Zobrazení zdroje stránky Normanschulz9045

To evaluate antinociceptive efficacy and safety of SC buprenorphine hydrochloride administration in African pygmy hedgehogs (<br /><br /> ).<br /><br /> 12 healthy adult hedgehogs (7 males and 5 females).<br /><br /> 3 crossover experimental trials were performed. In the first trial, all 12 hedgehogs were given single SC injections of buprenorphine (0.01 mg/kg [0.0045 mg/lb]), buprenorphine (0.03 mg/kg [0.014 mg/lb]), or saline (0.9% NaCl) solution (0.16 mL/kg [0.073 mL/lb]), and sedation and hind limb thermal withdrawal latency were measured. In the second trial, 6 hedgehogs were given single SC injections of buprenorphine (0.05 mg/kg [0.023 mg/lb]) or saline solution (0.16 mL/kg), and sedation and withdrawal latency were evaluated. In the third trial, 10 hedgehogs were given 3 doses of buprenorphine (0.05 mg/kg, SC, q 24 h) or saline solution (0.16 mL/kg, SC, q 24 h), and food intake and body weight were measured for 6 days.<br /><br /> For all 3 experimental trials, the sedation score was 0 for all hedgehogs at all assessment times. A single 0.01-mg/kg dose of buprenorphine significantly increased thermal withdrawal latency for 36 hours, and single 0.03- and 0.05-mg/kg doses significantly increased latencies for 48 hours. Increased locomotor activity was noted in a few hedgehogs after administration of the 0.03- and 0.05-mg/kg doses. Daily administration of buprenorphine did not have significant effects on food intake or body weight.<br /><br /> SC administration of buprenorphine at single doses of 0.01, 0.03, and 0.05 mg/kg provided safe, long-lasting antinociception in African pygmy hedgehogs without apparent sedative effects.<br /><br />SC administration of buprenorphine at single doses of 0.01, 0.03, and 0.05 mg/kg provided safe, long-lasting antinociception in African pygmy hedgehogs without apparent sedative effects.<br /><br /> A 6-month-old male Miniature Dachshund was referred for examination and correction of a unilateral pes varus deformity.<br /><br /> Clinical examination and diagnostic imaging revealed varus, procurvatum, and internal torsion of the distal aspect of the left tibia causing intermittent lameness.<br /><br /> True spherical osteotomy performed with a dome-shaped saw allowed correction of the deformity in 3-D, and orthogonal internal plate fixation provided stabilization. No intraoperative or immediate postoperative complications developed. Outcome as judged by the clinician and the owners was satisfactory 2 weeks after surgery and excellent at each subsequent assessment. The patient remained free of clinical signs at the last follow-up 30 months after surgery.<br /><br /> To the authors' knowledge, this case represented the first time a true spherical osteotomy was used to correct a pes varus deformity in a canine patient.<br /><br />To the authors' knowledge, this case represented the first time a true spherical osteotomy was used to correct a pes varus deformity in a canine patient.<br /><br /> A 15-year-old 0.412-kg (0.906-lb) sexually intact male eclectus parrot (<br /><br /> ) was evaluated because its owners found it lethargic and dyspneic at the bottom of its cage.<br /><br /> The parrot was thin and had generalized muscle wasting, diffuse feather loss, pale mucous membranes, and melena. The coelomic cavity was distended and soft on palpation, with coelomic effusion suspected. Results of a CBC indicated leukocytosis with left shift heterophilia, including toxic heterophils, lymphopenia, and anemia. Plasma biochemical analyses revealed severe hyperamylasemia.<br /><br /> Radiography revealed no evidence of a metallic foreign body but severe loss of coelomic detail, suggestive of a coelomic mass, coelomic effusion with coelomitis, or both. Ultrasonography and CT revealed severe accumulation of coelomic fluid; a large, heterogeneous, irregularly marginated, and moderately vascularized mass in the caudal aspect of the coelomic cavity; and multiple hepatic, coelomic, and pulmonary nodules. On the basis of a poor prognosis, the parrot was euthanized. Necropsy results confirmed exocrine pancreatic adenocarcinoma, with disseminated metastases in the liver, gastrointestinal tract, coelomic cavity, and lungs.<br /><br /> In birds, pancreatic adenocarcinoma is rarely reported but should be considered a differential diagnosis for hyperamylasemia, coelomic mass, coelomic effusion, or abnormal gastrointestinal signs, alone or in combination. Ultrasonography and CT can be useful in further evaluating such patients and should be considered in the diagnostic plan.<br /><br />In birds, pancreatic adenocarcinoma is rarely reported but should be considered a differential diagnosis for hyperamylasemia, coelomic mass, coelomic effusion, or abnormal gastrointestinal signs, alone or in combination. Ultrasonography and CT can be useful in further evaluating such patients and should be considered in the diagnostic plan.<br /><br /> To examine the association between prerace administration of phenylbutazone and the risk of musculoskeletal injury (MSI) and fatal injury in Thoroughbred racehorses that raced between 2006 and 2015 at 2 of the 4 official racetracks in Argentina.<br /><br /> Data from racetrack databases and veterinary reports on 283,193 race starts.<br /><br /> Data were collected relating to race performance and injury outcomes for starts at these tracks. The incidence of MSI and fatal injury was calculated for each year, stratified by the declared prerace administration of phenylbutazone. Univariable logistic regression, followed by multivariable logistic regression, was used to identify significant risk factors for both MSI and fatal injury.<br /><br /> Analyses identified associations between the declared prerace administration of phenylbutazone and the risk of MSI and fatal injury during racing. Horses with declared prerace phenylbutazone administration had greater odds of MSI (OR, 1.45 [95% CI, 1.03 to 2.04]) and fatal injury (OR, 1.59 [95% CI, 1.fare in North and Latin America.<br /><br /> A 2-year-old spayed female domestic shorthair cat was evaluated for recurring estrous behavior after ovariohysterectomy and 2 subsequent exploratory laparotomies.<br /><br /> Physical examination revealed no abnormalities. A serum sample tested positive for anti-Müllerian hormone and had a progesterone concentration consistent with the presence of an ovarian remnant. Results of abdominal ultrasonographic examination suggested presence of a slightly hyperechoic mass caudal to the left kidney.<br /><br /> Exploratory laparotomy was performed when the cat was showing estrous behavior. Tissues at the right and left ovarian pedicles and the uterine stump appeared grossly normal but were excised and submitted for histologic examination. Two small nodules associated with the omentum were removed, and histologic examination results for one of these nodules indicated ovarian tissue with secondary and graafian follicles. [https://www.selleckchem.com/products/tariquidar.html Tariquidar] Clinical signs of estrus resolved after surgery, and hormonal assay results were within ranges expected for an ovariectomized cat.