defined as a biased result, precluding laboratory-based surveillance for guiding empirical treatment. We observed high prevalence of AMR ranging between 63.1% (piperacillin-tazobactam) and 85% (ceftriaxone) in laboratory-based surveillance and 41.3% (piperacillin-tazobactam) and 74.2% (ceftriaxone) in population-based surveillance, except for amikacin and meropenem (5.7%/9.8%; 10.8%/5.9%; [laboratory-/population-based surveillance], respectively). Laboratory-based surveillance yielded significantly higher AMR prevalence estimates than population-based surveillance. This difference was much larger when comparing surveillance data from outpatients than from inpatients. All point estimates of the difference between the two surveillance systems were larger than 5 percent points, except for amikacin and meropenem. Laboratory-based AMR surveillance of uropathogens, is not adequate to guide empirical treatment for community-based settings in Indonesia.Nitrogen (N) fertilization affects bioenergy crop growth and productivity and consequently carbon (C) and N contents in soil, it however remains unclear whether N fertilization and crop type individually or interactively influence soil organic carbon (SOC) and total N (TN). In a three-year long fertilization experiment in switchgrass (SG Panicum virgatum L.) and gamagrass (GG Tripsacum dactyloides L.) croplands in Middle Tennessee USA, soil samples (0-15cm) were collected in plots with no N input (NN), low N input (LN 84 kg N ha-1 yr-1 in urea) and high N input (HN 168 kg N ha-1 yr-1 in urea). Besides SOC and TN, the aboveground plant biomass was also quantified. In addition to a summary of published root morphology data based on a separated mesocosm experiment, the root leachable dissolved organic matter (DOM) of both crops was also measured using archived samples. Results showed no significant interaction of N fertilization and crop type on SOC, TN or plant aboveground biomass (ABG). Relative to NN, HN (not LN) significantly increased SOC and TN in both crops. Though SG showed a 15-68% significantly higher ABG than GG, GG showed a 9.3-12% significantly higher SOC and TN than SG. The positive linear relationships of SOC or TN with ABG were identified for SG. However, GG showed structurally more complex and less readily decomposed root DOM, a larger root volume, total root length and surface area than SG. Collectively, these suggested that intensive N fertilization could increase C and N stocks in bioenergy cropland soils but these effects may be more likely mediated by the aboveground biomass in SG and root chemistry and morphology in GG. Future studies are expected to examine the root characteristics in different bioenergy croplands under the field fertilization experiment.While movement patterns of grazing ungulates are strongly dependent on forage quality their use of nutrient hotspots such as termite mounds or grazing lawns has rarely been quantified, especially in savanna ecosystems where soil-nutrient quality is low. Additionally, few experiments have been conducted to determine the role of termite mound- and grazing lawn-derived soils in improving forage quality in the field. We studied wild ungulate grazing activities around ten termite mounds, six grazing lawns and their respective control sites in a Miombo system of Issa Valley, western Tanzania, in the same system. We used indirect observations (i.e., dung, tracks) to identify seasonal and spatial variations in habitat use of various wild mammalian grazers. Grazer visitation rates were nine and three times higher on termite mounds and grazing lawns, respectively, compared to control sites. During the rainy season, termite mounds were more frequently used than grazing lawns while the latter were used more often during the dry season. In an additional pot experiment with soils derived from different areas, we found that Cynodon dactylon in termite mound-derived soils had twice as high Nitrogen and Phosphorous contents and biomass compared to grasses planted in grazing lawn soils and control site soils. We highlight that both termite mounds and grazing lawns play a significant role in influencing seasonal nutrient dynamics, forage nutrient quality, habitat selectivity, and, hence, grazing activities and movement patterns of wild ungulate grazers in savannas. We conclude that termite mounds and grazing lawns are important for habitat heterogeneity in otherwise nutrient-poor savanna systems.BACKGROUND Air pollution has been associated with cognitive function and brain volume. While most previous research has examined the association between air pollution and brain volume in cortical structures or total brain volume, less research has investigated associations between exposure to air pollution and subcortical structures, including the thalamus. Further, the few available previous studies investigating associations between air pollution and thalamic volume have shown mixed results. METHODS In this study, we evaluated the association between PM2.5, PM2.5-10, PM10, nitrogen dioxide, and nitrogen oxides and volume of the thalamus in adults using the UK Biobank resource, a large community-based sample, while adjusting for multiple covariates that could confound an association between air pollution and thalamic volume. RESULTS In adjusted models, the left but not right thalamus volume was significantly inversely associated with PM2.5-10, although there were no significant associations between PM2.5, PM10, nitrogen dioxide, and nitrogen oxides with either left or right thalamic volumes. [https://www.selleckchem.com/products/Azacitidine(Vidaza).html 5-Azacytidine order] In addition, interactions between age and PM2.5-10 and PM10 were inversely associated with thalamic volume, such that thalamic volume in older people appeared more vulnerable to the adverse effects of PM2.5-10 and PM10, and interactions between educational attainment and PM2.5, nitrogen dioxide, and nitrogen oxides and between self-rated health and PM2.5-10 were positively associated with thalamic volume, such that higher educational attainment and better self-rated health appeared protective against the adverse effects of air pollution on the thalamus. CONCLUSION These findings suggest a possible association between thalamic volume and air pollution particularly in older people and in people with comparatively low educational attainment at levels of air pollution found in the United Kingdom.