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Background Limited data is available for reliable and accurate predictors of in-hospital mortality in patients diagnosed with COVID-19. Methods This scientific study is a retrospective cohort study of patients without a known history of liver diseases who were hospitalized with COVID-19 viral infection. Patients were stratified into low score groups (Model of End-Stage Liver Disease [MELD] score less then 10) and high score groups (MELD ≥10). Clinical outcomes were evaluated, including in-hospital mortality, hospital length of stay, and intensive care unit length of stay (ICU LOS). Results Our cohort of 186 COVID-19 positive patients included 88 (47%) women with a mean age of 60 years in the low score group and mean age of 73 years in the high score group. Patients in the high score group were older in age (p less then 0.0001) and more likely to have history of diabetes mellitus (p=0.0020), stage 3 chronic kidney disease (CKD) (p=0.0013), hypertension (p less then 0.0001), stroke/transient ischemic attack (TIA) (p=0.0163), asthma (p=0.0356), dementia (p less then 0.0001), and chronic heart failure (p=0.0055). The in-hospital mortality or discharge to hospice rate was significantly higher in the high-score group as opposed to the low-score group (p=0.0014). Conversely, there was no significant difference among both groups in the hospital length of stay (LOS) and ICU LOS (p=0.6929 and p=0.7689, respectively). Conclusion Patients hospitalized with COVID-19 infection and found to have a MELD score greater than or equal to 10 were found to have a higher mortality as compared to their counterparts. Conversely a low MELD score is a very strong indicator of a more favorable prognosis, indicating hospital survival. We propose using the MELD score as an adjunct for risk stratifying patients diagnosed with COVID-19 without prior history of liver dysfunction.Introduction While immediate complications of ED patients undergoing endotracheal intubation (ETI) have been explored, the relationship between ED ETI and patient status at hospital discharge is unknown. Methods We performed a retrospective review of all intubations performed in our ED for one calendar year in adult patients (&gt;18 years of age). We abstracted patient and ETI factors (indication, complications, etc.) to determine their impact on patient outcomes. We defined a poor outcome as either (1) death or discharge to a nursing home if admitted to the hospital from home or (2) death if admitted to the hospital from a nursing home. We examined the univariate odds ratios for poor outcomes. Results We identified 122 intubations; 64 (52.5%) had a poor outcome and 58 (47.5%) did not have a poor outcome. Age in years (odds ratio [OR] 1.04, 95% confidence interval [CI] 1.02-1.07) and ETI performed for an indication of "cardiac arrest" (OR 4.49, 95% CI 1.55-13.01) were the only variables associated with a poor outcome. Other patients and intubation variables were not associated with a poor outcome including; gender, difficult airway characteristics, intubator skill level, first attempt success, airway complications, and post-intubation hypoxia or hypotension. Conclusion In our sample from a single ED, over 50% of patients who undergo ED ETI either died in the hospital or failed to return home. [https://www.selleckchem.com/products/fx11.html selleck chemical] While age and an ETI indication of "cardiac arrest" were associated with poor outcomes, future work is required to validate our findings in a larger cohort.Chronic back pain is a common complaint in the United States. In patients from endemic areas, spinal tuberculosis should be a part of the differential diagnosis, especially after the failure of conventional pain management treatments. Although most cases of tuberculosis present with pulmonary complaints, presented here is a case of isolated spinal tuberculosis with contiguous spread to the kidneys with the formation of psoas abscesses.Verrucous sarcoidosis is a rare cutaneous variant of sarcoidosis, an inflammatory disease characterized by non-caseating granulomas that primarily involves the lungs. The current literature on verrucous sarcoidosis is limited, with the majority of lesions presenting on the lower extremities of African American males. Here, we present two cases that highlight the unique manifestations of this uncommon cutaneous entity. The first case involves a middle-aged Hispanic woman with lesions on her arms and face, and the second case involves a middle-aged African American woman with sole facial involvement. A multi-disciplinary approach to diagnosis and treatment is required as verrucous sarcoidosis can present with clinical and histopathological features indistinguishable from infectious etiologies and has an association with pulmonary sarcoidosis. Adalimumab has demonstrated success in the treatment of verrucous sarcoidosis.Seronegative myasthenia gravis is a rare, but potential adverse effect of immune checkpoint inhibition. There have been few but increasing number of cases reported in recent years, and early recognition is important for prompt diagnosis and management. Here, we describe the case of a 65-year-old male with metastatic renal cell carcinoma on pembrolizumab diagnosed with new-onset seronegative myasthenia gravis and review literature on its management.Renal cell carcinoma (RCC) is a rare malignancy that often metastasizes to the lung, bones, liver, and brain. Only a few cases of RCC metastasis in periocular areas have been reported in the literature. This case report describes a 70-year-old male who was presented to the University of Florida, Gainesville ophthalmology clinic with two-day symptoms of diplopia, decreased vision, and mechanical ptosis of the left eye with superior temporal mass. The patient had a history of both prostate and RCC that were in remission for five years leading to his presentation. Excisional biopsy confirmed the metastasis of RCC to the eye. The patient reported no systemic symptoms. This report also reviews existing literature on RCC metastasis to the eye and orbit. Ultimately, RCC metastasis to the eye in patients with a history of known RCC should be considered in the differential diagnosis in those presenting with an atypical mass in periocular regions.