Zobrazení zdroje stránky Riismortensen4064

Caregiver substance abuse is associated with harmful parenting behaviors, increased child welfare involvement, and negative child outcomes, and the opioid epidemic has brought increased attention to the safety and wellbeing of children living with caregivers who abuse substances.<br /><br /> This paper investigates the impact of primary caregiver drug abuse concerns on child welfare investigations in Ontario, Canada and examines how different drug abuse categories impact out-of-home placements in a Canadian setting, with a focus on opioids, opiates, and morphine derivatives.<br /><br /> Secondary analyses of data from the Ontario Incidence Study of Reported Child Abuse and Neglect 2018 (OIS-2018) were conducted. The OIS-2018 collected information on child welfare investigations from workers who conducted the investigations. The final unweighted sample of the OIS-2018 included 7590 investigations involving children under 18years old.<br /><br /> Descriptive and bivariate analyses were conducted as well as a logistic regression predicting out-of-home placement.<br /><br /> Investigations involving noted primary caregiver drug abuse concerns involved increased household and family risks as well as more intrusive forms of child welfare involvement. Results of the logistic regression controlling for family, child, and case characteristics revealed that investigations involving noted primary caregiver drug abuse were more likely to involve out-of-home placements, and investigations that involved caregivers who abused opioids specifically were approximately 3.5 times more likely to result in a placement.<br /><br /> A coordinated response involving the child welfare, addictions treatment, and other allied systems is warranted to support families with substance abuse concerns and provide appropriate services.<br /><br />A coordinated response involving the child welfare, addictions treatment, and other allied systems is warranted to support families with substance abuse concerns and provide appropriate services.Arsenic (As) exposure is a global public health concern affecting millions worldwide and stems from drinking water and foods containing As. Here, we assessed how agronomic practices and postharvest fermentation techniques influence As concentrations in rice bran, and calculated health risks from consumption. A global suite of 53 rice brans were tested for total As and speciation. Targeted quantification of inorganic As (iAs) concentrations in rice bran were used to calculate Target Hazard Quotient (THQ) and Lifetime Cancer Risk (LCR) across the lifespan. Mean iAs was highest in Thailand rice bran samples (0.619 mg kg-1) and lowest in Guatemala (0.017 mg kg-1) rice bran samples. When comparing monosodium-methanearsonate (MSMA) treated and the Native-soil counterpart under the irrigation technique Alternate Wetting and Drying (AWD) management, the MSMA treatment had significantly higher total As (p = 0.022), and iAs (p = 0.016). No significant differences in As concentrations were found between conventional and organic production, nor between fermented and non-fermented rice bran. Health risk assessment calculations for the highest iAs-rice bran dosage scenario for adults, children and infants exceeded THQ and LCR thresholds, and LCR was above threshold for median iAs-rice bran. This environmental exposure investigation into rice bran provides novel information with food safety guidance for an emerging global ingredient.In order to solve the low sorption capacity of pristine biochar for anionic pollutants, e.g., reactive red 120 (RR120), a novel mesoporous Fe-biochar composite was fabricated in this study by combination of Fe-loading and ball-milling methods. The ball-milling Fe-biochar composite could effectively remove RR120 by up to 90.1 mg g-1 at pH of 7.5, and slightly alkaline condition was preferred. Adsorption kinetics showed that ball-milling Fe-biochar composite could quickly sorb RR120 with the rate constant (k2) of 2.07 g mg-1 min-1 (pH = 7.5). [https://www.selleckchem.com/products/--mk-801-maleate.html Dizocilpine] Positive surface charge and large surface area were responsible for the outstanding removal performance of RR120 by ball-milling Fe-biochar composite (1) The adscititious Fe would be converted to β-FeOOH during pyrolysis, which significantly improved the zeta potential of biochar and thus facilitated the electrostatic adsorption for RR120, which contributed to 42.3% and 85.5% at pH of 3 and 7.5, respectively; (2) Ball-milling effectively increased the specific surface area and uniformed the pore size distribution, which could provide more sorption sites and expedite the diffusion of RR120 molecules, shortening the time from several hours to less than 15 min. Findings of this study not only provide a feasible modification method for biochar to adsorb anionic pollutants efficiently and rapidly, but also help to reveal the roles of Fe-loading and ball-milling in enhancing adsorption capacity.<br /><br /> Ankle mobility is known to be of uttermost importance to generate propulsive forces and control balance during gait initiation. Impaired mobility of the postural chain occurs with normal ageing and is exacerbated in patients with Parkinson's disease. This study questions whether short-term stretching session applied to the triceps surae improves ankle mobility and, consequently, dynamical postural control in patients with Parkinson's disease performing gait initiation.<br /><br /> Nineteen patients with Parkinson's disease participated in this study and were randomly assigned to an "intervention group" or a "sham group". In the intervention group, patients were exposed to a 4×60 seconds triceps surae stretching. In the sham group, they were exposed to forearm stretching. Additionally, ten age-matched healthy elderly, who were not exposed to any stretching-treatment, were assigned to a "control group". Participants performed series of gait initiation on a force-plate before and after their treatment.<br /><br /> Ankle mobility dynamical postural control depends on postural chain mobility.<br /><br /> During the ongoing pandemic of COVID-19, wearing face masks was recommended, including patients with epilepsy doing the hyperventilation (HV) test during electroencephalogram (EEG) examination somewhere. However, evidence was still limited about the effect of HV with face mask on cortical excitability of patients with epilepsy. The motivation of this work is to make use of the graph theory of EEG to characterize the cortical excitability of patients with epilepsy when they did HV under the condition wearing a surgical face mask.<br /><br /> We recruited 19 patients with epilepsy and 17 normal controls. All of participants completed two HV experiments, including HV with face mask (HV+) and HV without a mask (HV). The interval was 30 min and the sequence was random. Each experiment consisted of three segments resting EEG, EEG of HV, and EEG of post-HV. EEG were recorded successively during each experiment. Participants were asked to evaluate the discomfort degree using a questionnaire when every HV is completed.<br /><br /> All + . We should pay more attention to the adverse effect on brain network excitability caused by HV + in patients with epilepsy. In the clinical practice under the COVID-19 pandemic, it is important that the wearing face mask remain cautious for the individuals with epilepsy when they carried out HV behavior such as exercise (e.g., running, etc.).Organophosphorus pesticides (OPs) are posing great threat to the environment and human health, due to their overuse and persistence in the environment. Photolysis has been established as an effective method to degrade OPs. The influence of pH value, the initial concentration of pesticides and the light source on the photolysis of two OPs, including chlorpyrifos and dimethoate, was investigated. The optimal reaction condition for OPs degradation was under pH 9, with xenon lamp as the light source, in which the photodegradation efficiencies of chlorpyrifos and dimethoate (500 mg/L) were 75.12% and 94.31%, respectively. The photodegradation products of chlorpyrifos and dimethoate were identified by GC-MS. Also, density functional theory (DFT) calculations were used to characterize the molecular properties of chlorpyrifos and dimethoate, as well as predicting potential photolysis reactions. Photodegradation mechanisms of chlorpyrifos and dimethoate were proposed, in which 3,5,6-trichloropyridinol (TCP), O,O-diethyl thiophosphate (DETP), 2,3,5-Trichloro-6-methoxypyridine (TMP) and O,O,S-trimethyl phosphorothioate were identified as the main products of chlorpyrifos degradation. Omethoate, O,O,S-trimethyl thiophosphorothioate, N-methyl-2-sulfanylacetamide, O,O,O-trimethyl thiophosphate, O,O,S-trimethylphosphorothiate, and O,O,O-trimethyl phosphoric ester as the main photodegradation products for dimethoate. The main degradation mechanisms included ring opening, cleavage, oxidation and demethylation. This work demonstrated the feasibility of combining chemical analysis with quantum chemical calculation in unraveling degradation mechanisms of OPs. Also, it is of great significance for evaluating the environmental fate of OPs in aquatic system and further environmental risk assessment.New observations and updated models now suggest terrestrial ecosystems are net sink of atmospheric mercury (Hg), and the critical constrained process to identify the strengths of terrestrial sink is whether the large amount of Hg stored in vegetation originates from the soil as well as from the atmosphere. In this study, field open top chambers (OTCs) experiments reveal that rice plant can assimilate gaseous elemental mercury (GEM, Hg0) from the atmosphere through stomata, and Hg concentrations in rice leaves, upper and bottom stalks and grains increased with Hg0 levels in air, showing significantly quadratic linear relationships. Coupling field stable isotope soil amendment experiments, atmospheric source of Hg in rice plant is quantified with more than 90% of Hg accumulation in rice aboveground biomass from air and approximately 80% of rice root Hg from soil. Furthermore, elevated atmospheric carbon dioxide (CO2) exposure led to lower Hg concentration in rice tissues through reduction stomatal conductance of rice leaf, and subsequently impact the capacity of Hg storage in rice aboveground parts from the atmosphere. The findings from experiments provide a foundation for future quantification of atmospheric sink of crops in local and larger scales and comprehensive evaluation atmosphere - terrestrial processes and exposure risks in the global Hg cycling.Groundwater is the main source of drinking water for a significant portion of the human population. In many agricultural areas, diffuse pollution such as high levels of total dissolved salts including nitrate, puts the quality of this resource at risk. However, the effect of exposure to these water contaminants on brain development is currently poorly understood. Here we characterised water from a borewell located in an intensely cultivated area (agricultural) or water from a borewell located in a nearby pristine forest. The agricultural borewell water was rich in nitrates with high total dissolved salts. We then studied the consequence of drinking the agricultural water on mouse brain development. For this, the agricultural borewell water or forest water was given to mice for 6 weeks before and during pregnancy and lactation. The brains of the offspring born to these dams were analysed at postnatal day (P)5 and P21 and compared using immunohistochemistry for changes in glial cells, neurons, myelin, and cell death across many brain regions.